Reds vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 14

Odds updated as of 6:11 a.m.

The Cincinnati Reds versus the Chicago White Sox is on the MLB schedule for Wednesday.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Reds vs White Sox Game Info

• Cincinnati Reds (20-23) vs. Chicago White Sox (13-29)
• Date: Wednesday, May 14, 2025
• Time: 7:14 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: FDSOH and CHSN

Reds vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-225) | CHW: (+188)
• Spread: CIN: -1.5 (-110) | CHW: +1.5 (-110)
• Total: 9 -- Over: (-105) | Under: (-115)

Reds vs White Sox Probable Starting Pitchers

Probable Pitchers: Nick Lodolo (Reds) - 3-3, 3.23 ERA vs Davis Martin (White Sox) - 1-4, 4.01 ERA

The Reds will give the ball to Nick Lodolo (3-3, 3.23 ERA), who is eyeing win No. 4 on the season, and the White Sox will turn to Davis Martin (1-4, 4.01 ERA). Lodolo's team is 5-3-0 against the spread in his starts this season. When Lodolo starts a game and his team is the favorite on the moneyline, they have a record of 2-2. When Martin starts, the White Sox have gone 2-5-0 against the spread. The White Sox have a 1-6 record in Martin's seven starts this season when they were the moneyline underdog.

Reds vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (68.7%)

Reds vs White Sox Moneyline

• Looking at the moneyline for Reds-White Sox, Cincinnati is the favorite at -225, and Chicago is +188 playing on the road.

Reds vs White Sox Spread

• The Reds are favored by 1.5 runs at home versus the White Sox. The Reds are -110 to cover the spread, while the White Sox are -110.

Reds vs White Sox Over/Under

• The over/under for the Reds versus White Sox game on May 14 has been set at 9, with -105 odds on the over and -115 odds on the under.

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Reds vs White Sox Betting Trends

• The Reds have been chosen as favorites in 16 games this year and have walked away with the win nine times (56.2%) in those games.
• These are the best odds of a victory sportsbooks have given Cincinnati this season, with a -225 moneyline set for this game.
• The Reds and their opponents have gone over in 18 of their 41 games with a total set by sportsbooks this season.
• The Reds are 21-20-0 against the spread in their 41 games with a line set by sportsbooks this season.
• The White Sox have won 12 of the 40 games they were listed as the moneyline underdog this season (30%).
• Chicago has gone 2-13 when playing as a moneyline underdog with odds of +188 or longer (13.3%).
• The White Sox have played in 41 games with an over/under set, and have combined with opponents to go over the total 19 times (19-20-2).
• The White Sox have a 22-19-0 record against the spread this season (covering 53.7% of the time).

Reds Player Leaders

• Elly De La Cruz has 42 hits, which ranks first among Cincinnati hitters this season, while batting .250 with 12 extra-base hits. He has an on-base percentage of .324 and a slugging percentage of .405.
• Among qualifying batters in baseball, his batting average ranks 89th, his on-base percentage ranks 91st, and he is 88th in slugging.
• TJ Friedl has an OPS of .741, fueled by an OBP of .359 and a team-best slugging percentage of .382 this season. He's batting .274.
• Among all qualifying players, he is 48th in batting average, 44th in on-base percentage and 107th in slugging percentage.
• Gavin Lux leads Cincinnati with an OBP of .370 this season while batting .276 with 20 walks and 15 runs scored.
• Jose Trevino is batting .307 with a .340 OBP and 10 RBI for Cincinnati this season.

White Sox Player Leaders

• Miguel Vargas has racked up 31 hits with a .314 on-base percentage, leading the White Sox in both categories. He's batting .221 and slugging .350.
• Including all qualifying players in MLB, he ranks 128th in batting average, 102nd in on-base percentage and 128th in slugging percentage.
• Luis Robert is batting .179 with three doubles, five home runs and 20 walks. He's slugging .313 with an on-base percentage of .284.
• His batting average is 156th among all qualified players, his on-base percentage is 130th, and he is 147th in slugging.
• Andrew Vaughn is batting .192 with seven doubles, five home runs and seven walks.
• Matthew Thaiss is batting .224 with four doubles, a home run and 19 walks.

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