Marlins vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 20

Odds updated as of 2:11 a.m.

The MLB's Wednesday slate includes the Miami Marlins taking on the St. Louis Cardinals.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Marlins vs Cardinals Game Info

• Miami Marlins (59-67) vs. St. Louis Cardinals (63-64)
• Date: Wednesday, August 20, 2025
• Time: 6:40 p.m. ET
• Venue: loanDepot park -- Miami, Florida
• Coverage: FDSFL and FDSMW

Marlins vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIA: (-118) | STL: (-100)
• Spread: MIA: +1.5 (-210) | STL: -1.5 (+172)
• Total: 8.5 -- Over: (-104) | Under: (-118)

Marlins vs Cardinals Probable Starting Pitchers

Probable Pitchers: Sandy Alcantara (Marlins) - 6-11, 6.31 ERA vs Andre Pallante (Cardinals) - 6-10, 5.04 ERA

This contest's pitching matchup is set, as the Marlins will send Sandy Alcantara (6-11) to the mound, while Andre Pallante (6-10) will take the ball for the Cardinals. Alcantara and his team are 11-13-0 ATS this season when he starts. Alcantara's team has won 20% of his starts when they are favored on the moneyline (1-4). The Cardinals have a 13-11-0 record against the spread in Pallante's starts. The Cardinals have been the moneyline underdog in 15 of Pallante's starts this season, and they went 6-9 in those matchups.

Marlins vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (50.6%)

Marlins vs Cardinals Moneyline

• The Marlins vs Cardinals moneyline has Miami as a -118 favorite, while St. Louis is a -100 underdog on the road.

Marlins vs Cardinals Spread

• The Cardinals are 1.5-run favorites against the spread for this matchup with the Marlins. The Cardinals are +172 to cover, while the Marlins are -210 to cover as a 1.5-run underdog on the runline.

Marlins vs Cardinals Over/Under

• A total of 8.5 runs has been set for the Marlins-Cardinals game on Aug. 20, with the over available at -104 and the under at -118.

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Marlins vs Cardinals Betting Trends

• The Marlins have been chosen as favorites in 19 games this year and have walked away with the win seven times (36.8%) in those games.
• This season Miami has been victorious four times in 14 chances when named as a favorite of at least -118 on the moneyline.
• The Marlins and their opponents have hit the over in 58 of their 122 games with a total set by oddsmakers this season.
• The Marlins have posted a record of 71-51-0 against the spread this season.
• The Cardinals have a 33-34 record in games they were listed as the moneyline underdog (winning 49.3% of those games).
• St. Louis is 22-29 (winning 43.1% of its games) when playing as a moneyline underdog of -100 or longer.
• In the 122 games bookmakers have set an over/under for the Cardinals, they have combined with opponents to go over the total 63 times (63-54-5).
• The Cardinals have a 63-59-0 record against the spread this season (covering 51.6% of the time).

Marlins Player Leaders

• Xavier Edwards has an OPS of .735, fueled by an OBP of .359 and a team-best slugging percentage of .376 this season. He has a .302 batting average.
• Among all qualified batters in baseball, he ranks seventh in batting average, 27th in on-base percentage, and 138th in slugging.
• Otto Lopez is hitting .240 with 17 doubles, 11 home runs and 39 walks. He's slugging .361 with an on-base percentage of .309.
• His batting average ranks 121st among qualified players, his on-base percentage 117th, and his slugging percentage 149th.
• Lopez has picked up a hit in two straight games. During his last five outings he is hitting .211 with a double, a walk and two RBIs.
• Agustin Ramirez has collected 96 base hits, an OBP of .289 and a slugging percentage of .443 this season.
• Ramirez heads into this game with two games in a row with at least one hit. During his last five outings he is batting .263 with two doubles, a home run and an RBI.
• Eric Wagaman has been key for Miami with 91 hits, an OBP of .283 plus a slugging percentage of .365.

Cardinals Player Leaders

• Alec Burleson has totaled 115 hits, a team-best for the Cardinals. He's batting .287 and slugging .454 with an on-base percentage of .339.
• Including all the qualifying hitters in MLB, his batting average is 23rd, his on-base percentage ranks 56th, and he is 60th in slugging.
• Burleson enters this game on a four-game hitting streak. During his last five outings he is batting .381 with a double, a triple, two walks and three RBIs.
• Willson Contreras has 29 doubles, 16 home runs and 39 walks while hitting .260. He's slugging .443 with an on-base percentage of .345.
• He ranks 73rd in batting average, 49th in on-base percentage and 71st in slugging percentage in MLB.
• Masyn Winn is hitting .260 with 26 doubles, nine home runs and 31 walks.
• Lars Nootbaar has 18 doubles, 13 home runs and 48 walks while hitting .238.

Marlins vs Cardinals Head to Head

• 8/19/2025: 7-4 STL (Favorite: Marlins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/18/2025: 8-3 STL (Favorite: Marlins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/30/2025: 2-0 MIA (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/29/2025: 5-0 MIA (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 7/28/2025: 7-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/19/2024: 4-3 MIA (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/18/2024: 9-8 MIA (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/17/2024: 7-6 STL (Favorite: Cardinals, Spread: -1.5, Total: 7, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 4/7/2024: 10-3 MIA (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/6/2024: 3-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)

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