Purdue vs Miami (FL) College Basketball Prediction, Odds, Picks, Best Bets for NCAA Tournament Second Round

The No. 2 seed Purdue Boilermakers (28-8) and the No. 7 seed Miami Hurricanes (26-8) will square off in the NCAA Tournament with a spot in the Sweet 16 of the West Region bracket up for grabs on Sunday at Enterprise Center, tipping off at 12:10 p.m. ET.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Purdue vs. Miami (FL) Game Info and Odds

• Game day: Sunday, March 22, 2026
• Game time: 12:10 p.m. ET
• TV channel: CBS
• Location: St. Louis, Missouri
• Arena: Enterprise Center

Purdue vs. Miami (FL) Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Purdue win (68.8%)

Before you bet on Sunday's Purdue-Miami (FL) spread (Purdue -7.5) or total (147.5 points), check out the betting insights and trends below.

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Purdue vs. Miami (FL): ATS Betting Stats and Trends

• Purdue has won 16 games against the spread this season, while failing to cover 19 times.
• Miami (FL) has put together a 19-15-0 record against the spread this season.
• As a 7.5-point underdog or more in 2025-26, Miami (FL) is 1-2 against the spread compared to the 9-12 ATS record Purdue puts up as a 7.5-point favorite.
• The Boilermakers have covered the spread in a lower percentage of their home games than road games. They have covered five times in 17 games at home, and they've covered six times in 11 games on the road.
• The Hurricanes have been better against the spread on the road (8-2-0) than at home (8-10-0) this year.

Purdue vs. Miami (FL): Moneyline Betting Stats

• Purdue has been chosen as the moneyline favorite in 28 games this year and has walked away with the win 21 times (75%) in those games.
• This season, the Boilermakers have come away with a win 16 times in 17 chances when named as a favorite of at least -360 or better on the moneyline.
• Miami (FL) has gone 6-5 in games it was the underdog on the moneyline (winning 54.5% of those games).
• The Hurricanes have played as a moneyline underdog of +280 or longer in only two games this season, which they lost both.
• Oddsmakers have implied with the moneyline set for this matchup that Purdue has a 78.3% chance of pulling out a win.

Purdue vs. Miami (FL) Head-to-Head Comparison

• At 77.3 points scored per game and 70.4 points allowed last season, Purdue was 82nd in the nation on offense and 126th on defense.
• On the glass, Purdue was 300th in the country in rebounds (29.9 per game) last year. It was 28th in rebounds allowed (28.2 per game).
• At 15.9 assists per game last season, Purdue was 42nd in the nation.
• Purdue committed 9.9 turnovers per game last year and forced 11.3 per game, ranking 62nd and 176th, respectively, in the nation.
• Miami (FL) ranked 167th in college basketball with 74 points per game last year, but on defense it struggled, surrendering 80.6 points per game (eighth-worst in college basketball).
• Last season Miami (FL) pulled down 29.2 boards per game (325th-ranked in college basketball) and gave up 30.5 rebounds per contest (135th-ranked).
• Miami (FL) put up 12.9 dimes per game, which ranked them 227th in the nation.
• Miami (FL) averaged 10.2 turnovers per game (87th-ranked in college basketball) this year, while forcing 9.9 turnovers per contest (312th-ranked).

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