Guardians vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for May 9

Odds updated as of 5:11 p.m.

In MLB action on Saturday, the Cleveland Guardians take on the Minnesota Twins.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Guardians vs Twins Game Info

• Cleveland Guardians (21-19) vs. Minnesota Twins (16-23)
• Date: Saturday, May 9, 2026
• Time: 6:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and Twins.TV

Guardians vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-118) | MIN: (+100)
• Spread: CLE: +1.5 (-194) | MIN: -1.5 (+160)
• Total: 8 -- Over: (-105) | Under: (-115)

Guardians vs Twins Probable Starting Pitchers

Probable Pitchers: Tanner Bibee (Guardians) - 0-5, 4.58 ERA vs Joe Ryan (Twins) - 2-3, 3.72 ERA

This contest's pitching matchup is set, as the Guardians will send Tanner Bibee (0-5) to the mound, while Joe Ryan (2-3) will get the nod for the Twins. When Bibee starts, his team is 1-7-0 against the spread this season. Bibee and his team have lost each of the four games he's started as the moneyline favorite. The Twins have a 4-4-0 ATS record in Ryan's eight starts that had a set spread. The Twins have been the moneyline underdog in four of Ryan's starts this season, and they went 1-3 in those matchups.

Guardians vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (54.1%)

Guardians vs Twins Moneyline

• Cleveland is a -118 favorite on the moneyline, while Minnesota is a +100 underdog on the road.

Guardians vs Twins Spread

• The Twins are 1.5-run favorites against the spread for this matchup with the Guardians. The Twins are +160 to cover, while the Guardians are -194 to cover as a 1.5-run underdog on the runline.

Guardians vs Twins Over/Under

• The over/under for Guardians-Twins on May 9 is 8. The over is -105, and the under is -115.

Bet on Cleveland Guardians vs. Minnesota Twins on FanDuel today!

Guardians vs Twins Betting Trends

• The Guardians have won in nine, or 50%, of the 18 contests they have been named as odds-on favorites in this year.
• This season Cleveland has come away with a win eight times in 16 chances when named as a favorite of at least -118 on the moneyline.
• The Guardians and their opponents have gone over in 20 of their 39 games with a total set by sportsbooks this season.
• The Guardians are 21-18-0 against the spread in their 39 games that had a posted line this season.
• The Twins have compiled a 12-16 record in games they were the underdog on the moneyline (winning 42.9% of those games).
• Minnesota has a 12-14 record (winning 46.2% of its games) when playing as a moneyline underdog of +100 or longer.
• In the 39 games oddsmakers have set an over/under for the Twins, they have combined with opponents to go over the total 25 times (25-13-1).
• The Twins are 18-21-0 ATS this season.

Guardians Player Leaders

• Jose Ramirez is batting .219 with eight doubles, six home runs and 28 walks. He has an on-base percentage of .345 and a slugging percentage of .397.
• Among qualified hitters, he ranks 138th in batting average, his on-base percentage ranks 71st, and he is 92nd in slugging.
• Ramirez hopes to build on a two-game hitting streak in this matchup. In his last five games he is hitting .235 with four walks and an RBI.
• Chase DeLauter leads Cleveland with 38 hits and an OBP of .392, plus a team-best slugging percentage of .548. He's batting .306.
• Among all qualified hitters, he ranks 18th in batting average, 18th in on-base percentage and 15th in slugging percentage.
• DeLauter takes an 11-game streak with at least one hit into this matchup. In his last 10 games he is hitting .514 with five doubles, a home run, five walks and seven RBIs.
• Brayan Rocchio is batting .264 with a .368 slugging percentage and 19 RBI this year.
• Rocchio takes a two-game hitting streak into this game. In his last five games he is hitting .176 with two walks.
• Steven Kwan is batting .221 with a .321 OBP and nine RBI for Cleveland this season.
• Kwan enters this game on a two-game hitting streak. During his last five outings he is batting .158 with a double and three walks.

Twins Player Leaders

• Byron Buxton has racked up 39 hits with a .542 slugging percentage, both team-high numbers for the Twins. He's batting .255 and with an on-base percentage of .307.
• Including all the qualifying hitters in MLB, he is 81st in batting average, 125th in on-base percentage and 17th in slugging percentage.
• Ryan Jeffers has a .408 OBP to lead his team. He has a batting average of .300 while slugging .520.
• He is currently 25th in batting average, ninth in on-base percentage and 26th in slugging percentage among all qualified hitters.
• Brooks Lee has five doubles, five home runs and nine walks while hitting .278.
• Luke Keaschall has eight doubles, a home run and 16 walks while batting .236.

Guardians vs Twins Head to Head

• 5/8/2026: 6-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/21/2025: 6-2 MIN (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 9/20/2025: 8-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/20/2025: 6-0 CLE (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/19/2025: 6-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/3/2025: 5-4 MIN (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 8/2/2025: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/1/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/21/2025: 5-1 CLE (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/1/2025: 4-3 CLE (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!