Guardians vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for July 13

Odds updated as of 5:12 a.m.

On Sunday in MLB, the Cleveland Guardians are up against the Chicago White Sox.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Guardians vs White Sox Game Info

• Cleveland Guardians (45-49) vs. Chicago White Sox (32-64)
• Date: Sunday, July 13, 2025
• Time: 2:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and CLEG

Guardians vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-136) | CHW: (+116)
• Spread: CLE: -1.5 (+122) | CHW: +1.5 (-146)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Guardians vs White Sox Probable Starting Pitchers

Probable Pitchers: Joey Cantillo (Guardians) - 1-0, 3.79 ERA vs Aaron Civale (White Sox) - 1-6, 5.17 ERA

The Guardians will give the ball to Joey Cantillo (1-0, 3.79 ERA), who is eyeing win No. 2 on the season, and the White Sox will counter with Aaron Civale (1-6, 5.17 ERA). Cantillo has a record of 2-0-0 ATS in two starts with a spread this season. Cantillo has yet to start a game this season when his team was the moneyline favorite. The White Sox have gone 3-7-0 ATS in Civale's 10 starts that had a set spread. The White Sox have been the moneyline underdog in eight of Civale's starts this season, and they went 1-7 in those games.

Guardians vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (52.8%)

Guardians vs White Sox Moneyline

• The Guardians vs White Sox moneyline has Cleveland as a -136 favorite, while Chicago is a +116 underdog at home.

Guardians vs White Sox Spread

• The White Sox are +1.5 on the spread (-146 to cover), and Cleveland is +122 to cover the runline.

Guardians vs White Sox Over/Under

• Guardians versus White Sox, on July 13, has an over/under of 8.5, with the over being -110 and the under -110.

Bet on Cleveland Guardians vs. Chicago White Sox on FanDuel today!

Guardians vs White Sox Betting Trends

• The Guardians have been chosen as favorites in 32 games this year and have walked away with the win 19 times (59.4%) in those games.
• Cleveland has a record of 7-4 when favored by -136 or more this year.
• The Guardians and their opponents have hit the over in 39 of their 92 games with a total set by oddsmakers this season.
• The Guardians are 47-45-0 against the spread in their 92 games with a line set by sportsbooks this season.
• The White Sox are 29-61 in games they were listed as the moneyline underdog (winning 32.2% of those games).
• Chicago has a 25-53 record (winning just 32.1% of its games) when playing as a moneyline underdog of +116 or longer.
• The White Sox have combined with opponents to hit the over on the total 39 times this season for a 39-49-5 record against the over/under.
• The White Sox have gone 49-44-0 against the spread this season.

Guardians Player Leaders

• Jose Ramirez has 102 hits and an OBP of .367, both of which lead Cleveland hitters this season. He has a .297 batting average and a slugging percentage of .510.
• Among all qualifying hitters in the majors, his batting average ranks ninth, his on-base percentage ranks 26th, and he is 17th in slugging.
• Ramirez will look for his third straight game with a hit in this contest. During his last five outings he is batting .278 with three home runs, five walks and six RBIs.
• Steven Kwan leads Cleveland in slugging percentage (.398) thanks to 27 extra-base hits. He's batting .287 with an on-base percentage of .344.
• He ranks 23rd in batting average, 58th in on-base percentage and 104th in slugging in MLB.
• Kwan heads into this matchup looking to extend his two-game hit streak. During his last five outings he is hitting .136 with a walk and two RBIs.
• Carlos Santana has collected 72 base hits, an OBP of .331 and a slugging percentage of .365 this season.
• Kyle Manzardo is batting .217 with a .294 OBP and 34 RBI for Cleveland this season.
• Manzardo has safely hit in two straight games. During his last five outings he is batting .167 with a home run, three walks and an RBI.

White Sox Player Leaders

• Miguel Vargas has racked up a team-high OBP (.298), and leads the White Sox in hits (73). He's batting .218 and slugging.
• Including all qualified hitters in the majors, he is 144th in batting average, 131st in on-base percentage and 120th in slugging percentage.
• Andrew Benintendi is hitting .224 with 10 doubles, two triples, 10 home runs and 21 walks. He's slugging .409 with an on-base percentage of .287.
• Lenyn Sosa has put up a slugging percentage of .424, a team-high for the White Sox.
• Chase Meidroth is hitting .244 with six doubles, two home runs and 32 walks.

Guardians vs White Sox Head to Head

• 7/12/2025: 6-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/11/2025: 5-4 CHW (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/11/2025: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/10/2025: 6-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 4/9/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/8/2025: 1-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 9/11/2024: 6-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/10/2024: 5-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/9/2024: 5-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 7/4/2024: 8-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -225, Underdog Moneyline: +188)

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