Reds vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 14

Odds updated as of 7:11 p.m.

MLB action on Wednesday includes the Cincinnati Reds facing the Chicago White Sox.

We've got you covered, in terms of the most important information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Reds vs White Sox Game Info

• Cincinnati Reds (20-23) vs. Chicago White Sox (13-29)
• Date: Wednesday, May 14, 2025
• Time: 7:14 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: FDSOH and CHSN

Reds vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-196) | CHW: (+164)
• Spread: CIN: -1.5 (+105) | CHW: +1.5 (-126)
• Total: 8.5 -- Over: (-120) | Under: (-102)

Reds vs White Sox Probable Starting Pitchers

Probable Pitchers: Nick Lodolo (Reds) - 3-3, 3.23 ERA vs Davis Martin (White Sox) - 1-4, 4.01 ERA

The Reds will give the nod to Nick Lodolo (3-3) against the White Sox and Davis Martin (1-4). Lodolo and his team are 5-3-0 ATS this season when he starts. Lodolo's team has won 50% of his starts when they are favored on the moneyline (2-2). The White Sox have a 2-5-0 record against the spread in Martin's starts. The White Sox are 1-6 in Martin's seven starts this season that they were the moneyline underdog.

Reds vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (68.1%)

Reds vs White Sox Moneyline

• The Reds vs White Sox moneyline has Cincinnati as a -196 favorite, while Chicago is a +164 underdog on the road.

Reds vs White Sox Spread

• The White Sox are +1.5 on the run line against the Reds. The White Sox are -126 to cover, and the Reds are +105.

Reds vs White Sox Over/Under

• The over/under for the Reds versus White Sox contest on May 14 has been set at 8.5, with -120 odds on the over and -102 odds on the under.

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Reds vs White Sox Betting Trends

• The Reds have come away with nine wins in the 16 contests they have been listed as the favorites in this season.
• Cincinnati has been listed as a favorite of -196 or more on two occasions this season and split those games.
• The Reds and their opponents have hit the over in 18 of their 41 games with a total set by oddsmakers this season.
• The Reds have an against the spread mark of 21-20-0 in 41 games with a line this season.
• The White Sox are 12-28 in games they were the underdog on the moneyline (winning 30% of those games).
• Chicago has gone 4-16 when playing as a moneyline underdog with odds of +164 or longer (20%).
• In the 41 games bookmakers have set an over/under for the White Sox, they have combined with opponents to go over the total 19 times (19-20-2).
• The White Sox have covered 53.7% of their games this season, going 22-19-0 against the spread.

Reds Player Leaders

• Elly De La Cruz leads Cincinnati in total hits (42) this season while batting .250 with 12 extra-base hits. He has an on-base percentage of .324 and a slugging percentage of .405.
• Among all qualifying hitters in MLB, his batting average ranks 91st, his on-base percentage ranks 89th, and he is 86th in slugging.
• TJ Friedl has an OPS of .741, fueled by an OBP of .359 and a team-best slugging percentage of .382 this season. He's batting .274.
• His batting average is 49th among qualified players, his on-base percentage 46th, and his slugging percentage 105th.
• Gavin Lux has 37 hits this season and a team-best OBP of .370.
• Jose Trevino is batting .307 with a .340 OBP and 10 RBI for Cincinnati this season.

White Sox Player Leaders

• Miguel Vargas has accumulated 31 hits with a .314 on-base percentage, leading the White Sox in both statistics. He's batting .221 and slugging .350.
• Including all the qualified hitters in MLB, he is 128th in batting average, 100th in on-base percentage and 128th in slugging percentage.
• Luis Robert is hitting .179 with three doubles, five home runs and 20 walks. He's slugging .313 with an on-base percentage of .284.
• Including all qualified players, he is 156th in batting average, 130th in on-base percentage and 147th in slugging percentage.
• Andrew Vaughn has seven doubles, five home runs and seven walks while batting .192.
• Matthew Thaiss has four doubles, a home run and 19 walks while hitting .224.

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