Mariners vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for May 11

Odds updated as of 7:11 p.m.

Monday's slate in the MLB includes a matchup between the Seattle Mariners and the Houston Astros.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Mariners vs Astros Game Info

• Seattle Mariners (19-22) vs. Houston Astros (16-25)
• Date: Monday, May 11, 2026
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: Fox Sports 1, SCHN, and Mariners.TV

Mariners vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-148) | HOU: (+126)
• Spread: SEA: -1.5 (+114) | HOU: +1.5 (-137)
• Total: 8.5 -- Over: (-118) | Under: (-104)

Mariners vs Astros Probable Starting Pitchers

Probable Pitchers: George Kirby (Mariners) - 4-2, 2.94 ERA vs Peter Lambert (Astros) - 2-2, 2.42 ERA

The probable pitchers are George Kirby (4-2) for the Mariners and Peter Lambert (2-2) for the Astros. Kirby and his team have a record of 4-4-0 against the spread when he starts. Kirby's team has been victorious in 62.5% of the games he's started as the moneyline favorite with a record of 5-3. When Lambert starts, the Astros have gone 2-2-0 against the spread. The Astros have a 2-1 record in Lambert's three starts this season when they were the moneyline underdog.

Mariners vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (57.5%)

Mariners vs Astros Moneyline

• Looking at the moneyline for Astros-Mariners, Houston is the underdog at +126, and Seattle is -148 playing on the road.

Mariners vs Astros Spread

• The Astros are hosting the Mariners, and are +1.5 on the runline. The Astros are +114 to cover the spread, and the Mariners are -137.

Mariners vs Astros Over/Under

• The over/under for the Mariners versus Astros game on May 11 has been set at 8.5, with -118 odds on the over and -104 odds on the under.

Bet on Seattle Mariners vs. Houston Astros on FanDuel today!

Mariners vs Astros Betting Trends

• The Mariners have won in 18, or 48.6%, of the 37 contests they have been named as odds-on favorites in this year.
• This year Seattle has won seven of 13 games when listed as at least -148 on the moneyline.
• The Mariners' games have gone over the total in 18 of their 41 opportunities.
• The Mariners are 14-27-0 against the spread in their 41 games with a line set by sportsbooks this season.
• The Astros have put together a 10-14 record in games they were listed as the moneyline underdog (winning 41.7% of those games).
• When it has played as a moneyline underdog with odds of +126 or longer, Houston has a 3-9 record (winning only 25% of its games).
• The Astros have played in 41 games with a set over/under, and have combined with opponents to go over the total 26 times (26-14-1).
• The Astros have a 16-25-0 record ATS this season.

Mariners Player Leaders

• Julio Rodriguez has 44 hits to go with a slugging percentage of .432, both of which are tops among Seattle hitters this season. He has a .272 batting average and an on-base percentage of .337.
• Among qualifying batters in the majors, his batting average ranks 51st, his on-base percentage ranks 78th, and he is 60th in slugging.
• Rodriguez hopes to build on a four-game hitting streak in this matchup. In his last five games he is hitting .300 with a double, two home runs, a walk and two RBIs.
• Randy Arozarena leads Seattle with an OBP of .368 this season while batting .279 with 17 walks and 26 runs scored. He's slugging .415.
• Among qualifying hitters, his batting average places him 41st, his on-base percentage 41st, and his slugging percentage 76th.
• Arozarena has picked up a hit in four games in a row. During his last five outings he is hitting .316 with an RBI.
• Josh Naylor has 38 hits this season and has a slash line of .255/.317/.383.
• Naylor heads into this game with nine games in a row with at least one hit. During his last 10 games he is batting .350 with two doubles, a home run, two walks and five RBIs.
• J.P. Crawford has four home runs, 11 RBI and a batting average of .204 this season.

Astros Player Leaders

• Yordan Alvarez has accumulated 48 hits with a .422 on-base percentage and a .642 slugging percentage, all club-highs for the Astros. He's batting .318.
• Including all the qualified hitters in MLB, he ranks ninth in batting average, second in on-base percentage and fourth in slugging percentage.
• Christian Walker has nine doubles, nine home runs and 15 walks while batting .282. He's slugging .523 with an on-base percentage of .353.
• Including all qualified hitters, he ranks 39th in batting average, 55th in on-base percentage and 20th in slugging percentage.
• Jose Altuve has 10 doubles, three home runs and 17 walks while batting .243.
• Isaac Paredes is hitting .256 with seven doubles, three home runs and 14 walks.

Mariners vs Astros Head to Head

• 4/13/2026: 6-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 4/12/2026: 6-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 4/11/2026: 8-7 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 4/10/2026: 9-6 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/21/2025: 7-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 9/20/2025: 6-4 SEA (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/19/2025: 4-0 SEA (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 7/20/2025: 11-3 HOU (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/19/2025: 7-6 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/18/2025: 6-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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