Padres vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for July 23

Odds updated as of 9:12 a.m.

Wednesday's slate in the MLB includes a matchup between the San Diego Padres and the Miami Marlins.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this matchup.

Padres vs Marlins Game Info

• San Diego Padres (55-46) vs. Miami Marlins (47-53)
• Date: Wednesday, July 23, 2025
• Time: 12:10 p.m. ET
• Venue: loanDepot park -- Miami, Florida
• Coverage: FDSFL and SDPA

Padres vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-146) | MIA: (+124)
• Spread: SD: -1.5 (+118) | MIA: +1.5 (-142)
• Total: 8 -- Over: (-105) | Under: (-115)

Padres vs Marlins Probable Starting Pitchers

Probable Pitchers: Dylan Cease (Padres) - 3-9, 4.64 ERA vs Sandy Alcantara (Marlins) - 4-9, 7.14 ERA

The Padres will give the nod to Dylan Cease (3-9) against the Marlins and Sandy Alcantara (4-9). Cease's team is 9-11-0 against the spread this season in his starts. Cease's team has won 61.5% of his starts when they are favored on the moneyline (8-5). The Marlins have an 8-11-0 record against the spread in Alcantara's starts. The Marlins are 7-9 in Alcantara's 16 starts this season that they were the moneyline underdog.

Padres vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (60.4%)

Padres vs Marlins Moneyline

• Miami is a +124 underdog on the moneyline, while San Diego is a -146 favorite on the road.

Padres vs Marlins Spread

• The Padres are 1.5-run road favorites on the runline against the Marlins. The Padres are +118 to cover, and the Marlins are -142.

Padres vs Marlins Over/Under

• A combined run total of 8 has been set for Padres-Marlins on July 23, with the over at -105 and the under at -115.

Bet on San Diego Padres vs. Miami Marlins on FanDuel today!

Padres vs Marlins Betting Trends

• The Padres have come away with 30 wins in the 49 contests they have been listed as the favorites in this season.
• This season San Diego has been victorious 18 times in 27 chances when named as a favorite of at least -146 on the moneyline.
• The Padres and their opponents have gone over in 41 of their 99 games with a total set by sportsbooks this season.
• The Padres have an against the spread record of 55-44-0 in 99 games with a line this season.
• The Marlins have won 46.4% of the games this season they were the underdog on the moneyline (39-45).
• Miami has gone 23-26 when it has played as a moneyline underdog with odds of +124 or longer (46.9%).
• In the 96 games bookmakers have set an over/under for the Marlins, they have combined with opponents to go over the total 45 times (45-51-0).
• The Marlins have a 56-40-0 record against the spread this season (covering 58.3% of the time).

Padres Player Leaders

• Manny Machado leads San Diego with 109 hits, batting .282 this season with 41 extra-base hits. He has an on-base percentage of .344 and a slugging percentage of .482.
• Among qualified hitters in the majors, he ranks 30th in batting average, 58th in on-base percentage, and 31st in slugging.
• Fernando Tatis Jr. leads San Diego with an OBP of .362 this season while batting .262 with 55 walks and 67 runs scored. He's slugging .439.
• His batting average is 74th among qualified players, his on-base percentage 30th, and his slugging percentage 69th.
• Luis Arraez has hit five homers with a team-high .392 SLG this season.
• Arraez takes a five-game hitting streak into this matchup. In his last five games he is batting .400 with a double, a walk and two RBIs.
• Xander Bogaerts has been key for San Diego with 94 hits, an OBP of .345 plus a slugging percentage of .382.
• Bogaerts brings a three-game hitting streak into this matchup. During his last five outings he is hitting .300 with three doubles, a home run, two walks and four RBIs.

Marlins Player Leaders

• Kyle Stowers has a team-high OBP (.372), and paces the Marlins in hits (95). He's batting .295 and slugging.
• Including all the qualified players in MLB, his batting average ranks ninth, his on-base percentage ranks 19th, and he is sixth in slugging.
• Otto Lopez is hitting .252 with 11 doubles, 11 home runs and 33 walks. He's slugging .392 with an on-base percentage of .326.
• Including all qualified hitters, he ranks 99th in batting average, 79th in on-base percentage and 114th in slugging percentage.
• Xavier Edwards has accumulated a team-best .356 slugging percentage.
• Agustin Ramirez is batting .244 with 22 doubles, a triple, 14 home runs and 19 walks.

Padres vs Marlins Head to Head

• 7/22/2025: 4-3 MIA (Favorite: Marlins, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/21/2025: 2-1 SD (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/28/2025: 10-8 MIA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/27/2025: 8-6 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/26/2025: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/11/2024: 7-6 MIA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 8/10/2024: 9-8 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 8/9/2024: 6-2 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/29/2024: 9-1 MIA (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 5/28/2024: 4-0 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)

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