Orioles vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 8

Odds updated as of 9:12 p.m.

The MLB's Wednesday slate includes the Baltimore Orioles facing the Chicago White Sox.

We've got you covered, in terms of the vital information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Orioles vs White Sox Game Info

• Baltimore Orioles (5-6) vs. Chicago White Sox (4-7)
• Date: Wednesday, April 8, 2026
• Time: 2:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and MASN

Orioles vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BAL: (-162) | CHW: (+136)
• Spread: BAL: -1.5 (+106) | CHW: +1.5 (-128)
• Total: 7.5 -- Over: (-105) | Under: (-115)

Orioles vs White Sox Probable Starting Pitchers

Probable Pitchers: Kyle Bradish (Orioles) - 0-2, 6.23 ERA vs Sean Burke (White Sox) - 0-1, 3.60 ERA

The Orioles will look to Kyle Bradish (0-2) against the White Sox and Sean Burke (0-1). Bradish has a record of 0-2-0 ATS in two starts with a spread this season. Bradish's team is 0-2 this season when he starts and they're favored on the moneyline. Burke has started just one game with a set spread, which the White Sox failed to cover. The White Sox were the moneyline underdog for one Burke start this season -- they lost.

Orioles vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Orioles win (50.7%)

Orioles vs White Sox Moneyline

• Chicago is the underdog, +136 on the moneyline, while Baltimore is a -162 favorite despite being on the road.

Orioles vs White Sox Spread

• The Orioles are at the White Sox and are favored by 1.5 runs (+106 to cover) on the runline. Chicago is -128 to cover.

Orioles vs White Sox Over/Under

• The over/under for Orioles-White Sox on April 8 is 7.5. The over is -105, and the under is -115.

Bet on Baltimore Orioles vs. Chicago White Sox on FanDuel today!

Orioles vs White Sox Betting Trends

• The Orioles have won in five of the eight contests they have been named as odds-on favorites in this year.
• Baltimore has played as a favorite of -162 or more just one time this year and came away with a loss in that game.
• The Orioles and their opponents have gone over the total this season in five of their 11 opportunities.
• In 11 games with a line this season, the Orioles have a mark of 3-8-0 against the spread.
• The White Sox have won four of the 11 games they were the underdog on the moneyline this season (36.4%).
• Chicago has a 2-3 record (winning 40% of its games) when it has played as a moneyline underdog of +136 or longer.
• The White Sox have had an over/under set by oddsmakers 11 times, and have combined with opponents to go over the total in seven of those games (7-4-0).
• The White Sox have gone 5-6-0 ATS this season.

Orioles Player Leaders

• Gunnar Henderson leads Baltimore with 11 hits, batting .244 this season with six extra-base hits. He has an on-base percentage of .333 and a slugging percentage of .556.
• Among all qualified hitters, he ranks 88th in batting average, his on-base percentage ranks 83rd, and he is 31st in slugging.
• Henderson has picked up at least one hit in two straight games. During his last five outings he is batting .350 with a double, three home runs, three walks and five RBIs.
• Taylor Ward is slashing .333/.431/.476 this season and leads the Orioles with an OPS of .908.
• His batting average ranks 21st among qualified players, his on-base percentage 16th, and his slugging percentage 56th.
• Ward has picked up a hit in three games in a row. In his last five games he is batting .333 with four doubles, five walks and two RBIs.
• Adley Rutschman has collected seven base hits, an OBP of .414 and a slugging percentage of .458 this season.
• Tyler O'Neill has one home run, four RBI and a batting average of .222 this season.
• O'Neill enters this game on a three-game hitting streak. In his last five games he is hitting .250 with an RBI.

White Sox Player Leaders

• Miguel Vargas has three doubles, a triple, a home run and six walks while batting .222. He's slugging .444 with an on-base percentage of .341.
• Including all qualifying hitters in the big leagues, he ranks 112th in batting average, 80th in on-base percentage and 67th in slugging percentage.
• Munetaka Murakami paces his team with seven hits. He has a batting average of .200 while slugging .543 with an on-base percentage of .326.
• Including all qualifying hitters, he is 134th in batting average, 87th in on-base percentage and 39th in slugging percentage.
• Chase Meidroth has a .357 on-base percentage and a .432 slugging percentage, both team-best marks for the White Sox.
• Colson Montgomery is batting .211 with a double, two home runs and four walks.

Orioles vs White Sox Head to Head

• 4/7/2026: 4-2 BAL (Favorite: Orioles, Spread: -1.5, Total: 6.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 4/6/2026: 2-1 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/17/2025: 3-1 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 9/16/2025: 8-7 BAL (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/15/2025: 4-1 BAL (Favorite: Orioles, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/1/2025: 3-2 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 5/31/2025: 4-2 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/30/2025: 2-1 BAL (Favorite: Orioles, Spread: -1.5, Total: 9, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 9/4/2024: 8-1 CHW (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -375, Underdog Moneyline: +300)
• 9/3/2024: 9-0 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -320, Underdog Moneyline: +260)

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