Mariners vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for May 15

Odds updated as of 9:11 p.m.

The Seattle Mariners will face the San Diego Padres in MLB action on Friday.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Mariners vs Padres Game Info

• Seattle Mariners (22-23) vs. San Diego Padres (25-18)
• Date: Friday, May 15, 2026
• Time: 9:40 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: Mariners.TV and Padres.TV

Mariners vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-134) | SD: (+114)
• Spread: SEA: -1.5 (+158) | SD: +1.5 (-192)
• Total: 7.5 -- Over: (+102) | Under: (-124)

Mariners vs Padres Probable Starting Pitchers

Probable Pitchers: Emerson Hancock (Mariners) - 3-1, 3.21 ERA vs Randy Vasquez (Padres) - 4-1, 3.05 ERA

The probable pitchers are Emerson Hancock (3-1) for the Mariners and Randy Vasquez (4-1) for the Padres. Hancock and his team have a record of 3-5-0 against the spread when he starts. When Hancock starts a game and his team is the favorite on the moneyline, they have a record of 4-3. When Vasquez starts, the Padres have gone 6-2-0 against the spread. The Padres were the moneyline underdog for one Vasquez start this season -- they won.

Mariners vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (54.3%)

Mariners vs Padres Moneyline

• San Diego is the underdog, +114 on the moneyline, while Seattle is a -134 favorite at home.

Mariners vs Padres Spread

• The Padres are +1.5 on the run line against the Mariners. The Padres are -192 to cover, and the Mariners are +158.

Mariners vs Padres Over/Under

• The over/under for the Mariners versus Padres contest on May 15 has been set at 7.5, with +102 odds on the over and -124 odds on the under.

Bet on Seattle Mariners vs. San Diego Padres on FanDuel today!

Mariners vs Padres Betting Trends

• The Mariners have been chosen as favorites in 41 games this year and have walked away with the win 21 times (51.2%) in those games.
• This season Seattle has come away with a win 18 times in 30 chances when named as a favorite of at least -134 on the moneyline.
• Contests with the Mariners have gone over the total set by sportsbooks in 20 of 45 chances this season.
• In 45 games with a line this season, the Mariners have a mark of 17-28-0 against the spread.
• The Padres have been the underdog on the moneyline 16 total times this season. They've gone 8-8 in those games.
• San Diego has gone 4-3 in games it has played as a moneyline underdog with odds of +114 or longer (57.1%).
• The Padres have had an over/under set by bookmakers 43 times, and have combined with opponents to go over the total in 18 of those games (18-24-1).
• The Padres have a 23-20-0 record ATS this season.

Mariners Player Leaders

• Randy Arozarena leads Seattle with 49 hits and an OBP of .389, plus a team-best slugging percentage of .454. He's batting .301.
• Among qualified batters in MLB, his batting average ranks 19th, his on-base percentage ranks 14th, and he is 53rd in slugging.
• Julio Rodriguez has nine doubles, seven home runs and 15 walks. He's batting .261 and slugging .428 with an on-base percentage of .325.
• He is 66th in batting average, 97th in on-base percentage and 62nd in slugging in the majors.
• J.P. Crawford is batting .215 with a .362 slugging percentage and 15 RBI this year.
• Crawford takes a three-game hitting streak into this game. During his last five outings he is hitting .286 with a double, a home run, two walks and four RBIs.
• Josh Naylor is batting .247 with a .311 OBP and 20 RBI for Seattle this season.
• Naylor has safely hit in three games in a row. During his last five outings he is hitting .250 with two doubles and three walks.

Padres Player Leaders

• Xander Bogaerts has 39 hits with a .331 on-base percentage and a .414 slugging percentage, all club-bests for the Padres. He's batting .257.
• Including all qualifying hitters in MLB, he ranks 77th in batting average, 85th in on-base percentage and 74th in slugging percentage.
• Manny Machado has four doubles, six home runs and 21 walks while hitting .190. He's slugging .340 with an on-base percentage of .287.
• His batting average is 159th among all qualified players, his on-base percentage ranks 140th, and he is 138th in slugging.
• Jackson Merrill has eight doubles, four home runs and 15 walks while batting .215.
• Gavin Sheets is hitting .229 with nine doubles, six home runs and nine walks.

Mariners vs Padres Head to Head

• 4/16/2026: 5-2 SD (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/15/2026: 7-6 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 4/14/2026: 4-1 SD (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/27/2025: 4-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/26/2025: 7-6 SD (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/25/2025: 9-6 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/18/2025: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/17/2025: 4-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 5/16/2025: 5-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/11/2024: 5-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)

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