Kansas State vs Iowa State Prediction, Odds, Picks, Best Bets for Week 1 2025

The Saturday slate in college football includes a matchup between the Kansas State Wildcats and the Iowa State Cyclones.

We've got you covered, in terms of the vital info about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Kansas State vs Iowa State Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Kansas State: (-162) | Iowa State: (+134)
• Spread: Kansas State: -3.5 (-102) | Iowa State: +3.5 (-120)
• Total: 49.5 -- Over: (-110) | Under: (-110)

Kansas State vs Iowa State Betting Trends

• Kansas State beat the spread four times in 13 games last year.
• Kansas State's ATS record as at least 3.5-point favorites was 3-8 last year.
• Last season, seven of Kansas State's 13 games hit the over.
• Iowa State posted a 8-5-0 record against the spread last year.
• Iowa State did not lose ATS (1-0) as underdogs of 3.5 points or more last year.
• In 13 Iowa State games last year, eight of them went over the total.

Kansas State vs Iowa State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Wildcats win (58.9%)

Kansas State vs Iowa State Point Spread

Kansas State is favored by 3.5 points against Iowa State. Kansas State is -102 to cover the spread, while Iowa State is -120.

Kansas State vs Iowa State Over/Under

A total of 49.5 points has been set for the Kansas State-Iowa State matchup on Aug. 23, with the over available at -110 and the under at -110.

Kansas State vs Iowa State Moneyline

The Kansas State vs Iowa State moneyline has Kansas State as a -162 favorite, while Iowa State is a +134 underdog.

Kansas State vs. Iowa State Points Insights

• The average implied total for the Wildcats last season was 31.5 points, 4.5 more points than their implied total of 27 points in Saturday's game.
• The 29.0-point average implied total last season for the Cyclones is 6.0 more points than the team's 23-point implied total in this matchup.

Kansas State vs. Iowa State Game Info

• Game day: Saturday, August 23, 2025
• Game time: 12 p.m. ET
• TV channel: ESPN
• Location: Dublin, Ireland
• Stadium: Aviva Stadium

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Check out even more in-depth Kansas State vs. Iowa State analysis on FanDuel Research.