Rays vs Blue Jays Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 16

Odds updated as of 7:11 p.m.

On Tuesday in MLB, the Tampa Bay Rays are playing the Toronto Blue Jays.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information about this game.

Rays vs Blue Jays Game Info

• Tampa Bay Rays (73-77) vs. Toronto Blue Jays (88-62)
• Date: Tuesday, September 16, 2025
• Time: 7:35 p.m. ET
• Venue: George M. Steinbrenner Field -- Tampa, Florida
• Coverage: FDSSUN and SNET

Rays vs Blue Jays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-110) | TOR: (-106)
• Spread: TB: +1.5 (-182) | TOR: -1.5 (+150)
• Total: 8 -- Over: (-110) | Under: (-110)

Rays vs Blue Jays Probable Starting Pitchers

Probable Pitchers: Ryan Pepiot (Rays) - 11-10, 3.59 ERA vs José Berrios (Blue Jays) - 9-5, 3.99 ERA

The Rays will give the ball to Ryan Pepiot (11-10, 3.59 ERA), who is eyeing win No. 12 on the season, and the Blue Jays will turn to Jose Berrios (9-5, 3.99 ERA). Pepiot and his team have a record of 10-18-0 against the spread when he starts. Pepiot's team is 9-5 this season when he starts and they are the moneyline favorite. When Berrios starts, the Blue Jays have gone 17-12-0 against the spread. The Blue Jays have been the moneyline underdog in 12 of Berrios' starts this season, and they went 9-3 in those games.

Rays vs Blue Jays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (52.4%)

Rays vs Blue Jays Moneyline

• Tampa Bay is a -110 favorite on the moneyline, while Toronto is a -106 underdog on the road.

Rays vs Blue Jays Spread

• The Blue Jays are 1.5-run favorites against the spread for this matchup with the Rays. The Blue Jays are +150 to cover, while the Rays are -182 to cover as a 1.5-run underdog on the runline.

Rays vs Blue Jays Over/Under

• A total of 8 runs has been set for the Rays-Blue Jays contest on Sept. 16, with the over available at -110 and the under at -110.

Bet on Tampa Bay Rays vs. Toronto Blue Jays on FanDuel today!

Rays vs Blue Jays Betting Trends

• The Rays have won in 39, or 56.5%, of the 69 contests they have been named as odds-on favorites in this year.
• This season Tampa Bay has been victorious 39 times in 69 chances when named as a favorite of at least -110 on the moneyline.
• The Rays and their opponents have gone over the total this season in 63 of their 145 opportunities.
• The Rays are 63-82-0 against the spread in their 145 games with a line set by sportsbooks this season.
• The Blue Jays have won 41 of the 73 games they were the underdog on the moneyline this season (56.2%).
• When playing as a moneyline underdog with odds of -106 or longer, Toronto has gone 36-32 (52.9%).
• The Blue Jays have had an over/under set by oddsmakers 149 times, and have combined with opponents to go over the total in 81 of those games (81-62-6).
• The Blue Jays have put together an 87-62-0 record against the spread this season (covering 58.4% of the time).

Rays Player Leaders

• Junior Caminero leads Tampa Bay with 148 hits, batting .260 this season with 72 extra-base hits. He has an on-base percentage of .301 and a slugging percentage of .541.
• He is 71st in batting average, 122nd in on-base percentage, and eighth in slugging among qualified hitters in baseball.
• Yandy Diaz is slashing .295/.356/.479 this season and leads the Rays with an OPS of .835.
• Among qualifying hitters, he ranks ninth in batting average, 27th in on-base percentage and 31st in slugging percentage.
• Diaz has picked up a hit in three straight games. During his last five outings he is hitting .421 with a double, two home runs, five walks and three RBIs.
• Brandon Lowe has collected 122 base hits, an OBP of .308 and a slugging percentage of .471 this season.
• Chandler Simpson has been key for Tampa Bay with 109 hits, an OBP of .324 plus a slugging percentage of .337.

Blue Jays Player Leaders

• Vladimir Guerrero Jr. has racked up an on-base percentage of .395, a team-best for the Blue Jays. He's batting .301 and slugging .490.
• Including all qualified hitters in the big leagues, his batting average places him sixth, his on-base percentage ranks third, and he is 24th in slugging.
• George Springer paces his team with 136 hits. He has a batting average of .302 while slugging .550 with an on-base percentage of .394.
• Including all qualifying hitters, he ranks fifth in batting average, fifth in on-base percentage and sixth in slugging percentage.
• Ernie Clement is batting .279 with 31 doubles, two triples, nine home runs and 24 walks.
• Alejandro Kirk is batting .291 with 17 doubles, 12 home runs and 45 walks.

Rays vs Blue Jays Head to Head

• 9/15/2025: 2-1 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/25/2025: 13-0 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/24/2025: 3-1 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/23/2025: 3-1 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 5/15/2025: 8-3 TB (Favorite: Blue Jays, Spread: -1.5, Total: 8, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 5/14/2025: 3-1 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/13/2025: 11-9 TB (Favorite: Blue Jays, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/22/2024: 4-3 TB (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/21/2024: 3-2 TB (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/20/2024: 1-0 TB (Favorite: Blue Jays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)

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