Guardians vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 9

Odds updated as of 6:12 p.m.

The Cleveland Guardians are among the MLB teams busy on Saturday, versus the Chicago White Sox.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Guardians vs White Sox Game Info

• Cleveland Guardians (60-55) vs. Chicago White Sox (42-74)
• Date: Saturday, August 9, 2025
• Time: 7:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and CLEG

Guardians vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-132) | CHW: (+112)
• Spread: CLE: -1.5 (+128) | CHW: +1.5 (-154)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Guardians vs White Sox Probable Starting Pitchers

Probable Pitchers: Joey Cantillo (Guardians) - 2-2, 4.37 ERA vs Sean Burke (White Sox) - 4-8, 4.23 ERA

This contest's pitching matchup is set, as the Guardians will send Joey Cantillo (2-2) to the mound, while Sean Burke (4-8) will answer the bell for the White Sox. Cantillo and his team are 3-3-0 ATS this season when he starts. Cantillo's team has a record of 2-1 this season when he starts and they are the favorite on the moneyline. When Burke starts, the White Sox have gone 11-7-0 against the spread. The White Sox have been the moneyline underdog in 18 of Burke's starts this season, and they went 8-10 in those matchups.

Guardians vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (50.2%)

Guardians vs White Sox Moneyline

• Chicago is the underdog, +112 on the moneyline, while Cleveland is a -132 favorite despite being on the road.

Guardians vs White Sox Spread

• The White Sox are hosting the Guardians, and are +1.5 on the runline. The White Sox are +128 to cover the spread, and the Guardians are -154.

Guardians vs White Sox Over/Under

• A total of 8.5 runs has been set for the Guardians-White Sox contest on Aug. 9, with the over available at -110 and the under at -110.

Bet on Cleveland Guardians vs. Chicago White Sox on FanDuel today!

Guardians vs White Sox Betting Trends

• The Guardians have been victorious in 30, or 65.2%, of the 46 contests they have been chosen as favorites in this season.
• Cleveland has a record of 17-6 in contests when bookmakers favor them by -132 or more on the moneyline.
• The Guardians and their opponents have gone over in 51 of their 112 games with a total set by sportsbooks this season.
• The Guardians are 59-53-0 against the spread in their 112 games that had a posted line this season.
• The White Sox have been the moneyline underdog 108 total times this season. They've finished 38-70 in those games.
• Chicago is 36-63 (winning just 36.4% of its games) when playing as a moneyline underdog of +112 or longer.
• The White Sox have played in 111 games with a set over/under, and have combined with their opponents to go over the total 50 times (50-53-8).
• The White Sox have a 61-50-0 record against the spread this season.

Guardians Player Leaders

• Jose Ramirez leads Cleveland with 125 hits and an OBP of .371, plus a team-best slugging percentage of .520. He's batting .296.
• He ranks 13th in batting average, 17th in on-base percentage, and 13th in slugging among qualified hitters in baseball.
• Ramirez hopes to build on a two-game hitting streak in this matchup. During his last five outings he is hitting .200 with a double, a home run, three walks and two RBIs.
• Steven Kwan has 20 doubles, a triple, nine home runs and 40 walks. He's batting .281 and slugging .394 with an on-base percentage of .342.
• Among qualified hitters, his batting average places him 29th, his on-base percentage 55th, and his slugging percentage 114th.
• Carlos Santana has 86 hits this season and has a slash line of .230/.321/.342.
• Kyle Manzardo is batting .239 with a .317 OBP and 49 RBI for Cleveland this season.
• Manzardo brings a two-game hitting streak into this matchup. In his last five games he is batting .214 with a double, two walks and an RBI.

White Sox Player Leaders

• Andrew Benintendi is batting .226 with 13 doubles, two triples, 14 home runs and 29 walks. He's slugging .416 with an on-base percentage of .292.
• Luis Robert has a .307 OBP to lead his team. He has a batting average of .225 while slugging .366.
• Including all qualifying hitters, he is 149th in batting average, 118th in on-base percentage and 142nd in slugging percentage.
• Lenyn Sosa has 97 hits with a .438 slugging percentage, both team-best marks for the White Sox.
• Mike Tauchman is hitting .276 with 13 doubles, a triple, eight home runs and 31 walks.

Guardians vs White Sox Head to Head

• 8/8/2025: 9-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/13/2025: 6-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/12/2025: 6-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/11/2025: 5-4 CHW (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/11/2025: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/10/2025: 6-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 4/9/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/8/2025: 1-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 9/11/2024: 6-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/10/2024: 5-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -235, Underdog Moneyline: +194)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!