Guardians vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for April 29

Odds updated as of 5:16 p.m.

The Cleveland Guardians are among the MLB squads busy on Tuesday, versus the Minnesota Twins.

All the info you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Guardians vs Twins Game Info

• Cleveland Guardians (15-13) vs. Minnesota Twins (13-16)
• Date: Tuesday, April 29, 2025
• Time: 6:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CLEG and MNNT

Guardians vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-130) | MIN: (+110)
• Spread: CLE: -1.5 (+150) | MIN: +1.5 (-182)
• Total: 8 -- Over: (-122) | Under: (-100)

Guardians vs Twins Probable Starting Pitchers

Probable Pitchers: Tanner Bibee (Guardians) - 2-2, 5.19 ERA vs Chris Paddack (Twins) - 0-3, 6.45 ERA

The Guardians will give the nod to Tanner Bibee (2-2) against the Twins and Chris Paddack (0-3). Bibee's team is 3-2-0 against the spread in his starts this season. Bibee's team has a record of 2-1 this season when he starts and they are the favorite on the moneyline. In all of Paddack's five starts that had a set spread, the Twins failed to cover. The Twins were the moneyline underdog for one Paddack start this season -- they lost.

Guardians vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (51.8%)

Guardians vs Twins Moneyline

• The Guardians vs Twins moneyline has Cleveland as a -130 favorite, while Minnesota is a +110 underdog on the road.

Guardians vs Twins Spread

• The Guardians are favored by 1.5 runs at home versus the Twins. The Guardians are +150 to cover the spread, while the Twins are -182.

Guardians vs Twins Over/Under

• Guardians versus Twins on April 29 has an over/under of 8 runs, with the odds on the over -122 and the under set at -100.

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Guardians vs Twins Betting Trends

• The Guardians have been victorious in eight, or 72.7%, of the 11 contests they have been chosen as favorites in this season.
• This season Cleveland has been victorious five times in six chances when named as a favorite of at least -130 on the moneyline.
• The Guardians and their opponents have gone over in 16 of their 28 games with a total set by sportsbooks this season.
• In 28 games with a line this season, the Guardians have a mark of 12-16-0 against the spread.
• The Twins have won 14.3% of the games this season they were the underdog on the moneyline (1-6).
• Minnesota has played as a moneyline underdog of +110 or longer in only two games this season, which it lost both.
• The Twins have had an over/under set by bookmakers 29 times, and have combined with opponents to go over the total in 11 of those games (11-15-3).
• The Twins have put together a 15-14-0 record ATS this season (covering 51.7% of the time).

Guardians Player Leaders

• Steven Kwan has an OPS of .895, fueled by an OBP of .395 to go with a slugging percentage of .500. He has a .345 batting average, as well.
• Among qualified hitters in the majors, he is sixth in batting average, 17th in on-base percentage, and 32nd in slugging.
• Kwan has hit safely in 11 straight games. In his last 10 outings he is batting .410 with four doubles, a home run, three walks and four RBI.
• Jose Ramirez is hitting .265 with four doubles, five home runs and nine walks, while slugging .459 with an on-base percentage of .321.
• Among qualifiers, he ranks 58th in batting average, 85th in on-base percentage and 48th in slugging percentage.
• Ramirez has picked up a hit in two games in a row. During his last five outings he is batting .278 with a walk and an RBI.
• Kyle Manzardo leads Cleveland in total hits (18) this season, and 11 of those have gone for extra bases.
• Manzardo has logged a hit or more in two games in a row. In his last five games he is batting .211 with a double, a home run, a walk and two RBI.
• Gabriel Arias has four home runs, 11 RBI and a batting average of .271 this season.
• Arias has safely hit in four straight games. In his last five games he is hitting .250 with three doubles and an RBI.

Twins Player Leaders

• Byron Buxton has totaled 25 hits with a .500 slugging percentage, both team-best numbers for the Twins. He's batting .245 and with an on-base percentage of .275.
• Including all the qualifying players in the majors, his batting average ranks 84th, his on-base percentage ranks 129th, and he is 32nd in slugging.
• Buxton enters this game on a three-game hitting streak. During his last five outings he is batting .300 with a triple, two home runs, a walk and seven RBI.
• Ty France has a .330 on-base percentage while slugging .366. Both are team-highs. He has a batting average of .248.
• He is currently 75th in batting average, 70th in on-base percentage and 109th in slugging percentage among all qualifying hitters.
• Trevor Larnach is batting .232 with two doubles, four home runs and 13 walks.
• Ryan Jeffers is batting .257 with seven doubles, a home run and nine walks.

Guardians vs Twins Head to Head

• 4/28/2025: 11-1 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/19/2024: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/18/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/17/2024: 4-1 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/16/2024: 4-3 CLE (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/11/2024: 5-3 CLE (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/9/2024: 6-3 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/9/2024: 4-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/19/2024: 5-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/18/2024: 11-4 CLE (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)

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