Friday’s MLB Odds, Betting Lines and Predictions - Sept. 26

Friday's MLB slate features the Los Angeles Dodgers playing the Seattle Mariners at T-Mobile Park. We have predictions for every game on the schedule, so check them out below.
Today's MLB Odds and Predictions
St. Louis Cardinals at Chicago Cubs
Game Info
- When: 2:20 p.m. ET
- Where: Wrigley Field
- TV Channel: MLB Network, MARQ and FDSMW
- Probable Pitchers: vs. Miles Mikolas
- Records: Cubs (89-70), Cardinals (78-81)
numberFire Prediction
- numberFire Predicted Favorite: Cubs
- Cubs Win Probability: 61.54%
- Cardinals Win Probability: 38.46%
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Chicago White Sox at Washington Nationals Odds, Lines & Predictions
Game Info
- When: 6:45 p.m. ET
- Where: Nationals Park
- TV Channel: MASN2 and CHSN
- Probable Pitchers: Cade Cavalli vs. Yoendrys Gomez
- Records: Nationals (65-94), White Sox (58-101)
- Nationals Moneyline Odds: -130
- White Sox Moneyline Odds: +110
numberFire Prediction
- numberFire Predicted Favorite: Nationals
- Nationals Win Probability: 55.80%
- White Sox Win Probability: 44.20%
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Minnesota Twins at Philadelphia Phillies Odds, Lines & Predictions
Game Info
- When: 6:45 p.m. ET
- Where: Citizens Bank Park
- TV Channel: NBCS-PH and MNNT
- Probable Pitchers: Aaron Nola vs. Joe Ryan
- Records: Phillies (94-65), Twins (69-90)
- Phillies Moneyline Odds: -166
- Twins Moneyline Odds: +140
numberFire Prediction
- numberFire Predicted Favorite: Phillies
- Phillies Win Probability: 51.04%
- Twins Win Probability: 48.96%
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Baltimore Orioles at New York Yankees Odds, Lines & Predictions
Game Info
- When: 7:05 p.m. ET
- Where: Yankee Stadium
- TV Channel: MLB Network, YES and MASN
- Probable Pitchers: Will Warren vs. Trevor Rogers
- Records: Yankees (91-68), Orioles (75-84)
- Yankees Moneyline Odds: -152
- Orioles Moneyline Odds: +128
numberFire Prediction
- numberFire Predicted Favorite: Yankees
- Yankees Win Probability: 52.75%
- Orioles Win Probability: 47.25%
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Tampa Bay Rays at Toronto Blue Jays Odds, Lines & Predictions
Game Info
- When: 7:07 p.m. ET
- Where: Rogers Centre
- TV Channel: Apple TV+
- Probable Pitchers: Shane Bieber vs. Adrian Houser
- Records: Blue Jays (91-68), Rays (77-82)
- Blue Jays Moneyline Odds: -180
- Rays Moneyline Odds: +152
numberFire Prediction
- numberFire Predicted Favorite: Blue Jays
- Blue Jays Win Probability: 51.54%
- Rays Win Probability: 48.46%
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New York Mets at Miami Marlins Odds, Lines & Predictions
Game Info
- When: 7:10 p.m. ET
- Where: loanDepot park
- TV Channel: FDSFL and WPIX
- Probable Pitchers: Sandy Alcantara vs. Brandon Sproat
- Records: Marlins (77-82), Mets (82-77)
- Mets Moneyline Odds: -134
- Marlins Moneyline Odds: +114
numberFire Prediction
- numberFire Predicted Favorite: Marlins
- Marlins Win Probability: 50.33%
- Mets Win Probability: 49.67%
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Texas Rangers at Cleveland Guardians Odds, Lines & Predictions
Game Info
- When: 7:10 p.m. ET
- Where: Progressive Field
- TV Channel: MLB Network, CLEG and Victory+
- Probable Pitchers: Slade Cecconi vs. Jack Leiter
- Records: Guardians (86-73), Rangers (80-79)
- Guardians Moneyline Odds: -148
- Rangers Moneyline Odds: +126
numberFire Prediction
- numberFire Predicted Favorite: Rangers
- Rangers Win Probability: 51.23%
- Guardians Win Probability: 48.77%
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Detroit Tigers at Boston Red Sox Odds, Lines & Predictions
Game Info
- When: 7:10 p.m. ET
