Red Sox vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 25

Odds updated as of 6:12 p.m.

The MLB schedule on Monday includes the Boston Red Sox taking on the Baltimore Orioles.

We've got you covered, in terms of the vital information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Red Sox vs Orioles Game Info

• Boston Red Sox (71-60) vs. Baltimore Orioles (60-70)
• Date: Monday, August 25, 2025
• Time: 6:35 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and NESN

Red Sox vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-118) | BAL: (-100)
• Spread: BOS: -1.5 (+134) | BAL: +1.5 (-162)
• Total: 9.5 -- Over: (-100) | Under: (-122)

Red Sox vs Orioles Probable Starting Pitchers

Probable Pitchers: Brennan Bernardino (Red Sox) - 4-2, 2.93 ERA vs Tomoyuki Sugano (Orioles) - 10-5, 3.97 ERA

The Red Sox will give the nod to Brennan Bernardino (4-2, 2.93 ERA), who is eyeing win No. 5 on the season, and the Orioles will turn to Tomoyuki Sugano (10-5, 3.97 ERA). Bernardino and his team failed to cover the spread in his only opportunity this season as a starter. Bernardino's team lost his only start as a favorite this season. When Sugano starts, the Orioles have gone 14-10-0 against the spread. The Orioles have been the underdog on the moneyline in 14 of Sugano's starts this season, and they went 10-4 in those games.

Red Sox vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (56.9%)

Red Sox vs Orioles Moneyline

• Baltimore is the underdog, -100 on the moneyline, while Boston is a -118 favorite despite being on the road.

Red Sox vs Orioles Spread

• The Orioles are +1.5 on the spread (-162 to cover), and Boston is +134 to cover the runline.

Red Sox vs Orioles Over/Under

• An over/under of 9.5 has been set for Red Sox-Orioles on Aug. 25, with the over being -100 and the under -122.

Bet on Boston Red Sox vs. Baltimore Orioles on FanDuel today!

Red Sox vs Orioles Betting Trends

• The Red Sox have come away with 45 wins in the 78 contests they have been listed as the favorites in this season.
• This season Boston has been victorious 37 times in 61 chances when named as a favorite of at least -118 on the moneyline.
• The Red Sox and their opponents have gone over in 64 of their 130 games with a total set by sportsbooks this season.
• The Red Sox are 72-58-0 against the spread in their 130 games that had a posted line this season.
• The Orioles have won 32 of the 68 games they were listed as the moneyline underdog this season (47.1%).
• Baltimore has a 24-29 record (winning 45.3% of its games) when it has played as a moneyline underdog of -100 or longer.
• The Orioles have combined with opponents to go over the total 56 times this season for a 56-67-4 record against the over/under.
• The Orioles have a 59-68-0 record against the spread this season (covering 46.5% of the time).

Red Sox Player Leaders

• Jarren Duran leads Boston in OBP (.334), slugging percentage (.442) and total hits (131) this season. He has a .257 batting average.
• Among qualifying hitters in baseball, he is 84th in batting average, 68th in on-base percentage, and 74th in slugging.
• Trevor Story is hitting .260 with 22 doubles, 20 home runs and 28 walks, while slugging .427 with an on-base percentage of .307.
• His batting average is 71st among qualified players, his on-base percentage 118th, and his slugging percentage 82nd.
• Alex Bregman has collected 97 base hits, an OBP of .391 and a slugging percentage of .531 this season.
• Ceddanne Rafaela has 14 home runs, 53 RBI and a batting average of .249 this season.
• Rafaela heads into this matchup on a two-game hitting streak. In his last five games he is batting .176 with two doubles, a walk and an RBI.

Orioles Player Leaders

• Gunnar Henderson has totaled 131 hits with a .353 on-base percentage and a .471 slugging percentage, all club-highs for the Orioles. He's batting .283.
• Including all qualified hitters, he is 25th in batting average, while his on-base percentage is 37th and he is 42nd in slugging.
• Henderson hopes to build on a six-game hitting streak in this matchup. During his last 10 games he is hitting .275 with a double, a triple, two home runs, five walks and nine RBIs.
• Jackson Holliday has 17 doubles, two triples, 15 home runs and 37 walks while hitting .246. He's slugging .383 with an on-base percentage of .307.
• His batting average ranks 111th among all qualified players, his on-base percentage ranks 118th, and he is 127th in slugging.
• Colton Cowser is hitting .216 with 11 doubles, 11 home runs and 16 walks.
• Ryan Mountcastle is batting .259 with 14 doubles, four home runs and 11 walks.

Red Sox vs Orioles Head to Head

• 8/19/2025: 4-3 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/18/2025: 6-3 BAL (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/25/2025: 5-1 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/24/2025: 2-1 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 5/24/2025: 6-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/23/2025: 19-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/3/2025: 8-4 BOS (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/2/2025: 3-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 3/31/2025: 8-5 BAL (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/11/2024: 5-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)

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