Pirates vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for July 18

Odds updated as of 4:12 a.m.

The MLB slate on Friday includes the Pittsburgh Pirates facing the Chicago White Sox.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Pirates vs White Sox Game Info

• Pittsburgh Pirates (39-58) vs. Chicago White Sox (32-65)
• Date: Friday, July 18, 2025
• Time: 6:40 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and CHSN

Pirates vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-164) | CHW: (+138)
• Spread: PIT: -1.5 (+130) | CHW: +1.5 (-156)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Pirates vs White Sox Probable Starting Pitchers

Probable Pitchers: Bailey Falter (Pirates) - 6-4, 3.79 ERA vs Jonathan Cannon (White Sox) - 3-7, 4.44 ERA

The Pirates will give the nod to Bailey Falter (6-4) versus the White Sox and Jonathan Cannon (3-7). Falter and his team have a record of 11-6-0 against the spread when he starts. Falter's team has won 75% of his starts when they are favored on the moneyline (3-1). The White Sox are 6-7-0 against the spread when Cannon starts. The White Sox are 4-9 in Cannon's 13 starts this season that they were the moneyline underdog.

Pirates vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (54.2%)

Pirates vs White Sox Moneyline

• The Pirates vs White Sox moneyline has Pittsburgh as a -164 favorite, while Chicago is a +138 underdog on the road.

Pirates vs White Sox Spread

• The White Sox are +1.5 on the spread (-156 to cover), and Pittsburgh is +130 to cover the runline.

Pirates vs White Sox Over/Under

• Pirates versus White Sox on July 18 has an over/under of 8.5 runs, with the odds on the over -115 and the under set at -105.

Bet on Pittsburgh Pirates vs. Chicago White Sox on FanDuel today!

Pirates vs White Sox Betting Trends

• The Pirates have come away with 11 wins in the 22 contests they have been listed as the favorites in this season.
• Pittsburgh has been listed as a favorite of -164 or more on two occasions this season and split those games.
• The Pirates and their opponents have gone over in 34 of their 90 games with a total set by sportsbooks this season.
• The Pirates have an against the spread mark of 46-44-0 in 90 games with a line this season.
• The White Sox are 29-62 in games they were the underdog on the moneyline (winning 31.9% of those games).
• In games it has played as a moneyline underdog with odds of +138 or longer, Chicago has a record of 15-42 (26.3%).
• In the 94 games bookmakers have set an over/under for the White Sox, they have combined with opponents to go over the total 40 times (40-49-5).
• The White Sox have collected a 50-44-0 record against the spread this season (covering 53.2% of the time).

Pirates Player Leaders

• Oneil Cruz leads Pittsburgh in total hits (65) this season while batting .212 with 29 extra-base hits. He has an on-base percentage of .319 and a slugging percentage of .414.
• Among qualifying batters in baseball, his batting average ranks 146th, his on-base percentage ranks 99th, and he is 92nd in slugging.
• Cruz hopes to build on a five-game hitting streak in this matchup. During his last five outings he is hitting .375 with a double, a home run, a walk and two RBIs.
• Andrew McCutchen has 77 hits this season and a team-best OBP of .335. He's batting .255 and slugging .381.
• Among all qualified, he is 88th in batting average, 72nd in on-base percentage and 118th in slugging percentage.
• Bryan Reynolds leads Pittsburgh in slugging percentage (.369) powered by 29 extra-base hits.
• Reynolds takes a two-game hitting streak into this matchup. During his last five outings he is hitting .158 with a double and an RBI.
• Isiah Kiner-Falefa has one home run, 23 RBI and a batting average of .274 this season.

White Sox Player Leaders

• Miguel Vargas has racked up an on-base percentage of .297 and has 74 hits, both team-best numbers for the White Sox. He's batting .218 and slugging .383.
• Including all qualified hitters in the big leagues, he ranks 142nd in batting average, 132nd in on-base percentage and 116th in slugging percentage.
• Andrew Benintendi has 10 doubles, two triples, 11 home runs and 22 walks while hitting .233. He's slugging .429 with an on-base percentage of .297.
• Chase Meidroth has seven doubles, two home runs and 32 walks while hitting .243.
• Lenyn Sosa's .417 slugging percentage leads his team.

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