Kentucky vs Nicholls State College Basketball Prediction, Odds, Picks, Best Bets for Nov. 4

The Kentucky Wildcats open their 2025-26 college basketball season on November 4, 2025, battling the Nicholls State Colonels at Rupp Arena.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Kentucky vs. Nicholls State Game Info and Odds

• Game day: Tuesday, November 4, 2025
• Game time: 7 p.m. ET
• TV channel: SEC Network+
• Location: Lexington, Kentucky
• Arena: Rupp Arena

Kentucky vs. Nicholls State Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Kentucky win (92.4%)

Kentucky is a 29.5-point favorite against Nicholls State on Tuesday and the total has been set at 152.5 points. Here are some betting insights and trends if you are planning on making a wager on the outing.

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Kentucky vs. Nicholls State: ATS Betting Stats and Trends

• Kentucky put together an 18-18-0 record against the spread last season.
• Nicholls State won 19 games against the spread last season, while failing to cover 11 times.
• As a 29.5-point underdog or more in 2024-25, Nicholls State was 1-0 against the spread compared to the 1-2 ATS record Kentucky posted as a 29.5-point favorite.
• Against the spread last season, the Wildcats played better at home, covering 10 times in 18 home games, and four times in 10 road games.
• Last year, the Colonels were 6-6-0 at home against the spread (.500 winning percentage). On the road, they were 12-4-0 ATS (.750).

Kentucky vs. Nicholls State Head-to-Head Comparison

• On offense, Kentucky was the seventh-best squad in the nation (84.4 points per game) last season. On defense, it was 315th (77.2 points allowed per game).
• Last season, Kentucky was 63rd in the country in rebounds (34.1 per game) and 239th in rebounds allowed (32.1).
• At 16.9 assists per game, Kentucky was 17th-best in the country last year.
• Kentucky committed 10.4 turnovers per game last season and forced 9.9 per game, ranking 108th and 312th, respectively, in the country.
• Nicholls State posted 74 points per game (167th-ranked in college basketball) last season, while surrendering 69.6 points per contest (91st-ranked).
• With 33.7 boards per game, Nicholls State ranked 72nd in the nation. It gave up 32.7 rebounds per contest, which ranked 277th in college basketball.
• Nicholls State delivered 11.3 dimes per game, which ranked them 330th in the nation.
• Nicholls State was 87th in the country with 10.2 turnovers per game last year. Meanwhile, it ranked 112th with 12 forced turnovers per contest.

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