Diamondbacks vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for May 18

Odds updated as of 5:11 a.m.

The Arizona Diamondbacks will take on the San Francisco Giants in MLB action on Monday.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Diamondbacks vs Giants Game Info

• Arizona Diamondbacks (22-23) vs. San Francisco Giants (20-27)
• Date: Monday, May 18, 2026
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: Dbacks.TV and NBCS-BA

Diamondbacks vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-136) | SF: (+116)
• Spread: ARI: -1.5 (+146) | SF: +1.5 (-178)
• Total: 9 -- Over: (-110) | Under: (-110)

Diamondbacks vs Giants Probable Starting Pitchers

Probable Pitchers: Zac Gallen (Diamondbacks) - 1-4, 5.02 ERA vs Robbie Ray (Giants) - 3-5, 3.04 ERA

This contest's pitching matchup is set, as the Diamondbacks will send Zac Gallen (1-4) to the mound, while Robbie Ray (3-5) will answer the bell for the Giants. Gallen and his team have a record of 5-4-0 against the spread when he starts. Gallen's team has been victorious in 33.3% of the games he's started as the moneyline favorite with a record of 1-2. When Ray starts, the Giants have gone 4-5-0 against the spread. The Giants have a 2-4 record in Ray's six starts this season when they were the underdog on the moneyline.

Diamondbacks vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (55.7%)

Diamondbacks vs Giants Moneyline

• Looking at the moneyline for Giants-Diamondbacks, San Francisco is the underdog at +116, and Arizona is -136 playing at home.

Diamondbacks vs Giants Spread

• The Giants are +1.5 on the run line against the Diamondbacks. The Giants are -178 to cover, and the Diamondbacks are +146.

Diamondbacks vs Giants Over/Under

• An over/under of 9 has been set for Diamondbacks-Giants on May 18, with the over being -110 and the under -110.

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Diamondbacks vs Giants Betting Trends

• The Diamondbacks have won in nine, or 60%, of the 15 contests they have been named as odds-on favorites in this year.
• This year Arizona has won three of six games when listed as at least -136 on the moneyline.
• The Diamondbacks and their opponents have gone over the total this season in 22 of their 44 opportunities.
• The Diamondbacks have an against the spread mark of 26-18-0 in 44 games with a line this season.
• The Giants have gone 13-20 in games they were listed as the moneyline underdog (winning 39.4% of those games).
• San Francisco has a record of 7-7 when it has played as a moneyline underdog with odds of +116 or longer (50%).
• In the 47 games oddsmakers have set an over/under for the Giants, they have combined with opponents to go over the total 20 times (20-24-3).
• The Giants have collected a 20-27-0 record against the spread this season.

Diamondbacks Player Leaders

• Ildemaro Vargas leads Arizona in slugging percentage (.549) and total hits (51) this season. He's batting .333 with an on-base percentage of .354.
• Among all qualified batters, he is third in batting average, his on-base percentage ranks 53rd, and he is 13th in slugging.
• Corbin Carroll leads Arizona in OBP (.390) this season, fueled by 42 hits. He's batting .278 while slugging .543.
• He is 39th in batting average, 14th in on-base percentage and 14th in slugging in the majors.
• Carroll enters this game looking to extend his six-game hit streak. During his last 10 outings he is batting .353 with four doubles, three home runs, nine walks and five RBIs.
• Nolan Arenado is batting .273 with a .448 slugging percentage and 21 RBI this year.
• Geraldo Perdomo is batting .226 with a .343 OBP and 12 RBI for Arizona this season.
• Perdomo takes a three-game hitting streak into this game. In his last five games he is batting .211 with a double and four walks.

Giants Player Leaders

• Luis Arraez has accumulated a team-high OBP (.370) and slugging percentage (.437). He's batting .328.
• Including all qualified hitters in MLB, he is fifth in batting average, 35th in on-base percentage and 63rd in slugging percentage.
• Arraez hopes to build on a three-game hitting streak in this matchup. During his last five outings he is hitting .526 with two doubles, two home runs, four walks and two RBIs.
• Casey Schmitt's 43 hits pace his team. He has a batting average of .297 while slugging .531 with an on-base percentage of .344.
• Including all qualifying hitters, he ranks 22nd in batting average, 67th in on-base percentage and 19th in slugging percentage.
• Jung Hoo Lee has 10 doubles, a triple, three home runs and 10 walks while batting .266.
• Rafael Devers is hitting .246 with 10 doubles, five home runs and 13 walks.

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