Reds vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for May 8

Odds updated as of 6:12 p.m.

The Friday schedule in MLB includes a matchup between the Cincinnati Reds and the Houston Astros.

All the info you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Reds vs Astros Game Info

• Cincinnati Reds (20-18) vs. Houston Astros (15-23)
• Date: Friday, May 8, 2026
• Time: 6:10 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: Reds.TV and SCHN

Reds vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-126) | HOU: (+108)
• Spread: CIN: -1.5 (+162) | HOU: +1.5 (-196)
• Total: 9 -- Over: (-108) | Under: (-112)

Reds vs Astros Probable Starting Pitchers

Probable Pitchers: Nick Lodolo (Reds) - 0-0, 0.00 ERA vs Mike Burrows (Astros) - 1-4, 5.97 ERA

The Reds will give the ball to Nick Lodolo and the Astros will turn to Mike Burrows (1-4, 5.97 ERA). In games Lodolo pitched with a spread last season, his team was 15-12-0 ATS. Lodolo and his team won 61.5% of the games he started as the moneyline favorite last season, with a record of 8-5. The Astros have a 1-6-0 ATS record in Burrows' seven starts that had a set spread. The Astros have a 1-3 record in Burrows' four starts this season when they were the underdog on the moneyline.

Reds vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (54.7%)

Reds vs Astros Moneyline

• Houston is a +108 underdog on the moneyline, while Cincinnati is a -126 favorite at home.

Reds vs Astros Spread

• The Astros are +1.5 on the spread (-196 to cover), and Cincinnati is +162 to cover the runline.

Reds vs Astros Over/Under

• Reds versus Astros, on May 8, has an over/under of 9, with the over being -108 and the under -112.

Bet on Cincinnati Reds vs. Houston Astros on FanDuel today!

Reds vs Astros Betting Trends

• The Reds have been favorites in 10 games this season and have come away with the win six times (60%) in those contests.
• Cincinnati has a record of 4-3 in contests when sportsbooks favor them by -126 or more on the moneyline.
• The Reds and their opponents have gone over in 22 of their 36 games with a total set by sportsbooks this season.
• The Reds have an against the spread mark of 22-14-0 in 36 games with a line this season.
• The Astros have won 42.9% of the games this season they were the moneyline underdog (9-12).
• When it has played as a moneyline underdog with odds of +108 or longer, Houston has an 8-11 record (winning 42.1% of its games).
• The Astros have had an over/under set by bookmakers 38 times, and have combined with opponents to go over the total in 25 of those games (25-12-1).
• The Astros have covered just 39.5% of their games this season, going 15-23-0 ATS.

Reds Player Leaders

• Sal Stewart is hitting .245 with six doubles, 10 home runs and 20 walks. He has an on-base percentage of .333 while slugging .497.
• Among all qualified hitters, he is 93rd in batting average, his on-base percentage ranks 90th, and he is 34th in slugging.
• Elly De La Cruz leads Cincinnati with 40 hits and an OBP of .337, plus a team-best slugging percentage of .510. He's batting .265.
• His batting average ranks 60th among qualified players, his on-base percentage 85th, and his slugging percentage 28th.
• Spencer Steer has collected 31 base hits, an OBP of .333 and a slugging percentage of .451 this season.
• Steer has recorded a hit in 10 games in a row. In his last 10 outings he is batting .353 with a double, two home runs, five walks and six RBIs.
• Nathaniel Lowe has six home runs, 16 RBI and a batting average of .270 this season.

Astros Player Leaders

• Yordan Alvarez has put up an on-base percentage of .423, a slugging percentage of .638, and has 45 hits, all club-bests for the Astros (while batting .319).
• Including all qualifying hitters, he ranks 11th in batting average, while his on-base percentage ranks fifth and he is sixth in slugging.
• Christian Walker has nine doubles, nine home runs and 15 walks while hitting .307. He's slugging .569 with an on-base percentage of .381.
• Including all qualifying hitters, he ranks 21st in batting average, 26th in on-base percentage and 11th in slugging percentage.
• Jose Altuve has nine doubles, three home runs and 17 walks while hitting .241.
• Isaac Paredes is batting .265 with six doubles, three home runs and 13 walks.

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