- Where: Fenway Park
- TV Channel: Apple TV+
- Probable Pitchers: Kyle Harrison vs. Casey Mize
- Records: Red Sox (87-72), Tigers (86-73)
- Red Sox Moneyline Odds: -122
- Tigers Moneyline Odds: +104
numberFire Prediction
- numberFire Predicted Favorite: Red Sox
- Red Sox Win Probability: 50.05%
- Tigers Win Probability: 49.95%
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Pittsburgh Pirates at Atlanta Braves Odds, Lines & Predictions
Game Info
- When: 7:15 p.m. ET
- Where: Truist Park
- TV Channel: FDSSO and SportsNet PT
- Probable Pitchers: Joey Wentz vs. Mitch Keller
- Records: Braves (75-84), Pirates (69-90)
- Braves Moneyline Odds: -156
- Pirates Moneyline Odds: +132
numberFire Prediction
- numberFire Predicted Favorite: Braves
- Braves Win Probability: 56.27%
- Pirates Win Probability: 43.73%
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Cincinnati Reds at Milwaukee Brewers Odds, Lines & Predictions
Game Info
- When: 8:10 p.m. ET
- Where: American Family Field
- TV Channel: FDSWI and FDSOH
- Probable Pitchers: Quinn Priester vs. Zack Littell
- Records: Brewers (96-63), Reds (81-78)
- Brewers Moneyline Odds: -164
- Reds Moneyline Odds: +138
numberFire Prediction
- numberFire Predicted Favorite: Brewers
- Brewers Win Probability: 60.20%
- Reds Win Probability: 39.80%
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Houston Astros at Los Angeles Angels Odds, Lines & Predictions
Game Info
- When: 9:38 p.m. ET
- Where: Angel Stadium
- TV Channel: FDSW and SCHN
- Probable Pitchers: Kyle Hendricks vs. Jason Alexander
- Records: Angels (71-87), Astros (85-74)
- Astros Moneyline Odds: -154
- Angels Moneyline Odds: +130
numberFire Prediction
- numberFire Predicted Favorite: Astros
- Astros Win Probability: 55.21%
- Angels Win Probability: 44.79%
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Arizona Diamondbacks at San Diego Padres Odds, Lines & Predictions
Game Info
- When: 9:40 p.m. ET
- Where: PETCO Park
- TV Channel: SDPA and ARID
- Probable Pitchers: Yu Darvish vs. Zac Gallen
- Records: Padres (87-72), Diamondbacks (80-79)
- Padres Moneyline Odds: -144
- Diamondbacks Moneyline Odds: +122
numberFire Prediction
- numberFire Predicted Favorite: Padres
- Padres Win Probability: 55.96%
- Diamondbacks Win Probability: 44.04%
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Los Angeles Dodgers at Seattle Mariners
Game Info
- When: 9:40 p.m. ET
- Where: T-Mobile Park
- TV Channel: ROOT Sports NW and SportsNet LA
- Probable Pitchers: George Kirby vs. Emmet Sheehan
- Records: Mariners (89-69), Dodgers (90-69)
numberFire Prediction
- numberFire Predicted Favorite: Mariners
- Mariners Win Probability: 59.33%
- Dodgers Win Probability: 40.67%
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Kansas City Royals at Athletics
Game Info
- When: 10:05 p.m. ET
- Where: Sutter Health Park
- TV Channel: NBCS-CA and FDSKC
- Probable Pitchers: Luis Morales vs. Noah Cameron
- Records: Athletics (75-84), Royals (79-79)
numberFire Prediction
- numberFire Predicted Favorite: Athletics
- Athletics Win Probability: 53.91%
- Royals Win Probability: 46.09%
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Colorado Rockies at San Francisco Giants Odds, Lines & Predictions
Game Info
- When: 10:15 p.m. ET
- Where: Oracle Park
- TV Channel: NBCS-BA and COLR
- Probable Pitchers: Trevor McDonald vs. German Marquez
- Records: Giants (78-81), Rockies (43-115)
- Giants Moneyline Odds: -230
- Rockies Moneyline Odds: +190
numberFire Prediction
- numberFire Predicted Favorite: Giants
- Giants Win Probability: 62.51%
- Rockies Win Probability: 37.49%
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All MLB win probability predictions and picks are according to numberFire.