Diamondbacks vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 18

Odds updated as of 6:11 a.m.

The Monday slate in MLB includes a matchup between the Arizona Diamondbacks and the Cleveland Guardians.

We've got you covered, in terms of the most important info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Diamondbacks vs Guardians Game Info

• Arizona Diamondbacks (60-65) vs. Cleveland Guardians (63-60)
• Date: Monday, August 18, 2025
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: ARID and CLEG

Diamondbacks vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-112) | CLE: (-104)
• Spread: ARI: +1.5 (-196) | CLE: -1.5 (+162)
• Total: 9 -- Over: (-104) | Under: (-118)

Diamondbacks vs Guardians Probable Starting Pitchers

Probable Pitchers: Zac Gallen (Diamondbacks) - 9-12, 5.31 ERA vs Gavin Williams (Guardians) - 7-4, 3.38 ERA

The Diamondbacks will give the ball to Zac Gallen (9-12, 5.31 ERA), who is eyeing win No. 10 on the season, and the Guardians will turn to Gavin Williams (7-4, 3.38 ERA). When Gallen starts, his team is 11-14-0 against the spread this season. Gallen's team is 6-8 this season when he starts and they are the moneyline favorite. The Guardians have a 10-14-0 ATS record in Williams' 24 starts with a set spread. The Guardians have been the moneyline underdog in 14 of Williams' starts this season, and they went 5-9 in those matchups.

Diamondbacks vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (66.5%)

Diamondbacks vs Guardians Moneyline

• Cleveland is the underdog, -104 on the moneyline, while Arizona is a -112 favorite at home.

Diamondbacks vs Guardians Spread

• The Guardians are 1.5-run favorites against the spread for this matchup with the Diamondbacks. The Guardians are +162 to cover, while the Diamondbacks are -196 to cover as a 1.5-run underdog on the runline.

Diamondbacks vs Guardians Over/Under

• The over/under for the Diamondbacks versus Guardians contest on Aug. 18 has been set at 9, with -104 odds on the over and -118 odds on the under.

Bet on Arizona Diamondbacks vs. Cleveland Guardians on FanDuel today!

Diamondbacks vs Guardians Betting Trends

• The Diamondbacks have been victorious in 37, or 50.7%, of the 73 contests they have been chosen as favorites in this season.
• This season Arizona has come away with a win 35 times in 71 chances when named as a favorite of at least -112 on the moneyline.
• The Diamondbacks' games have gone over the total in 60 of their 121 opportunities.
• The Diamondbacks are 57-64-0 against the spread in their 121 games with a line set by sportsbooks this season.
• The Guardians have a 28-37 record in games they were listed as the moneyline underdog (winning 43.1% of those games).
• When playing as a moneyline underdog with odds of -104 or longer, Cleveland has a record of 26-34 (43.3%).
• The Guardians have had an over/under set by oddsmakers 120 times, and have combined with opponents to go over the total in 55 of those games (55-61-4).
• The Guardians have a 62-58-0 record ATS this season (covering 51.7% of the time).

Diamondbacks Player Leaders

• Geraldo Perdomo has an OPS of .825, fueled by an OBP of .388 and a team-best slugging percentage of .437 this season. He has a .286 batting average.
• Among all qualifying hitters in the majors, his batting average ranks 22nd, his on-base percentage ranks seventh, and he is 75th in slugging.
• Perdomo will look for his third straight game with a hit in this contest. In his last five games he is batting .278 with a home run, six walks and an RBI.
• Corbin Carroll has 22 doubles, 14 triples, 27 home runs and 43 walks. He's batting .251 and slugging .552 with an on-base percentage of .326.
• Among qualifying hitters, his batting average places him 100th, his on-base percentage 88th, and his slugging percentage seventh.
• Carroll has picked up a hit in five straight games. In his last five games he is batting .300 with a double, a home run, four walks and two RBIs.
• Ketel Marte leads his team in OBP (.397) and total hits (102) this season.
• Lourdes Gurriel Jr. has 16 home runs, 66 RBI and a batting average of .246 this season.
• Gurriel has safely hit in four games in a row. In his last five games he is hitting .294 with a double, two home runs, two walks and seven RBIs.

Guardians Player Leaders

• Jose Ramirez has accumulated 132 hits with a .364 on-base percentage and a .515 slugging percentage, all club-bests for the Guardians. He's batting .291.
• Including all qualifying players in the big leagues, he is 15th in batting average, 21st in on-base percentage and 15th in slugging percentage.
• Steven Kwan is hitting .281 with 22 doubles, a triple, 10 home runs and 42 walks. He's slugging .396 with an on-base percentage of .340.
• Including all qualified hitters, his batting average places him 27th, his on-base percentage ranks 59th, and he is 117th in slugging.
• Carlos Santana has nine doubles, 11 home runs and 52 walks while hitting .227.
• Kyle Manzardo is hitting .238 with 14 doubles, two triples, 21 home runs and 40 walks.

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