Notre Dame vs Boston College Prediction, Odds, Picks, Best Bets for Week 10 2025

The Notre Dame Fighting Irish are among the college football teams busy on Saturday, up against the Boston College Eagles.

We've got you covered, in terms of the most important information regarding NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Notre Dame vs Boston College Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Notre Dame: (-10000) | Boston College: (+2500)
• Spread: Notre Dame: -31.5 (-105) | Boston College: +31.5 (-115)
• Total: 55.5 -- Over: (-110) | Under: (-110)

Notre Dame vs Boston College Betting Trends

• Notre Dame's record against the spread is 3-4-0.
• There have been four Notre Dame games (of seven) that went over the total this year.
• Boston College has three wins in eight contests against the spread this year.
• Boston College has seen six of its eight games hit the over.

Notre Dame vs Boston College Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Fighting Irish win (96.4%)

Notre Dame vs Boston College Point Spread

Notre Dame is favored by 31.5 points (-105 to cover) in this matchup. Boston College, the underdog, is -115.

Notre Dame vs Boston College Over/Under

The over/under for the Notre Dame versus Boston College matchup on Nov. 1 has been set at 55.5, with -110 odds on the over and -110 odds on the under.

Notre Dame vs Boston College Moneyline

Boston College is the underdog, +2500 on the moneyline, while Notre Dame is a -10000 favorite.

Notre Dame vs. Boston College Points Insights

Notre Dame vs. Boston College Game Info

• Game day: Saturday, November 1, 2025
• Game time: 3:30 p.m. ET
• TV channel: ESPN
• Location: Boston, Massachusetts
• Stadium: Alumni Stadium (Chestnut Hill, MA)

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Check out even more in-depth Notre Dame vs. Boston College analysis on FanDuel Research.