Nebraska vs Iowa College Basketball Prediction, Odds, Picks, Best Bets for NCAA Tournament Sweet 16

A Sweet 16 matchup features the No. 4 seed Nebraska Cornhuskers (28-6, 15-5 Big Ten) squaring off against the No. 9 seed Iowa Hawkeyes (23-12, 10-10 Big Ten) on Thursday at Toyota Center. This NCAA Tournament matchup tips at 7:30 p.m. ET, with the winner moving on to the South regional final.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Nebraska vs. Iowa Game Info and Odds

• Game day: Thursday, March 26, 2026
• Game time: 7:30 p.m. ET
• TV channel: TBS
• Location: Houston, Texas
• Arena: Toyota Center

See these betting insights and trends before you bet on Thursday's Nebraska-Iowa spread (Nebraska -1.5) or total (131.5 points).

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Nebraska vs. Iowa: ATS Betting Stats and Trends

• Nebraska is 19-15-0 ATS this season.
• Iowa has covered 20 times in 35 chances against the spread this season.
• Nebraska (14-12) covers a higher percentage of games when it is favored by 1.5 points or more this season (53.8%) than Iowa (5-6) does as a 1.5+-point underdog (45.5%).
• Against the spread, the Cornhuskers have performed worse when playing at home, covering eight times in 18 home games, and seven times in 10 road games.
• This year, the Hawkeyes are 10-7-0 at home against the spread (.588 winning percentage). Away, they are 5-6-0 ATS (.455).
• Nebraska has beaten the spread 12 times in 21 conference games.
• Iowa is 9-13-0 against the spread in Big Ten play this season.

Nebraska vs. Iowa: Moneyline Betting Stats

• Nebraska has been chosen as the moneyline favorite in 23 games this year and has walked away with the win 21 times (91.3%) in those games.
• The Cornhuskers have been a -125 moneyline favorite on 20 occasions this season and won every game.
• Iowa has compiled a 2-9 record in games it was the underdog on the moneyline (winning 18.2% of those games).
• The Hawkeyes have a 2-7 record (winning only 22.2% of their games) when they have played as a moneyline underdog of +104 or longer.
• The moneyline set for this matchup implies Nebraska has a 55.6% chance of walking away with the win.

Nebraska vs. Iowa Head-to-Head Comparison

• Nebraska is outscoring opponents by 11.3 points per game with a +385 scoring differential overall. It puts up 77.1 points per game (146th in college basketball) and gives up 65.8 per contest (15th in college basketball).
• Nebraska's leading scorer, Pryce Sandfort, ranks 97th in college basketball averaging 17.9 points per game.
• Iowa's +312 scoring differential (outscoring opponents by 8.9 points per game) is a result of putting up 74.9 points per game (203rd in college basketball) while allowing 66 per outing (17th in college basketball).
• Iowa's leading scorer, Bennett Stirtz, ranks 39th in the country, scoring 19.7 points per game.
• The Cornhuskers pull down 32.4 rebounds per game (144th in college basketball) compared to the 31.4 of their opponents.
• Rienk Mast averages 5.8 rebounds per game (ranking 327th in college basketball) to lead the Cornhuskers.
• The Hawkeyes average 27 rebounds per game (355th in college basketball), compared to the 26 of their opponents.
• Tavion Banks is 732nd in the nation with 4.7 rebounds per game, leading the Hawkeyes.
• Nebraska puts up 102.6 points per 100 possessions (65th in college basketball), while giving up 87.5 points per 100 possessions (28th in college basketball).
• The Hawkeyes rank 16th in college basketball averaging 107.4 points per 100 possessions on offense, and defensively are 160th, allowing 94.6 points per 100 possessions.

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