Guardians vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for July 10

Odds updated as of 2:12 p.m.

On Friday in MLB, the Cleveland Guardians are up against the Chicago White Sox.

All the information you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Guardians vs White Sox Game Info

• Cleveland Guardians (43-48) vs. Chicago White Sox (31-62)
• Date: Friday, July 11, 2025
• Time: 3:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and CLEG

Guardians vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-120) | CHW: (+102)
• Spread: CLE: -1.5 (+130) | CHW: +1.5 (-156)
• Total: 8.5 -- Over: (-108) | Under: (-112)

Guardians vs White Sox Probable Starting Pitchers

Probable Pitchers: Logan Allen (Guardians) - 5-7, 4.07 ERA vs Shane Smith (White Sox) - 3-7, 4.20 ERA

The Guardians will give the nod to Logan Allen (5-7, 4.07 ERA), who is eyeing win No. 6 on the season, and the White Sox will counter with Shane Smith (3-7, 4.20 ERA). When Allen starts, his team is 6-9-0 against the spread this season. Allen's team has won each of the three games he's started as the moneyline favorite. The White Sox have a 7-10-0 ATS record in Smith's 17 starts that had a set spread. The White Sox have a 4-11 record in Smith's 15 starts this season when they were the moneyline underdog.

Guardians vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (53.9%)

Guardians vs White Sox Moneyline

• The Guardians vs White Sox moneyline has Cleveland as a -120 favorite, while Chicago is a +102 underdog at home.

Guardians vs White Sox Spread

• The Guardians are at the White Sox and are favored by 1.5 runs (+130 to cover) on the runline. Chicago is -156 to cover.

Guardians vs White Sox Over/Under

• An over/under of 8.5 has been set for Guardians-White Sox on July 11, with the over being -108 and the under -112.

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Guardians vs White Sox Betting Trends

• The Guardians have won in 17, or 58.6%, of the 29 contests they have been named as odds-on favorites in this year.
• This season Cleveland has come away with a win 13 times in 21 chances when named as a favorite of at least -120 on the moneyline.
• The Guardians' games have gone over the total in 38 of their 89 opportunities.
• The Guardians have an against the spread record of 45-44-0 in 89 games with a line this season.
• The White Sox have gone 28-59 in games they were listed as the moneyline underdog (winning 32.2% of those games).
• Chicago is 28-57 (winning only 32.9% of its games) when playing as a moneyline underdog of +102 or longer.
• The White Sox have played in 90 games with a set over/under, and have combined with their opponents to go over the total 38 times (38-47-5).
• The White Sox have collected a 48-42-0 record against the spread this season (covering 53.3% of the time).

Guardians Player Leaders

• Jose Ramirez has 100 hits and an OBP of .366, both of which are tops among Cleveland hitters this season. He has a .301 batting average and a slugging percentage of .512.
• He ranks 10th in batting average, 27th in on-base percentage, and 16th in slugging among qualifying hitters in baseball.
• Ramirez has recorded at least one hit in three straight games. In his last five games he is batting .333 with a double, three home runs, four walks and six RBIs.
• Steven Kwan has hit six homers this season while driving in 29 runs. He's batting .292 this season and slugging .408 with an on-base percentage of .350.
• Among qualifying hitters, his batting average ranks him 16th, his on-base percentage 48th, and his slugging percentage 98th.
• Carlos Santana has collected 69 base hits, an OBP of .326 and a slugging percentage of .353 this season.
• Kyle Manzardo has been key for Cleveland with 55 hits, an OBP of .289 plus a slugging percentage of .429.

White Sox Player Leaders

• Miguel Vargas has racked up a team-best OBP (.301), while leading the White Sox in hits (72). He's batting .220 and slugging.
• Including all qualifying players in the majors, he is 144th in batting average, 129th in on-base percentage and 113th in slugging percentage.
• Andrew Benintendi has 10 doubles, two triples, 10 home runs and 19 walks while hitting .223. He's slugging .415 with an on-base percentage of .282.
• Chase Meidroth is batting .247 with six doubles, two home runs and 31 walks.
• Lenyn Sosa is slugging .408 to pace his team.

Guardians vs White Sox Head to Head

• 4/10/2025: 6-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 4/9/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/8/2025: 1-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 9/11/2024: 6-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/10/2024: 5-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/9/2024: 5-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 7/4/2024: 8-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 7/3/2024: 8-2 CHW (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 7/2/2024: 7-6 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 5/12/2024: 7-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -174, Underdog Moneyline: +146)

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