Diamondbacks vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 18

Odds updated as of 9:12 p.m.

The Arizona Diamondbacks versus the Cleveland Guardians is on the MLB schedule for Monday.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Diamondbacks vs Guardians Game Info

• Arizona Diamondbacks (60-65) vs. Cleveland Guardians (63-60)
• Date: Monday, August 18, 2025
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: ARID and CLEG

Diamondbacks vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-120) | CLE: (+102)
• Spread: ARI: +1.5 (-194) | CLE: -1.5 (+160)
• Total: 9 -- Over: (-104) | Under: (-118)

Diamondbacks vs Guardians Probable Starting Pitchers

Probable Pitchers: Zac Gallen (Diamondbacks) - 9-12, 5.31 ERA vs Gavin Williams (Guardians) - 7-4, 3.38 ERA

The probable pitchers are Zac Gallen (9-12) for the Diamondbacks and Gavin Williams (7-4) for the Guardians. Gallen's team is 11-14-0 against the spread this season in his starts. Gallen's team has won 42.9% of his starts when they are favored on the moneyline (6-8). The Guardians are 10-14-0 ATS in Williams' 24 starts that had a set spread. The Guardians have been the underdog on the moneyline in 14 of Williams' starts this season, and they went 5-9 in those games.

Diamondbacks vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (66.9%)

Diamondbacks vs Guardians Moneyline

• Looking at the moneyline for Diamondbacks-Guardians, Arizona is the favorite at -120, and Cleveland is +102 playing on the road.

Diamondbacks vs Guardians Spread

• The Guardians are 1.5-run favorites against the spread for this matchup with the Diamondbacks. The Guardians are +160 to cover, while the Diamondbacks are -194 to cover as a 1.5-run underdog on the runline.

Diamondbacks vs Guardians Over/Under

• The over/under for Diamondbacks-Guardians on Aug. 18 is 9. The over is -104, and the under is -118.

Bet on Arizona Diamondbacks vs. Cleveland Guardians on FanDuel today!

Diamondbacks vs Guardians Betting Trends

• The Diamondbacks have been victorious in 37, or 50.7%, of the 73 contests they have been chosen as favorites in this season.
• This season Arizona has come away with a win 26 times in 54 chances when named as a favorite of at least -120 on the moneyline.
• Contests with the Diamondbacks have gone over the total set by oddsmakers in 60 of 121 chances this season.
• In 121 games with a line this season, the Diamondbacks have a mark of 57-64-0 against the spread.
• The Guardians have won 43.1% of the games this season they were the underdog on the moneyline (28-37).
• In games it has played as a moneyline underdog with odds of +102 or longer, Cleveland has a 21-29 record (winning 42% of its games).
• The Guardians have played in 120 games with an over/under set, and have combined with their opponents to go over the total 55 times (55-61-4).
• The Guardians have a 62-58-0 record ATS this season.

Diamondbacks Player Leaders

• Geraldo Perdomo leads Arizona in slugging percentage (.437) thanks to 41 extra-base hits. He has a .286 batting average and an on-base percentage of .388.
• Among all qualifying batters in baseball, he ranks 22nd in batting average, seventh in on-base percentage, and 75th in slugging.
• Perdomo has hit safely in two games in a row. In his last five games he is batting .278 with a home run, six walks and an RBI.
• Corbin Carroll is hitting .251 with 22 doubles, 14 triples, 27 home runs and 43 walks. He's slugging .552 with an on-base percentage of .326.
• He ranks 100th in batting average, 88th in on-base percentage and seventh in slugging among qualified hitters.
• Carroll takes a five-game streak with at least one hit into this contest. During his last five outings he is batting .300 with a double, a home run, four walks and two RBIs.
• Ketel Marte leads Arizona with 102 hits and an OBP of .397 this season.
• Lourdes Gurriel Jr. is batting .246 with a .295 OBP and 66 RBI for Arizona this season.
• Gurriel brings a four-game hitting streak into this game. During his last five outings he is hitting .294 with a double, two home runs, two walks and seven RBIs.

Guardians Player Leaders

• Jose Ramirez has an on-base percentage of .364, a slugging percentage of .515, and has 132 hits, all club-highs for the Guardians (while batting .291).
• Including all qualified hitters in MLB, his batting average places him 14th, his on-base percentage ranks 21st, and he is 15th in slugging.
• Steven Kwan has 22 doubles, a triple, 10 home runs and 42 walks while hitting .281. He's slugging .396 with an on-base percentage of .340.
• His batting average is 27th among all qualified players, his on-base percentage ranks 57th, and he is 117th in slugging.
• Carlos Santana is batting .227 with nine doubles, 11 home runs and 52 walks.
• Kyle Manzardo is batting .238 with 14 doubles, two triples, 21 home runs and 40 walks.

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