Reds vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for May 4

Odds updated as of 1:11 a.m.
The Cincinnati Reds versus the Washington Nationals is on the MLB schedule for Sunday.
Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.
Reds vs Nationals Game Info
- Cincinnati Reds (18-16) vs. Washington Nationals (15-19)
- Date: Sunday, May 4, 2025
- Time: 4:10 p.m. ET
- Venue: Great American Ball Park -- Cincinnati, Ohio
- Coverage: FDSOH and MASN2
Reds vs Nationals Odds & Moneyline
- All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: CIN: (-116) | WSH: (-102)
- Spread: CIN: +1.5 (-194) | WSH: -1.5 (+160)
- Total: 8.5 -- Over: (-106) | Under: (-114)
Reds vs Nationals Probable Starting Pitchers
Probable Pitchers: Nicholas Martínez (Reds) - 1-3, 4.68 ERA vs MacKenzie Gore (Nationals) - 2-3, 3.51 ERA
The Reds will give the nod to Nicholas Martinez (1-3) against the Nationals and MacKenzie Gore (2-3). Martinez and his team are 2-4-0 ATS this season when he starts. Martinez's team is 1-1 this season when he starts and they're favored on the moneyline. The Nationals have gone 3-4-0 against the spread when Gore starts. The Nationals are 1-2 in Gore's three starts this season that they were the moneyline underdog.
Reds vs Nationals Prediction & Pick
All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (58.6%)
Reds vs Nationals Moneyline
- Looking at the moneyline for Reds-Nationals, Cincinnati is the favorite at -116, and Washington is -102 playing on the road.
Reds vs Nationals Spread
- The Nationals are 1.5-run favorites against the spread for this matchup with the Reds. The Nationals are +160 to cover, while the Reds are -194 to cover as a 1.5-run underdog on the runline.
Reds vs Nationals Over/Under
- The over/under for the Reds versus Nationals game on May 4 has been set at 8.5, with -106 odds on the over and -114 odds on the under.
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Reds vs Nationals Betting Trends
- The Reds have won in nine, or 56.2%, of the 16 contests they have been named as odds-on favorites in this year.
- This season Cincinnati has come away with a win eight times in 15 chances when named as a favorite of at least -116 on the moneyline.
- The Reds' games have gone over the total in 16 of their 33 opportunities.
- In 33 games with a line this season, the Reds have a mark of 18-15-0 against the spread.
- The Nationals have won 50% of the games this season they were the underdog on the moneyline (13-13).
- Washington is 12-12 (winning 50% of its games) when playing as a moneyline underdog of -102 or longer.
- The Nationals have combined with opponents to go over the total 17 times this season for a 17-15-0 record against the over/under.
- The Nationals have an 18-14-0 record ATS this season (covering 56.2% of the time).
Reds Player Leaders
- Elly De La Cruz has an OPS of .783, fueled by an OBP of .356 and a team-best slugging percentage of .427 this season. He has a .275 batting average.
- Among all qualified hitters in MLB, his batting average ranks 44th, his on-base percentage ranks 46th, and he is 68th in slugging.
- TJ Friedl has hit one homers this season while driving in 13 runs. He's batting .271 this season and slugging .353 with an on-base percentage of .327.
- Among all qualifying hitters, he is 54th in batting average, 73rd in on-base percentage and 119th in slugging percentage.
- Friedl brings a three-game streak with at least one hit into this matchup. In his last five games he is hitting .190 with a walk and an RBI.
- Gavin Lux leads Cincinnati with 33 hits and an OBP of .402 this season.
- Noelvi Marte is batting .297 with a .348 OBP and 17 RBI for Cincinnati this season.
Nationals Player Leaders
- James Wood has put up an on-base percentage of .384, a slugging percentage of .547, and has 35 hits, all club-bests for the Nationals (while batting .273).
- He ranks 50th in batting average, 21st in on-base percentage and 16th in slugging percentage among all qualified hitters in MLB.
- Wood enters this matchup on a three-game hitting streak. In his last five games he is hitting .368 with two doubles, five walks and an RBI.
- Nathaniel Lowe has six doubles, six home runs and 14 walks while batting .252. He's slugging .441 with an on-base percentage of .326.
- Including all qualifying hitters, he is 76th in batting average, 74th in on-base percentage and 59th in slugging percentage.
- Luis Garcia has five doubles, two home runs and eight walks while hitting .231.
- Keibert Ruiz is hitting .291 with four doubles, two home runs and seven walks.
Reds vs Nationals Head to Head
- 5/3/2025: 11-6 WSH (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -196, Underdog Moneyline: +164)
- 7/21/2024: 5-2 WSH (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
- 7/20/2024: 5-4 WSH (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
- 7/19/2024: 8-5 WSH (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
- 3/31/2024: 6-5 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
- 3/30/2024: 7-6 WSH (Favorite: Reds, Spread: -1.5, Total: 10.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
- 3/28/2024: 8-2 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
- 8/6/2023: 6-3 WSH (Favorite: Reds, Spread: -1.5, Total: 10.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
- 8/5/2023: 7-3 WSH (Favorite: Reds, Spread: -1.5, Total: 10.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
- 8/4/2023: 6-3 WSH (Favorite: Reds, Spread: -1.5, Total: 10.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
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