Mariners vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for May 17

Odds updated as of 7:11 p.m.

On Sunday in MLB, the Seattle Mariners are up against the San Diego Padres.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Mariners vs Padres Game Info

• Seattle Mariners (22-25) vs. San Diego Padres (27-18)
• Date: Sunday, May 17, 2026
• Time: 7:20 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: Peacock

Mariners vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-146) | SD: (+124)
• Spread: SEA: -1.5 (+136) | SD: +1.5 (-164)
• Total: 7.5 -- Over: (-102) | Under: (-120)

Mariners vs Padres Probable Starting Pitchers

Probable Pitchers: George Kirby (Mariners) - 5-2, 2.84 ERA vs Lucas Giolito (Padres) - 0-0, 0.00 ERA

The Mariners will look to George Kirby (5-2) against the Padres and Lucas Giolito. Kirby and his team have a record of 5-4-0 against the spread when he starts. Kirby's team has a record of 6-3 this season when he starts and they are the favorite on the moneyline. Last season Giolito and his team were 17-9-0 against the spread in games he pitched. Giolito and his team finished with a 8-6 record in games he appeared in when they were moneyline underdogs a season ago.

Mariners vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (59.2%)

Mariners vs Padres Moneyline

• San Diego is the underdog, +124 on the moneyline, while Seattle is a -146 favorite at home.

Mariners vs Padres Spread

• The Padres are at +1.5 on the runline against the Mariners. The Padres are -164 to cover the spread, and the Mariners are +136.

Mariners vs Padres Over/Under

• Mariners versus Padres on May 17 has an over/under of 7.5 runs, with the odds on the over -102 and the under set at -120.

Bet on Seattle Mariners vs. San Diego Padres on FanDuel today!

Mariners vs Padres Betting Trends

• The Mariners have been victorious in 21, or 48.8%, of the 43 contests they have been chosen as favorites in this season.
• Seattle has a record of 10-7 when favored by -146 or more this year.
• The Mariners and their opponents have hit the over in 21 of their 47 games with a total set by oddsmakers this season.
• In 47 games with a line this season, the Mariners have a mark of 17-30-0 against the spread.
• The Padres have compiled a 10-8 record in games they were listed as the moneyline underdog (winning 55.6% of those games).
• San Diego has won all three games it has played as a moneyline underdog with odds of +124 or longer.
• The Padres have had an over/under set by bookmakers 45 times, and have combined with opponents to go over the total in 19 of those games (19-25-1).
• The Padres have a 25-20-0 record against the spread this season (covering 55.6% of the time).

Mariners Player Leaders

• Randy Arozarena leads Seattle in OBP (.394), slugging percentage (.453) and total hits (52) this season. He has a .306 batting average.
• Among qualified hitters in baseball, he is 12th in batting average, 13th in on-base percentage, and 53rd in slugging.
• Arozarena hopes to build on a two-game hitting streak in this matchup. In his last five games he is batting .474 with two doubles, a home run, three walks and four RBIs.
• J.P. Crawford is batting .217 with four doubles, six home runs and 29 walks, while slugging .377 with an on-base percentage of .361.
• He is 143rd in batting average, 44th in on-base percentage and 116th in slugging in the majors.
• Josh Naylor has 44 hits this season and has a slash line of .253/.318/.368.
• Naylor has recorded a hit in five games in a row. In his last five games he is batting .286 with a double and three walks.
• Julio Rodriguez has seven home runs, 20 RBI and a batting average of .255 this season.

Padres Player Leaders

• Xander Bogaerts has put up an on-base percentage of .333, a slugging percentage of .413, and has 42 hits, all club-highs for the Padres (while batting .263).
• Including all the qualifying hitters in MLB, he is 62nd in batting average, 86th in on-base percentage and 75th in slugging percentage.
• Gavin Sheets has nine doubles, seven home runs and 12 walks while batting .244. He's slugging .488 with an on-base percentage of .316.
• Manny Machado is hitting .182 with four doubles, six home runs and 22 walks.
• Jackson Merrill has eight doubles, four home runs and 15 walks while hitting .205.

Mariners vs Padres Head to Head

• 5/16/2026: 7-4 SD (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/15/2026: 2-0 SD (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/16/2026: 5-2 SD (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/15/2026: 7-6 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 4/14/2026: 4-1 SD (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/27/2025: 4-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/26/2025: 7-6 SD (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/25/2025: 9-6 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/18/2025: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/17/2025: 4-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -190, Underdog Moneyline: +160)

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