Padres vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for July 18

Odds updated as of 6:11 a.m.

Friday's slate in the MLB includes a matchup between the San Diego Padres and the Washington Nationals.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Padres vs Nationals Game Info

• San Diego Padres (52-44) vs. Washington Nationals (38-58)
• Date: Friday, July 18, 2025
• Time: 6:45 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: MASN and SDPA

Padres vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-156) | WSH: (+132)
• Spread: SD: -1.5 (+106) | WSH: +1.5 (-128)
• Total: 8.5 -- Over: (-114) | Under: (-106)

Padres vs Nationals Probable Starting Pitchers

Probable Pitchers: Dylan Cease (Padres) - 3-9, 4.88 ERA vs Mike Soroka (Nationals) - 3-7, 5.35 ERA

The Padres will call on Dylan Cease (3-9) versus the Nationals and Mike Soroka (3-7). Cease and his team have a record of 8-11-0 against the spread when he starts. When Cease starts a game and his team is the favorite on the moneyline, they have a record of 7-5. The Nationals have a 5-8-0 ATS record in Soroka's 13 starts that had a set spread. The Nationals are 3-9 in Soroka's 12 starts this season that they were the underdog on the moneyline.

Padres vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (57.3%)

Padres vs Nationals Moneyline

• Washington is a +132 underdog on the moneyline, while San Diego is a -156 favorite on the road.

Padres vs Nationals Spread

• The Nationals are at +1.5 on the runline against the Padres. The Nationals are -128 to cover the spread, and the Padres are +106.

Padres vs Nationals Over/Under

• The over/under for Padres-Nationals on July 18 is 8.5. The over is -114, and the under is -106.

Bet on San Diego Padres vs. Washington Nationals on FanDuel today!

Padres vs Nationals Betting Trends

• The Padres have won in 28, or 59.6%, of the 47 contests they have been named as odds-on favorites in this year.
• This season San Diego has come away with a win 14 times in 23 chances when named as a favorite of at least -156 on the moneyline.
• Contests with the Padres have gone over the total set by oddsmakers in 39 of 95 chances this season.
• The Padres have an against the spread record of 51-44-0 in 95 games with a line this season.
• The Nationals have won 33 of the 73 games they were listed as the moneyline underdog this season (45.2%).
• When it has played as a moneyline underdog with odds of +132 or longer, Washington has a 16-23 record (winning 41% of its games).
• The Nationals have had an over/under set by oddsmakers 91 times, and have combined with opponents to go over the total in 51 of those games (51-38-2).
• The Nationals have gone 47-44-0 ATS this season.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego with an OBP of .366 this season while batting .269 with 51 walks and 65 runs scored. He has a slugging percentage of .451.
• Among all qualified batters in the majors, he ranks 60th in batting average, 27th in on-base percentage, and 62nd in slugging.
• Tatis hopes to build on a six-game hitting streak in this matchup. In his last 10 outings he is batting .343 with two doubles, a triple, a home run, 10 walks and four RBIs.
• Manny Machado leads San Diego with 107 hits and a team-best slugging percentage of .490. He's batting .292 with an on-base percentage of .350.
• He ranks 17th in batting average, 49th in on-base percentage and 27th in slugging in the major leagues.
• Luis Arraez has 102 hits this season and has a slash line of .279/.314/.389.
• Gavin Sheets has 14 home runs, 50 RBI and a batting average of .265 this season.

Nationals Player Leaders

• James Wood has a team-best OBP (.381) and slugging percentage (.534), while leading the Nationals in hits (99, while batting .278).
• Including all qualifying players in the big leagues, he is 45th in batting average, 12th in on-base percentage and 14th in slugging percentage.
• C.J. Abrams is hitting .287 with 20 doubles, four triples, 12 home runs and 24 walks. He's slugging .483 with an on-base percentage of .353.
• Including all qualifying players, he is 22nd in batting average, 44th in on-base percentage and 32nd in slugging percentage.
• Luis Garcia is batting .259 with 20 doubles, seven home runs and 18 walks.
• Nathaniel Lowe has 14 doubles, two triples, 14 home runs and 34 walks while batting .227.

Padres vs Nationals Head to Head

• 6/25/2025: 1-0 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/24/2025: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 6/23/2025: 10-6 WSH (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 7/25/2024: 3-0 SD (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 7/24/2024: 12-3 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 7/23/2024: 4-0 SD (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/26/2024: 8-5 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 6/25/2024: 9-7 SD (Favorite: Nationals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/24/2024: 7-6 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/25/2023: 8-3 WSH (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -215, Underdog Moneyline: +180)

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