Padres vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 18

Odds updated as of 6:11 a.m.
On Monday in MLB, the San Diego Padres are up against the San Francisco Giants.
Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this game.
Padres vs Giants Game Info
- San Diego Padres (69-55) vs. San Francisco Giants (60-64)
- Date: Monday, August 18, 2025
- Time: 9:40 p.m. ET
- Venue: PETCO Park -- San Diego, California
- Coverage: SDPA and NBCS-BA
Padres vs Giants Odds & Moneyline
- All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: SD: (-142) | SF: (+120)
- Spread: SD: -1.5 (+155) | SF: +1.5 (-188)
- Total: 8 -- Over: (+106) | Under: (-130)
Padres vs Giants Probable Starting Pitchers
Probable Pitchers: Nestor Cortes (Padres) - 1-1, 5.71 ERA vs Robbie Ray (Giants) - 9-6, 2.98 ERA
The probable starters are Nestor Cortes (1-1) for the Padres and Robbie Ray (9-6) for the Giants. Cortes' team is 2-2-0 against the spread this season in his starts. Cortes' team is 2-0 this season when he starts and they're favored on the moneyline. The Giants have a 15-10-0 record against the spread in Ray's starts. The Giants have been the moneyline underdog in seven of Ray's starts this season, and they went 5-2 in those matchups.
Padres vs Giants Prediction & Pick
All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (57.1%)
Padres vs Giants Moneyline
- San Francisco is the underdog, +120 on the moneyline, while San Diego is a -142 favorite at home.
Padres vs Giants Spread
- The Giants are +1.5 on the spread (-188 to cover), and San Diego is +155 to cover the runline.
Padres vs Giants Over/Under
- Padres versus Giants, on Aug. 18, has an over/under of 8, with the over being +106 and the under -130.
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Padres vs Giants Betting Trends
- The Padres have come away with 39 wins in the 63 contests they have been listed as the favorites in this season.
- San Diego has a record of 24-15 when favored by -142 or more this year.
- The Padres and their opponents have gone over in 52 of their 122 games with a total set by sportsbooks this season.
- In 122 games with a line this season, the Padres have a mark of 68-54-0 against the spread.
- The Giants have a 21-24 record in games they were the underdog on the moneyline (winning 46.7% of those games).
- San Francisco has gone 9-9 when it has played as a moneyline underdog with odds of +120 or longer (50%).
- The Giants have played in 124 games with an over/under set, and have combined with opponents to go over the total 56 times (56-62-6).
- The Giants have collected a 53-71-0 record ATS this season.
Padres Player Leaders
- Manny Machado leads San Diego in total hits (139) this season while batting .291 with 50 extra-base hits. He has an on-base percentage of .353 and a slugging percentage of .479.
- Among the qualifying hitters in baseball, his batting average ranks 15th, his on-base percentage ranks 38th, and he is 33rd in slugging.
- Fernando Tatis Jr. leads San Diego in OBP (.370) this season, fueled by 123 hits. He's batting .266 while slugging .435.
- He is 56th in batting average, 14th in on-base percentage and 77th in slugging among qualifying batters.
- Tatis brings a two-game streak with at least one hit into this one. During his last five outings he is hitting .333 with two doubles, five walks and four RBIs.
- Luis Arraez has hit six homers with a team-high .399 SLG this season.
- Arraez takes a two-game hitting streak into this game. During his last five outings he is batting .263 with three doubles, two walks and two RBIs.
- Xander Bogaerts is batting .264 with a .333 OBP and 43 RBI for San Diego this season.
Giants Player Leaders
- Rafael Devers has racked up a team-best OBP (.377), and leads the Giants in hits (120). He's batting .257 and slugging.
- Including all qualifying hitters in MLB, his batting average places him 87th, his on-base percentage ranks 10th, and he is 49th in slugging.
- Devers hopes to build on a six-game hitting streak in this matchup. During his last 10 outings he is hitting .270 with a double, three home runs, five walks and three RBIs.
- Jung Hoo Lee has 28 doubles, 10 triples, six home runs and 39 walks while batting .260. He's slugging .409 with an on-base percentage of .324.
- Including all qualified players, he is 75th in batting average, 92nd in on-base percentage and 99th in slugging percentage.
- Willy Adames has 18 doubles, two triples, 19 home runs and 57 walks while hitting .222.
- Heliot Ramos paces his team with a .402 slugging percentage.
Padres vs Giants Head to Head
- 8/13/2025: 11-1 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -146, Underdog Moneyline: +124)
- 8/12/2025: 5-1 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
- 8/11/2025: 4-1 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
- 6/5/2025: 3-2 SF (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -112, Underdog Moneyline: -104)
- 6/4/2025: 6-5 SF (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
- 6/3/2025: 3-2 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
- 6/2/2025: 1-0 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
- 4/30/2025: 5-3 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
- 4/29/2025: 7-4 SD (Favorite: Giants, Spread: -1.5, Total: 6.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
- 9/15/2024: 4-3 SD (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
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