Padres vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for July 23

Odds updated as of 11:11 a.m.

The San Diego Padres versus the Miami Marlins is on the MLB schedule for Wednesday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info about this game.

Padres vs Marlins Game Info

• San Diego Padres (55-46) vs. Miami Marlins (47-53)
• Date: Wednesday, July 23, 2025
• Time: 12:10 p.m. ET
• Venue: loanDepot park -- Miami, Florida
• Coverage: FDSFL and SDPA

Padres vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-146) | MIA: (+124)
• Spread: SD: -1.5 (+110) | MIA: +1.5 (-132)
• Total: 7.5 -- Over: (-120) | Under: (-102)

Padres vs Marlins Probable Starting Pitchers

Probable Pitchers: Dylan Cease (Padres) - 3-9, 4.64 ERA vs Sandy Alcantara (Marlins) - 4-9, 7.14 ERA

The Padres will look to Dylan Cease (3-9) against the Marlins and Sandy Alcantara (4-9). When Cease starts, his team is 9-11-0 against the spread this season. Cease's team has a record of 8-5 this season when he starts and they are the favorite on the moneyline. When Alcantara starts, the Marlins are 8-11-0 against the spread. The Marlins are 7-9 in Alcantara's 16 starts this season that they were the moneyline underdog.

Padres vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (60.4%)

Padres vs Marlins Moneyline

• The Padres vs Marlins moneyline has San Diego as a -146 favorite, while Miami is a +124 underdog at home.

Padres vs Marlins Spread

• The Padres are favored by 1.5 runs on the road versus the Marlins. The Padres are +110 to cover the spread, while the Marlins are -132.

Padres vs Marlins Over/Under

• An over/under of 7.5 has been set for Padres-Marlins on July 23, with the over being -120 and the under -102.

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Padres vs Marlins Betting Trends

• The Padres have been chosen as favorites in 49 games this year and have walked away with the win 30 times (61.2%) in those games.
• This year San Diego has won 18 of 27 games when listed as at least -146 on the moneyline.
• The Padres and their opponents have hit the over in 41 of their 99 games with a total set by oddsmakers this season.
• The Padres have an against the spread mark of 55-44-0 in 99 games with a line this season.
• The Marlins are 39-45 in games they were listed as the moneyline underdog (winning 46.4% of those games).
• Miami has a record of 23-26 in games it has played as a moneyline underdog with odds of +124 or longer (46.9%).
• The Marlins have played in 96 games with an over/under set, and have combined with their opponents to go over the total 45 times (45-51-0).
• The Marlins have collected a 56-40-0 record ATS this season (covering 58.3% of the time).

Padres Player Leaders

• Manny Machado leads San Diego with 109 hits, batting .282 this season with 41 extra-base hits. He has an on-base percentage of .344 and a slugging percentage of .482.
• Among qualifying batters, he ranks 30th in batting average, his on-base percentage ranks 58th, and he is 31st in slugging.
• Fernando Tatis Jr. leads San Diego with an OBP of .362 this season while batting .262 with 55 walks and 67 runs scored. He's slugging .439.
• He is 74th in batting average, 30th in on-base percentage and 69th in slugging in MLB.
• Luis Arraez has an OPS of .713, fueled by an OBP of .320 and a team-best slugging percentage of .392 this season.
• Arraez enters this game with five games in a row with at least one hit. During his last five outings he is batting .400 with a double, a walk and two RBIs.
• Xander Bogaerts has been key for San Diego with 94 hits, an OBP of .345 plus a slugging percentage of .382.
• Bogaerts takes a three-game hitting streak into this game. In his last five games he is hitting .300 with three doubles, a home run, two walks and four RBIs.

Marlins Player Leaders

• Kyle Stowers has accumulated 95 hits with a .372 on-base percentage, leading the Marlins in both categories. He's batting .295 and slugging .565.
• He ranks ninth in batting average, 19th in on-base percentage and sixth in slugging percentage among all qualifying batters in the majors.
• Otto Lopez is hitting .252 with 11 doubles, 11 home runs and 33 walks. He's slugging .392 with an on-base percentage of .326.
• Including all qualified hitters, he ranks 99th in batting average, 79th in on-base percentage and 114th in slugging percentage.
• Xavier Edwards has a .356 slugging percentage, which paces the Marlins.
• Agustin Ramirez is hitting .244 with 22 doubles, a triple, 14 home runs and 19 walks.

Padres vs Marlins Head to Head

• 7/22/2025: 4-3 MIA (Favorite: Marlins, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/21/2025: 2-1 SD (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/28/2025: 10-8 MIA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/27/2025: 8-6 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/26/2025: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/11/2024: 7-6 MIA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 8/10/2024: 9-8 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 8/9/2024: 6-2 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/29/2024: 9-1 MIA (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 5/28/2024: 4-0 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)

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