Padres vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for July 18

Odds updated as of 6:11 p.m.
On Friday in MLB, the San Diego Padres are playing the Washington Nationals.
Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.
Padres vs Nationals Game Info
- San Diego Padres (52-44) vs. Washington Nationals (38-58)
- Date: Friday, July 18, 2025
- Time: 6:45 p.m. ET
- Venue: Nationals Park -- Washington, District of Columbia
- Coverage: MASN and SDPA
Padres vs Nationals Odds & Moneyline
- All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: SD: (-152) | WSH: (+128)
- Spread: SD: -1.5 (+112) | WSH: +1.5 (-134)
- Total: 8.5 -- Over: (-100) | Under: (-122)
Padres vs Nationals Probable Starting Pitchers
Probable Pitchers: Dylan Cease (Padres) - 3-9, 4.88 ERA vs Mike Soroka (Nationals) - 3-7, 5.35 ERA
The Padres will give the nod to Dylan Cease (3-9, 4.88 ERA), who is eyeing win No. 4 on the season, and the Nationals will turn to Mike Soroka (3-7, 5.35 ERA). Cease's team is 8-11-0 against the spread in his starts this season. Cease's team has a record of 7-5 this season when he starts and they are the favorite on the moneyline. When Soroka starts, the Nationals have gone 5-8-0 against the spread. The Nationals have a 3-9 record in Soroka's 12 starts this season when they were the moneyline underdog.
Padres vs Nationals Prediction & Pick
All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (55.6%)
Padres vs Nationals Moneyline
- San Diego is a -152 favorite on the moneyline, while Washington is a +128 underdog at home.
Padres vs Nationals Spread
- The Padres are 1.5-run road favorites on the runline against the Nationals. The Padres are +112 to cover, and the Nationals are -134.
Padres vs Nationals Over/Under
- A total of 8.5 runs has been set for the Padres-Nationals contest on July 18, with the over available at -100 and the under at -122.
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Padres vs Nationals Betting Trends
- The Padres have come away with 28 wins in the 47 contests they have been listed as the favorites in this season.
- This year San Diego has won 15 of 24 games when listed as at least -152 on the moneyline.
- The Padres' games have gone over the total in 39 of their 95 opportunities.
- The Padres are 51-44-0 against the spread in their 95 games that had a posted line this season.
- The Nationals have won 45.2% of the games this season they were the moneyline underdog (33-40).
- Washington has gone 17-26 when it has played as a moneyline underdog with odds of +128 or longer (39.5%).
- The Nationals have played in 91 games with an over/under set, and have combined with opponents to go over the total 51 times (51-38-2).
- The Nationals have gone 47-44-0 against the spread this season.
Padres Player Leaders
- Fernando Tatis Jr. leads San Diego with an OBP of .366 this season while batting .269 with 51 walks and 65 runs scored. He has a slugging percentage of .451.
- Among qualified hitters in baseball, his batting average ranks 60th, his on-base percentage ranks 27th, and he is 62nd in slugging.
- Tatis will look for his seventh straight game with a hit in this contest. During his last 10 outings he is batting .343 with two doubles, a triple, a home run, 10 walks and four RBIs.
- Manny Machado leads San Diego in slugging percentage (.490) and total hits (107) this season. He's batting .292 with an on-base percentage of .350.
- He is 17th in batting average, 49th in on-base percentage and 27th in slugging among qualifying hitters.
- Luis Arraez is batting .279 with a .389 slugging percentage and 35 RBI this year.
- Gavin Sheets has 14 home runs, 50 RBI and a batting average of .265 this season.
Nationals Player Leaders
- James Wood has racked up a team-best OBP (.381) and slugging percentage (.534), while leading the Nationals in hits (99, while batting .278).
- Including all the qualified players in the majors, his batting average ranks 45th, his on-base percentage ranks 12th, and he is 14th in slugging.
- C.J. Abrams is batting .287 with 20 doubles, four triples, 12 home runs and 24 walks. He's slugging .483 with an on-base percentage of .353.
- Including all qualifying hitters, his batting average puts him 22nd, his on-base percentage ranks 44th, and he is 32nd in slugging.
- Luis Garcia is batting .259 with 20 doubles, seven home runs and 18 walks.
- Nathaniel Lowe is hitting .227 with 14 doubles, two triples, 14 home runs and 34 walks.
Padres vs Nationals Head to Head
- 6/25/2025: 1-0 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
- 6/24/2025: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
- 6/23/2025: 10-6 WSH (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
- 7/25/2024: 3-0 SD (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
- 7/24/2024: 12-3 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
- 7/23/2024: 4-0 SD (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
- 6/26/2024: 8-5 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
- 6/25/2024: 9-7 SD (Favorite: Nationals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
- 6/24/2024: 7-6 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
- 6/25/2023: 8-3 WSH (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -215, Underdog Moneyline: +180)
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