Purdue vs Queens College Basketball Prediction, Odds, Picks, Best Bets for NCAA Tournament First Round

The No. 2 Purdue Boilermakers (27-8) and the No. 15 Queens Royals (21-13) battle on Friday for a spot in the second round of the NCAA Tournament. The first-round matchup starts at 7:35 p.m. ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Purdue vs. Queens Game Info and Odds

• Game day: Friday, March 20, 2026
• Game time: 7:35 p.m. ET
• TV channel: truTV
• Location: St. Louis, Missouri
• Arena: Enterprise Center

Check out these betting insights and trends before you wager on Friday's Purdue-Queens spread (Purdue -25.5) or over/under (159.5 points).

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Purdue vs. Queens: ATS Betting Stats and Trends

• Purdue has covered 15 times in 34 chances against the spread this season.
• Queens has put together a 16-16-0 record against the spread this year.
• Purdue covers the spread when it is a 25.5-point favorite or more 50% of the time. That's less often than Queens covers as an underdog of 25.5 or more (100%).
• Against the spread, the Boilermakers have performed worse when playing at home, covering five times in 17 home games, and six times in 11 road games.
• In 2025-26 against the spread, the Royals have a better winning percentage at home (.692, 9-4-0 record) than away (.312, 5-11-0).

Purdue vs. Queens: Moneyline Betting Stats

• Purdue has been victorious in 20, or 74.1%, of the 27 contests it has been chosen as moneyline favorites in this season.
• The Boilermakers have been listed as a favorite of -10000 or more on two occasions this season and won both games.
• Queens has gone 3-9 in games it was the underdog on the moneyline (winning 25% of those games).
• The Royals have not yet played as a moneyline underdog of +3000 or longer.
• The moneyline set for this matchup implies Purdue has a 99% chance of walking away with the win.

Purdue vs. Queens Head-to-Head Comparison

• Purdue has a +403 scoring differential, topping opponents by 11.6 points per game. It is putting up 81.7 points per game to rank 54th in college basketball and is giving up 70.1 per contest to rank 70th in college basketball.
• Purdue's leading scorer, Braden Smith, ranks 403rd in the country averaging 14.0 points per game.
• Queens' +66 scoring differential (outscoring opponents by 2.0 points per game) is a result of putting up 84.9 points per game (18th in college basketball) while giving up 82.9 per contest (353rd in college basketball).
• Nasir Mann is 502nd in the country with a team-leading 13.4 points per game.
• The Boilermakers are 120th in the nation at 32.9 rebounds per game. That's 6.8 more than the 26.1 their opponents average.
• Trey Kaufman-Renn paces the Boilermakers with 8.5 rebounds per game (51st in college basketball action).
• The Royals rank 239th in the country at 31.0 rebounds per game. That's similar to the 31.4 their opponents average.
• Mann leads the Royals with 5.8 rebounds per game (327th in college basketball).
• Purdue ranks third in college basketball with 110.4 points scored per 100 possessions, and 166th in college basketball defensively with 94.8 points conceded per 100 possessions.
• The Royals average 105.6 points per 100 possessions on offense (31st in college basketball), and give up 103.2 points per 100 possessions (345th in college basketball).

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