Guardians vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for July 11

Odds updated as of 5:11 p.m.

The Cleveland Guardians will take on the Chicago White Sox in MLB action on Friday.

We've got you covered, in terms of the vital information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Guardians vs White Sox Game Info

• Cleveland Guardians (43-48) vs. Chicago White Sox (31-62)
• Date: Friday, July 11, 2025
• Time: 8:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and CLEG

Guardians vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-130) | CHW: (+110)
• Spread: CLE: -1.5 (+125) | CHW: +1.5 (-150)
• Total: 8 -- Over: (-115) | Under: (-105)

Guardians vs White Sox Probable Starting Pitchers

Probable Pitchers: Gavin Williams (Guardians) - 5-4, 3.61 ERA vs Jonathan Cannon (White Sox) - 3-7, 4.50 ERA

The Guardians will give the nod to Gavin Williams (5-4, 3.61 ERA), who is eyeing win No. 6 on the season, and the White Sox will turn to Jonathan Cannon (3-7, 4.50 ERA). Williams and his team have a record of 8-10-0 against the spread when he starts. When Williams starts a game and his team is the favorite on the moneyline, they have a record of 4-2. The White Sox are 5-7-0 ATS in Cannon's 12 starts with a set spread. The White Sox are 3-9 in Cannon's 12 starts this season that they were the moneyline underdog.

Guardians vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (50.9%)

Guardians vs White Sox Moneyline

• Cleveland is a -130 favorite on the moneyline, while Chicago is a +110 underdog at home.

Guardians vs White Sox Spread

• The Guardians are at the White Sox and are favored by 1.5 runs on the spread. The Guardians are +125 to cover the runline, with the White Sox being -150.

Guardians vs White Sox Over/Under

• A combined run total of 8 has been set for Guardians-White Sox on July 11, with the over at -115 and the under at -105.

Bet on Cleveland Guardians vs. Chicago White Sox on FanDuel today!

Guardians vs White Sox Betting Trends

• The Guardians have won in 17, or 58.6%, of the 29 contests they have been named as odds-on favorites in this year.
• This season Cleveland has come away with a win 10 times in 14 chances when named as a favorite of at least -130 on the moneyline.
• The Guardians' games have gone over the total in 38 of their 89 opportunities.
• The Guardians are 45-44-0 against the spread in their 89 games that had a posted line this season.
• The White Sox have put together a 28-59 record in games they were listed as the moneyline underdog (winning 32.2% of those games).
• In games it has played as a moneyline underdog with odds of +110 or longer, Chicago has gone 28-55 (33.7%).
• The White Sox have played in 90 games with a set over/under, and have combined with opponents to go over the total 38 times (38-47-5).
• The White Sox have a 48-42-0 record against the spread this season (covering 53.3% of the time).

Guardians Player Leaders

• Jose Ramirez leads Cleveland with 100 hits and an OBP of .366 this season. He has a .301 batting average and a slugging percentage of .512.
• Among all qualifying hitters, he is 10th in batting average, his on-base percentage ranks 27th, and he is 16th in slugging.
• Ramirez hopes to build on a three-game hitting streak in this matchup. In his last five games he is hitting .333 with a double, three home runs, four walks and six RBIs.
• Steven Kwan leads Cleveland in slugging percentage (.408) thanks to 27 extra-base hits. He's batting .292 with an on-base percentage of .350.
• Among qualifying hitters, his batting average ranks him 16th, his on-base percentage 48th, and his slugging percentage 98th.
• Carlos Santana has collected 69 base hits, an OBP of .326 and a slugging percentage of .353 this season.
• Kyle Manzardo has 13 home runs, 33 RBI and a batting average of .217 this season.

White Sox Player Leaders

• Miguel Vargas has racked up 72 hits with a .301 on-base percentage, leading the White Sox in both statistics. He's batting .220 and slugging .388.
• Including all qualified hitters in the big leagues, he ranks 144th in batting average, 129th in on-base percentage and 113th in slugging percentage.
• Andrew Benintendi is batting .223 with 10 doubles, two triples, 10 home runs and 19 walks. He's slugging .415 with an on-base percentage of .282.
• Chase Meidroth is hitting .247 with six doubles, two home runs and 31 walks.
• Lenyn Sosa's .408 slugging percentage paces his team.

Guardians vs White Sox Head to Head

• 4/10/2025: 6-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 4/9/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/8/2025: 1-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 9/11/2024: 6-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/10/2024: 5-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/9/2024: 5-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 7/4/2024: 8-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 7/3/2024: 8-2 CHW (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 7/2/2024: 7-6 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 5/12/2024: 7-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -174, Underdog Moneyline: +146)

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