Mets vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 21

Odds updated as of 2:12 a.m.

MLB action on Thursday includes the New York Mets playing the Washington Nationals.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this matchup.

Mets vs Nationals Game Info

• New York Mets (67-59) vs. Washington Nationals (51-75)
• Date: Thursday, August 21, 2025
• Time: 4:05 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: MASN and SNY

Mets vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYM: (-142) | WSH: (+120)
• Spread: NYM: -1.5 (+120) | WSH: +1.5 (-144)
• Total: 8 -- Over: (-118) | Under: (-104)

Mets vs Nationals Probable Starting Pitchers

Probable Pitchers: Sean Manaea (Mets) - 1-1, 4.78 ERA vs MacKenzie Gore (Nationals) - 5-12, 4.04 ERA

The Mets will give the nod to Sean Manaea (1-1, 4.78 ERA), who is eyeing win No. 2 on the season, and the Nationals will turn to MacKenzie Gore (5-12, 4.04 ERA). Manaea and his team have a record of 1-5-0 against the spread when he starts. Manaea's team has won 20% of his starts when they are favored on the moneyline (1-4). The Nationals are 13-12-0 against the spread when Gore starts. The Nationals are 6-9 in Gore's 15 starts this season that they were the underdog on the moneyline.

Mets vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mets win (53.3%)

Mets vs Nationals Moneyline

• The Mets vs Nationals moneyline has New York as a -142 favorite, while Washington is a +120 underdog at home.

Mets vs Nationals Spread

• The Nationals are +1.5 on the run line against the Mets. The Nationals are -144 to cover, and the Mets are +120.

Mets vs Nationals Over/Under

• A total of 8 runs has been set for the Mets-Nationals game on Aug. 21, with the over available at -118 and the under at -104.

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Mets vs Nationals Betting Trends

• The Mets have come away with 51 wins in the 84 contests they have been listed as the favorites in this season.
• This season New York has been victorious 30 times in 55 chances when named as a favorite of at least -142 on the moneyline.
• Contests with the Mets have gone over the total set by sportsbooks in 52 of 119 chances this season.
• The Mets have an against the spread record of 56-63-0 in 119 games with a line this season.
• The Nationals have won 45 of the 101 games they were the moneyline underdog this season (44.6%).
• Washington has a 28-42 record (winning 40% of its games) when playing as a moneyline underdog of +120 or longer.
• The Nationals have played in 120 games with a set over/under, and have combined with opponents to go over the total 65 times (65-49-6).
• The Nationals have a 60-60-0 record against the spread this season (covering 50% of the time).

Mets Player Leaders

• Juan Soto has 110 hits this season and a team-best OBP of .385. He has a .249 batting average and a slugging percentage of .497.
• Among qualifying hitters in baseball, he ranks 101st in batting average, eighth in on-base percentage, and 23rd in slugging.
• Pete Alonso has 126 hits, which is tops among New York batters this season. He's batting .265 with 61 extra-base hits. He's also slugging .514 with an on-base percentage of .348.
• Among qualifiers, he is 57th in batting average, 44th in on-base percentage and 15th in slugging percentage.
• Francisco Lindor has an OPS of .780, fueled by an OBP of .327 and a team-best slugging percentage of .453 this season.
• Lindor has recorded a hit in eight games in a row. In his last 10 outings he is hitting .381 with four doubles, three home runs, four walks and seven RBIs.
• Brandon Nimmo has 20 home runs, 68 RBI and a batting average of .254 this season.

Nationals Player Leaders

• C.J. Abrams has a .457 slugging percentage, which paces the Nationals. He's batting .267 with an on-base percentage of .329.
• Including all qualifying players in the big leagues, he is 51st in batting average, 78th in on-base percentage and 56th in slugging percentage.
• James Wood has 120 hits with a .354 on-base percentage while slugging .474. Those stats all pace his team. He also has a batting average of .256.
• Including all qualified players, he ranks 89th in batting average, 36th in on-base percentage and 38th in slugging percentage.
• Luis Garcia is batting .260 with 24 doubles, a triple, nine home runs and 23 walks.
• Josh Bell is hitting .229 with 12 doubles, a triple, 16 home runs and 48 walks.

Mets vs Nationals Head to Head

• 8/20/2025: 5-4 WSH (Favorite: Mets, Spread: -1.5, Total: 9, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/19/2025: 8-1 NYM (Favorite: Mets, Spread: -1.5, Total: 9, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 6/12/2025: 4-3 NYM (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 6/11/2025: 5-0 NYM (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -275, Underdog Moneyline: +225)
• 6/10/2025: 5-4 NYM (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 4/28/2025: 19-5 NYM (Favorite: Mets, Spread: -1.5, Total: 9.5, Favorite Moneyline: -176, Underdog Moneyline: +148)
• 4/27/2025: 8-7 WSH (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/25/2025: 5-4 WSH (Favorite: Mets, Spread: -1.5, Total: 9.5, Favorite Moneyline: -186, Underdog Moneyline: +156)
• 9/18/2024: 10-0 NYM (Favorite: Mets, Spread: -1.5, Total: 7, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/17/2024: 10-1 NYM (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)

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