Pirates vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for July 18

Odds updated as of 6:11 p.m.

On Friday in MLB, the Pittsburgh Pirates are up against the Chicago White Sox.

We've got you covered, in terms of the most important info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Pirates vs White Sox Game Info

• Pittsburgh Pirates (39-58) vs. Chicago White Sox (32-65)
• Date: Friday, July 18, 2025
• Time: 6:40 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and CHSN

Pirates vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-158) | CHW: (+134)
• Spread: PIT: -1.5 (+138) | CHW: +1.5 (-166)
• Total: 8.5 -- Over: (-114) | Under: (-106)

Pirates vs White Sox Probable Starting Pitchers

Probable Pitchers: Bailey Falter (Pirates) - 6-4, 3.79 ERA vs Jonathan Cannon (White Sox) - 3-7, 4.44 ERA

The Pirates will give the nod to Bailey Falter (6-4) against the White Sox and Jonathan Cannon (3-7). When Falter starts, his team is 11-6-0 against the spread this season. When Falter starts a game and his team is the favorite on the moneyline, they have a record of 3-1. When Cannon starts, the White Sox have gone 6-7-0 against the spread. The White Sox have been the moneyline underdog in 13 of Cannon's starts this season, and they went 4-9 in those games.

Pirates vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (56%)

Pirates vs White Sox Moneyline

• Chicago is the underdog, +134 on the moneyline, while Pittsburgh is a -158 favorite at home.

Pirates vs White Sox Spread

• The Pirates are favored by 1.5 runs at home versus the White Sox. The Pirates are +138 to cover the spread, while the White Sox are -166.

Pirates vs White Sox Over/Under

• An over/under of 8.5 has been set for Pirates-White Sox on July 18, with the over being -114 and the under -106.

Bet on Pittsburgh Pirates vs. Chicago White Sox on FanDuel today!

Pirates vs White Sox Betting Trends

• The Pirates have been victorious in 11, or 50%, of the 22 contests they have been chosen as favorites in this season.
• Pittsburgh has a record of 1-2 when favored by -158 or more this year.
• The Pirates' games have gone over the total in 34 of their 90 opportunities.
• In 90 games with a line this season, the Pirates have a mark of 46-44-0 against the spread.
• The White Sox have been the underdog on the moneyline 91 total times this season. They've finished 29-62 in those games.
• Chicago has a 19-46 record (winning only 29.2% of its games) when playing as a moneyline underdog of +134 or longer.
• The White Sox have combined with opponents to hit the over on the total 40 times this season for a 40-49-5 record against the over/under.
• The White Sox have a 50-44-0 record ATS this season (covering 53.2% of the time).

Pirates Player Leaders

• Oneil Cruz has 65 hits, which ranks first among Pittsburgh hitters this season, while batting .212 with 29 extra-base hits. He has an on-base percentage of .319 and a slugging percentage of .414.
• Among all qualified hitters in MLB, his batting average ranks 146th, his on-base percentage ranks 99th, and he is 92nd in slugging.
• Cruz hopes to build on a five-game hitting streak in this matchup. In his last five games he is hitting .375 with a double, a home run, a walk and two RBIs.
• Andrew McCutchen has 77 hits this season and a team-best OBP of .335. He's batting .255 and slugging .381.
• Among qualified hitters, his batting average ranks him 88th, his on-base percentage 72nd, and his slugging percentage 118th.
• Bryan Reynolds has an OPS of .656, fueled by an OBP of .287 and a team-best slugging percentage of .369 this season.
• Reynolds takes a two-game hitting streak into this matchup. During his last five outings he is hitting .158 with a double and an RBI.
• Isiah Kiner-Falefa has been key for Pittsburgh with 76 hits, an OBP of .318 plus a slugging percentage of .339.

White Sox Player Leaders

• Miguel Vargas has accumulated a team-best OBP (.297), and paces the White Sox in hits (74). He's batting .218 and slugging.
• Including all the qualified players in the big leagues, his batting average ranks 142nd, his on-base percentage ranks 132nd, and he is 116th in slugging.
• Andrew Benintendi has 10 doubles, two triples, 11 home runs and 22 walks while batting .233. He's slugging .429 with an on-base percentage of .297.
• Chase Meidroth is batting .243 with seven doubles, two home runs and 32 walks.
• Lenyn Sosa paces his team with a .417 slugging percentage.

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