Padres vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 5

Odds updated as of 8:12 p.m.

The MLB schedule on Friday includes the San Diego Padres taking on the Colorado Rockies.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information about this matchup.

Padres vs Rockies Game Info

• San Diego Padres (76-64) vs. Colorado Rockies (39-101)
• Date: Friday, September 5, 2025
• Time: 8:40 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: COLR and SDPA

Padres vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-220) | COL: (+184)
• Spread: SD: -1.5 (-152) | COL: +1.5 (+126)
• Total: 10.5 -- Over: (-112) | Under: (-108)

Padres vs Rockies Probable Starting Pitchers

Probable Pitchers: Nick Pivetta (Padres) - 13-4, 2.84 ERA vs Kyle Freeland (Rockies) - 3-14, 5.41 ERA

The Padres will give the ball to Nick Pivetta (13-4, 2.84 ERA), who is eyeing win No. 14 on the season, and the Rockies will counter with Kyle Freeland (3-14, 5.41 ERA). Pivetta's team is 16-11-0 against the spread in his starts this season. Pivetta's team has a record of 11-6 this season when he starts and they are the favorite on the moneyline. The Rockies have gone 10-15-0 ATS in Freeland's 25 starts that had a set spread. The Rockies have a 6-18 record in Freeland's 24 starts this season when they were the underdog on the moneyline.

Padres vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (70.3%)

Padres vs Rockies Moneyline

• San Diego is the favorite, -220 on the moneyline, while Colorado is a +184 underdog despite being at home.

Padres vs Rockies Spread

• The Rockies are +1.5 on the run line against the Padres. The Rockies are +126 to cover, and the Padres are -152.

Padres vs Rockies Over/Under

• An over/under of 10.5 has been set for Padres-Rockies on Sept. 5, with the over being -112 and the under -108.

Bet on San Diego Padres vs. Colorado Rockies on FanDuel today!

Padres vs Rockies Betting Trends

• The Padres have been favorites in 72 games this season and have come away with the win 43 times (59.7%) in those contests.
• San Diego has a record of 3-2 when favored by -220 or more this year.
• The Padres and their opponents have hit the over in 61 of their 138 games with a total set by oddsmakers this season.
• In 138 games with a line this season, the Padres have a mark of 75-63-0 against the spread.
• The Rockies have won 35 of the 132 games they were the underdog on the moneyline this season (26.5%).
• In games it has played as a moneyline underdog with odds of +184 or longer, Colorado has a 14-55 record (winning just 20.3% of its games).
• The Rockies have combined with opponents to go over the total 59 times this season for a 59-73-4 record against the over/under.
• The Rockies have collected a 56-80-0 record ATS this season.

Padres Player Leaders

• Fernando Tatis Jr. is batting .262 with 27 doubles, two triples, 19 home runs and 82 walks. He has an on-base percentage of .368 while slugging .431.
• Among all qualifying hitters in the majors, his batting average ranks 67th, his on-base percentage ranks 14th, and he is 79th in slugging.
• Manny Machado has 153 hits, which ranks first among San Diego batters this season. He's batting .283 with 54 extra-base hits. He's also slugging .465 with an on-base percentage of .344.
• Among qualified hitters, his batting average ranks him 21st, his on-base percentage 49th, and his slugging percentage 50th.
• Machado has picked up a hit in two straight games. In his last five games he is batting .222 with a home run, two walks and three RBIs.
• Luis Arraez has hit seven homers with a team-high .391 SLG this season.
• Arraez brings a six-game hitting streak into this matchup. In his last 10 outings he is hitting .250 with a double, a home run, a walk and five RBIs.
• Ramon Laureano has been key for San Diego with 112 hits, an OBP of .361 plus a slugging percentage of .543.
• Laureano has hit safely in five games in a row. During his last five outings he is batting .421 with a home run, two walks and four RBIs.

Rockies Player Leaders

• Hunter Goodman has racked up a slugging percentage of .526 and has 129 hits, both team-high marks for the Rockies. He's batting .280 and with an on-base percentage of .326.
• Including all the qualifying hitters in MLB, he ranks 24th in batting average, 86th in on-base percentage and 13th in slugging percentage.
• Mickey Moniak has 17 doubles, eight triples, 18 home runs and 19 walks while batting .262. He's slugging .500 with an on-base percentage of .300.
• Jordan Beck a has .331 on-base percentage to lead the Rockies.
• Brenton Doyle is batting .247 with 19 doubles, two triples, 14 home runs and 29 walks.

Padres vs Rockies Head to Head

• 5/11/2025: 9-3 COL (Favorite: Padres, Spread: -1.5, Total: 11.5, Favorite Moneyline: -310, Underdog Moneyline: +250)
• 5/10/2025: 21-0 SD (Favorite: Padres, Spread: -1.5, Total: 12, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 5/9/2025: 13-9 SD (Favorite: Padres, Spread: -1.5, Total: 11.5, Favorite Moneyline: -176, Underdog Moneyline: +148)
• 4/13/2025: 6-0 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 4/12/2025: 2-0 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 4/11/2025: 8-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 8/18/2024: 3-2 COL (Favorite: Padres, Spread: -1.5, Total: 11.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 8/17/2024: 8-3 SD (Favorite: Padres, Spread: -1.5, Total: 10.5, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 8/16/2024: 7-3 COL (Favorite: Padres, Spread: -1.5, Total: 11.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 8/4/2024: 10-2 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)

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