Reds vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for May 4

Odds updated as of 3:11 p.m.

The MLB's Sunday slate includes the Cincinnati Reds taking on the Washington Nationals.

All the info you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Reds vs Nationals Game Info

• Cincinnati Reds (18-16) vs. Washington Nationals (15-19)
• Date: Sunday, May 4, 2025
• Time: 4:10 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: FDSOH and MASN2

Reds vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-112) | WSH: (-104)
• Spread: CIN: +1.5 (-188) | WSH: -1.5 (+155)
• Total: 8.5 -- Over: (-112) | Under: (-108)

Reds vs Nationals Probable Starting Pitchers

Probable Pitchers: Nicholas Martínez (Reds) - 1-3, 4.68 ERA vs MacKenzie Gore (Nationals) - 2-3, 3.51 ERA

The Reds will give the nod to Nicholas Martinez (1-3, 4.68 ERA), who is eyeing win No. 2 on the season, and the Nationals will turn to MacKenzie Gore (2-3, 3.51 ERA). Martínez's team is 2-4-0 against the spread this season in his starts. Martinez's team is 1-1 this season when he starts and they're favored on the moneyline. When Gore starts, the Nationals are 3-4-0 against the spread. The Nationals are 1-2 in Gore's three starts this season that they were the moneyline underdog.

Reds vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (58.1%)

Reds vs Nationals Moneyline

• Looking at the moneyline for Nationals-Reds, Washington is the underdog at -104, and Cincinnati is -112 playing at home.

Reds vs Nationals Spread

• The Nationals are 1.5-run favorites against the spread for this matchup with the Reds. The Nationals are +155 to cover, while the Reds are -188 to cover as a 1.5-run underdog on the runline.

Reds vs Nationals Over/Under

• A combined run total of 8.5 has been set for Reds-Nationals on May 4, with the over at -112 and the under at -108.

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Reds vs Nationals Betting Trends

• The Reds have been chosen as favorites in 16 games this year and have walked away with the win nine times (56.2%) in those games.
• This season Cincinnati has come away with a win eight times in 15 chances when named as a favorite of at least -112 on the moneyline.
• The Reds and their opponents have gone over in 16 of their 33 games with a total set by sportsbooks this season.
• The Reds are 18-15-0 against the spread in their 33 games with a line set by sportsbooks this season.
• The Nationals have won 50% of the games this season they were the underdog on the moneyline (13-13).
• Washington is 12-12 (winning 50% of its games) when it has played as a moneyline underdog of -104 or longer.
• In the 32 games oddsmakers have set an over/under for the Nationals, they have combined with opponents to go over the total 17 times (17-15-0).
• The Nationals are 18-14-0 against the spread this season.

Reds Player Leaders

• Elly De La Cruz has an OPS of .783, fueled by an OBP of .356 and a team-best slugging percentage of .427 this season. He has a .275 batting average.
• Among qualified hitters in MLB, he is 44th in batting average, 46th in on-base percentage, and 69th in slugging.
• TJ Friedl has hit one homers this season while driving in 13 runs. He's batting .271 this season and slugging .353 with an on-base percentage of .327.
• Among qualified hitters, he ranks 54th in batting average, 75th in on-base percentage and 120th in slugging percentage.
• Friedl has picked up a hit in three games in a row. During his last five outings he is hitting .190 with a walk and an RBI.
• Gavin Lux leads his team in OBP (.402) and total hits (33) this season.
• Noelvi Marte is batting .297 with a .348 OBP and 17 RBI for Cincinnati this season.

Nationals Player Leaders

• James Wood has totaled 35 hits with a .384 on-base percentage and a .547 slugging percentage, all club-bests for the Nationals. He's batting .273.
• Including all qualified hitters in MLB, he is 50th in batting average, 23rd in on-base percentage and 17th in slugging percentage.
• Wood takes a three-game hitting streak into this game. During his last five outings he is batting .368 with two doubles, five walks and an RBI.
• Nathaniel Lowe is hitting .252 with six doubles, six home runs and 14 walks. He's slugging .441 with an on-base percentage of .326.
• His batting average ranks 77th among all qualified players, his on-base percentage ranks 76th, and he is 61st in slugging.
• Luis Garcia has five doubles, two home runs and eight walks while hitting .231.
• Keibert Ruiz is batting .291 with four doubles, two home runs and seven walks.

Reds vs Nationals Head to Head

• 5/3/2025: 11-6 WSH (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 7/21/2024: 5-2 WSH (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/20/2024: 5-4 WSH (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/19/2024: 8-5 WSH (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 3/31/2024: 6-5 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 3/30/2024: 7-6 WSH (Favorite: Reds, Spread: -1.5, Total: 10.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 3/28/2024: 8-2 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/6/2023: 6-3 WSH (Favorite: Reds, Spread: -1.5, Total: 10.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/5/2023: 7-3 WSH (Favorite: Reds, Spread: -1.5, Total: 10.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 8/4/2023: 6-3 WSH (Favorite: Reds, Spread: -1.5, Total: 10.5, Favorite Moneyline: -184, Underdog Moneyline: +154)

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