Red Sox vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 27

Odds updated as of 2:11 a.m.

Wednesday's slate in the MLB includes a matchup between the Boston Red Sox and the Baltimore Orioles.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Red Sox vs Orioles Game Info

• Boston Red Sox (73-60) vs. Baltimore Orioles (60-72)
• Date: Wednesday, August 27, 2025
• Time: 6:35 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and NESN

Red Sox vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-158) | BAL: (+134)
• Spread: BOS: -1.5 (-105) | BAL: +1.5 (-114)
• Total: 9 -- Over: (-118) | Under: (-104)

Red Sox vs Orioles Probable Starting Pitchers

Probable Pitchers: Brayan Bello (Red Sox) - 10-6, 3.07 ERA vs Dietrich Enns (Orioles) - 1-2, 4.97 ERA

The Red Sox will look to Brayan Bello (10-6) versus the Orioles and Dietrich Enns (1-2). Bello's team is 14-8-0 against the spread this season in his starts. Bello's team is 9-3 this season when he starts and they are the moneyline favorite. Enns has started two games with set spreads, and the Orioles went 1-1-0. The Orioles have not been a moneyline underdog when Enns starts this season.

Red Sox vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (57.2%)

Red Sox vs Orioles Moneyline

• Baltimore is the underdog, +134 on the moneyline, while Boston is a -158 favorite despite being on the road.

Red Sox vs Orioles Spread

• The Red Sox are at the Orioles and are favored by 1.5 runs on the spread. The Red Sox are -105 to cover the runline, with the Orioles being -114.

Red Sox vs Orioles Over/Under

• A combined run total of 9 has been set for Red Sox-Orioles on Aug. 27, with the over at -118 and the under at -104.

Bet on Boston Red Sox vs. Baltimore Orioles on FanDuel today!

Red Sox vs Orioles Betting Trends

• The Red Sox have won in 47, or 58.8%, of the 80 contests they have been named as odds-on favorites in this year.
• Boston has a record of 15-10 in contests when sportsbooks favor them by -158 or more on the moneyline.
• The Red Sox and their opponents have gone over in 64 of their 132 games with a total set by sportsbooks this season.
• The Red Sox have posted a record of 73-59-0 against the spread this season.
• The Orioles have a 32-38 record in games they were the underdog on the moneyline (winning 45.7% of those games).
• In games it has played as a moneyline underdog with odds of +134 or longer, Baltimore has a 5-11 record (winning just 31.2% of its games).
• In the 129 games bookmakers have set an over/under for the Orioles, they have combined with opponents to go over the total 56 times (56-69-4).
• The Orioles have gone 60-69-0 against the spread this season.

Red Sox Player Leaders

• Jarren Duran leads Boston with 132 hits and an OBP of .333, plus a team-best slugging percentage of .444. He's batting .256.
• Among qualifying hitters in the majors, his batting average ranks 87th, his on-base percentage ranks 71st, and he is 70th in slugging.
• Trevor Story is batting .260 with 22 doubles, 21 home runs and 28 walks, while slugging .431 with an on-base percentage of .306.
• Among qualified hitters, his batting average places him 74th, his on-base percentage 122nd, and his slugging percentage 80th.
• Ceddanne Rafaela is batting .247 with a .418 slugging percentage and 53 RBI this year.
• Alex Bregman has been key for Boston with 98 hits, an OBP of .385 plus a slugging percentage of .521.

Orioles Player Leaders

• Gunnar Henderson has accumulated an on-base percentage of .352, a slugging percentage of .468, and has 132 hits, all club-highs for the Orioles (while batting .281).
• Including all qualified hitters, he ranks 30th in batting average, while his on-base percentage ranks 39th and he is 47th in slugging.
• Jackson Holliday has 17 doubles, two triples, 15 home runs and 38 walks while batting .242. He's slugging .378 with an on-base percentage of .305.
• Including all qualifying hitters, his batting average puts him 116th, his on-base percentage ranks 124th, and he is 135th in slugging.
• Colton Cowser is hitting .226 with 11 doubles, 12 home runs and 16 walks.
• Ryan Mountcastle is hitting .255 with 14 doubles, four home runs and 11 walks.

Red Sox vs Orioles Head to Head

• 8/26/2025: 5-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/25/2025: 4-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/19/2025: 4-3 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/18/2025: 6-3 BAL (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/25/2025: 5-1 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/24/2025: 2-1 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 5/24/2025: 6-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/23/2025: 19-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/3/2025: 8-4 BOS (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/2/2025: 3-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!