Marlins vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 20

Odds updated as of 6:13 p.m.

In MLB action on Wednesday, the Miami Marlins play the St. Louis Cardinals.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Marlins vs Cardinals Game Info

• Miami Marlins (59-67) vs. St. Louis Cardinals (63-64)
• Date: Wednesday, August 20, 2025
• Time: 6:40 p.m. ET
• Venue: loanDepot park -- Miami, Florida
• Coverage: FDSFL and FDSMW

Marlins vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIA: (-120) | STL: (+102)
• Spread: MIA: +1.5 (-196) | STL: -1.5 (+162)
• Total: 8.5 -- Over: (-102) | Under: (-120)

Marlins vs Cardinals Probable Starting Pitchers

Probable Pitchers: Sandy Alcantara (Marlins) - 6-11, 6.31 ERA vs Andre Pallante (Cardinals) - 6-10, 5.04 ERA

The Marlins will look to Sandy Alcantara (6-11) against the Cardinals and Andre Pallante (6-10). Alcantara's team is 11-13-0 against the spread this season in his starts. Alcantara's team is 1-4 this season when he starts and they are the moneyline favorite. The Cardinals are 13-11-0 against the spread when Pallante starts. The Cardinals are 6-9 in Pallante's 15 starts this season that they were the underdog on the moneyline.

Marlins vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (51.3%)

Marlins vs Cardinals Moneyline

• Looking at the moneyline for Marlins-Cardinals, Miami is the favorite at -120, and St. Louis is +102 playing on the road.

Marlins vs Cardinals Spread

• The Cardinals are 1.5-run favorites against the spread for this matchup with the Marlins. The Cardinals are +162 to cover, while the Marlins are -196 to cover as a 1.5-run underdog on the runline.

Marlins vs Cardinals Over/Under

• An over/under of 8.5 has been set for Marlins-Cardinals on Aug. 20, with the over being -102 and the under -120.

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Marlins vs Cardinals Betting Trends

• The Marlins have come away with seven wins in the 19 contests they have been listed as the favorites in this season.
• Miami has a record of 4-10 in contests when sportsbooks favor them by -120 or more on the moneyline.
• The Marlins and their opponents have gone over in 58 of their 122 games with a total set by sportsbooks this season.
• The Marlins have an against the spread mark of 71-51-0 in 122 games with a line this season.
• The Cardinals have won 33 of the 67 games they were the underdog on the moneyline this season (49.3%).
• St. Louis is 20-27 (winning 42.6% of its games) when playing as a moneyline underdog of +102 or longer.
• The Cardinals have played in 122 games with a set over/under, and have combined with their opponents to go over the total 63 times (63-54-5).
• The Cardinals have put together a 63-59-0 record against the spread this season.

Marlins Player Leaders

• Xavier Edwards leads Miami in slugging percentage (.376) thanks to 25 extra-base hits. He has a .302 batting average and an on-base percentage of .359.
• Among qualifying hitters in MLB, his batting average ranks seventh, his on-base percentage ranks 27th, and he is 138th in slugging.
• Otto Lopez is hitting .240 with 17 doubles, 11 home runs and 39 walks. He's slugging .361 with an on-base percentage of .309.
• He ranks 120th in batting average, 117th in on-base percentage and 149th in slugging in MLB.
• Lopez has picked up at least one hit in two games in a row. In his last five games he is batting .211 with a double, a walk and two RBIs.
• Agustin Ramirez has 96 hits this season and has a slash line of .238/.289/.443.
• Ramirez has recorded a hit in two straight games. During his last five outings he is hitting .263 with two doubles, a home run and an RBI.
• Eric Wagaman is batting .234 with a .283 OBP and 41 RBI for Miami this season.

Cardinals Player Leaders

• Alec Burleson has racked up 115 hits, a team-high for the Cardinals. He's batting .287 and slugging .454 with an on-base percentage of .339.
• Including all the qualified hitters in the big leagues, he is 23rd in batting average, 57th in on-base percentage and 60th in slugging percentage.
• Burleson enters this game on a four-game hitting streak. During his last five outings he is hitting .381 with a double, a triple, two walks and three RBIs.
• Willson Contreras is batting .260 with 29 doubles, 16 home runs and 39 walks. He's slugging .443 with an on-base percentage of .345.
• His batting average is 73rd among all qualified players, his on-base percentage is 49th, and he is 70th in slugging.
• Masyn Winn is hitting .260 with 26 doubles, nine home runs and 31 walks.
• Lars Nootbaar is hitting .238 with 18 doubles, 13 home runs and 48 walks.

Marlins vs Cardinals Head to Head

• 8/19/2025: 7-4 STL (Favorite: Marlins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/18/2025: 8-3 STL (Favorite: Marlins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/30/2025: 2-0 MIA (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/29/2025: 5-0 MIA (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 7/28/2025: 7-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/19/2024: 4-3 MIA (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/18/2024: 9-8 MIA (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/17/2024: 7-6 STL (Favorite: Cardinals, Spread: -1.5, Total: 7, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 4/7/2024: 10-3 MIA (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/6/2024: 3-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)

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