Rangers vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 16

Odds updated as of 7:12 p.m.

The MLB's Tuesday slate includes the Texas Rangers facing the Houston Astros.

We've got you covered, in terms of the most important info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Rangers vs Astros Game Info

• Texas Rangers (79-72) vs. Houston Astros (82-69)
• Date: Tuesday, September 16, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and RSN

Rangers vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TEX: (-118) | HOU: (-100)
• Spread: TEX: -1.5 (+140) | HOU: +1.5 (-170)
• Total: 7.5 -- Over: (-118) | Under: (-104)

Rangers vs Astros Probable Starting Pitchers

Probable Pitchers: Merrill Kelly (Rangers) - 12-7, 3.21 ERA vs A.J. Blubaugh (Astros) - 3-1, 2.45 ERA

The Rangers will give the ball to Merrill Kelly (12-7, 3.21 ERA), who is eyeing win No. 13 on the season, and the Astros will counter with A.J. Blubaugh (3-1, 2.45 ERA). Kelly's team is 14-13-0 against the spread in his starts this season. Kelly's team has been victorious in 58.8% of the games he's started as the moneyline favorite with a record of 10-7. Blubaugh has started only one game with a set spread, which the Astros failed to cover. The Astros have not been the underdog on the moneyline when Blubaugh starts this season.

Rangers vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rangers win (50.6%)

Rangers vs Astros Moneyline

• The moneyline numbers for Rangers vs. Astros reveal Texas as the favorite (-118) and Houston as the underdog (-100) despite being the home team.

Rangers vs Astros Spread

• The Rangers are 1.5-run road favorites on the runline against the Astros. The Rangers are +140 to cover, and the Astros are -170.

Rangers vs Astros Over/Under

• Rangers versus Astros on Sept. 16 has an over/under of 7.5 runs, with the odds on the over -118 and the under set at -104.

Bet on Texas Rangers vs. Houston Astros on FanDuel today!

Rangers vs Astros Betting Trends

• The Rangers have been favorites in 70 games this season and have come away with the win 45 times (64.3%) in those contests.
• Texas has a record of 41-21 in contests when bookmakers favor them by -118 or more on the moneyline.
• The Rangers and their opponents have hit the over in 67 of their 150 games with a total set by oddsmakers this season.
• In 150 games with a line this season, the Rangers have a mark of 82-68-0 against the spread.
• The Astros have won 56.6% of the games this season they were the underdog on the moneyline (30-23).
• Houston has a 20-17 record (winning 54.1% of its games) when it has played as a moneyline underdog of -100 or longer.
• The Astros have played in 150 games with an over/under set, and have combined with their opponents to go over the total 68 times (68-78-4).
• The Astros have put together a 75-75-0 record against the spread this season.

Rangers Player Leaders

• Wyatt Langford has 117 hits and an OBP of .344, both of which lead Texas hitters this season. He has a .245 batting average and a slugging percentage of .433.
• He is 98th in batting average, 44th in on-base percentage, and 74th in slugging among all qualifying batters in the majors.
• Josh Smith has an OPS of .714, fueled by an OBP of .343 and a team-best slugging percentage of .371 this season. He's batting .257.
• Among qualifying hitters, he ranks 75th in batting average, 48th in on-base percentage and 132nd in slugging percentage.
• Adolis Garcia has 112 hits this season and has a slash line of .231/.274/.401.
• Josh Jung has been key for Texas with 110 hits, an OBP of .294 plus a slugging percentage of .394.

Astros Player Leaders

• Jose Altuve has accumulated a slugging percentage of .440, a team-high for the Astros. He's batting .262 with an on-base percentage of .325.
• Including all qualifying hitters in MLB, his batting average places him 61st, his on-base percentage is 83rd, and he is 64th in slugging.
• Jeremy Pena's 143 hits and .357 on-base percentage are both team-highs. He has a batting average of .299 while slugging .462.
• Including all qualifying players, he ranks seventh in batting average, 23rd in on-base percentage and 44th in slugging percentage.
• Yainer Diaz has 22 doubles, a triple, 19 home runs and 20 walks while batting .257.
• Christian Walker is batting .237 with 23 doubles, a triple, 23 home runs and 40 walks.

Rangers vs Astros Head to Head

• 9/15/2025: 6-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/7/2025: 4-2 TEX (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/6/2025: 11-0 HOU (Favorite: Rangers, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/5/2025: 4-3 TEX (Favorite: Rangers, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/13/2025: 5-1 TEX (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/12/2025: 5-4 HOU (Favorite: Astros, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/11/2025: 7-3 TEX (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/18/2025: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/17/2025: 5-1 TEX (Favorite: Rangers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 5/16/2025: 6-3 HOU (Favorite: Rangers, Spread: -1.5, Total: 8, Favorite Moneyline: -198, Underdog Moneyline: +166)

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