Guardians vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for July 28

Odds updated as of 6:12 p.m.

Monday's slate in the MLB includes a matchup between the Cleveland Guardians and the Colorado Rockies.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Guardians vs Rockies Game Info

• Cleveland Guardians (52-53) vs. Colorado Rockies (27-78)
• Date: Monday, July 28, 2025
• Time: 6:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CLEG and COLR

Guardians vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-270) | COL: (+220)
• Spread: CLE: -1.5 (-132) | COL: +1.5 (+110)
• Total: 9 -- Over: (-102) | Under: (-120)

Guardians vs Rockies Probable Starting Pitchers

Probable Pitchers: Slade Cecconi (Guardians) - 5-4, 3.76 ERA vs Bradley Blalock (Rockies) - 1-2, 8.67 ERA

The probable pitchers are Slade Cecconi (5-4) for the Guardians and Bradley Blalock (1-2) for the Rockies. Cecconi and his team are 8-4-0 ATS this season when he starts. Cecconi's team has won 66.7% of his starts when they are favored on the moneyline (4-2). The Rockies have a 2-3-0 record against the spread in Blalock's starts. The Rockies are 1-4 in Blalock's five starts this season that they were the moneyline underdog.

Guardians vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (62.7%)

Guardians vs Rockies Moneyline

• Colorado is a +220 underdog on the moneyline, while Cleveland is a -270 favorite at home.

Guardians vs Rockies Spread

• The Rockies are +1.5 on the run line against the Guardians. The Rockies are +110 to cover, and the Guardians are -132.

Guardians vs Rockies Over/Under

• A combined run total of 9 has been set for Guardians-Rockies on July 28, with the over at -102 and the under at -120.

Bet on Cleveland Guardians vs. Colorado Rockies on FanDuel today!

Guardians vs Rockies Betting Trends

• The Guardians have won in 25, or 62.5%, of the 40 contests they have been named as odds-on favorites in this year.
• These are the best odds of a victory sportsbooks have given Cleveland this season, with a -270 moneyline set for this game.
• The Guardians and their opponents have gone over the total this season in 46 of their 103 opportunities.
• The Guardians are 53-50-0 against the spread in their 103 games with a line set by sportsbooks this season.
• The Rockies have won 25 of the 99 games they were listed as the moneyline underdog this season (25.3%).
• Colorado is 5-31 (winning only 13.9% of its games) when it has played as a moneyline underdog of +220 or longer.
• The Rockies have combined with opponents to hit the over on the total 41 times this season for a 41-58-4 record against the over/under.
• The Rockies have put together a 42-61-0 record ATS this season (covering 40.8% of the time).

Guardians Player Leaders

• Jose Ramirez has 114 hits and an OBP of .372 to go with a slugging percentage of .525. All three of those stats rank first among Cleveland hitters this season. He has a .298 batting average, as well.
• Among qualifying hitters in baseball, his batting average ranks ninth, his on-base percentage ranks 16th, and he is 11th in slugging.
• Ramirez has hit safely in seven games in a row. In his last 10 outings he is hitting .324 with three doubles, a triple, three home runs, seven walks and six RBIs.
• Steven Kwan is batting .285 with 20 doubles, a triple, nine home runs and 39 walks. He's slugging .411 with an on-base percentage of .350.
• Among all qualified, he is 25th in batting average, 46th in on-base percentage and 92nd in slugging percentage.
• Kwan has picked up a hit in five games in a row. During his last five outings he is batting .300 with three home runs, three walks and five RBIs.
• Carlos Santana has collected 77 base hits, an OBP of .317 and a slugging percentage of .339 this season.
• Kyle Manzardo has 16 home runs, 43 RBI and a batting average of .228 this season.
• Manzardo heads into this matchup on a six-game hitting streak. During his last 10 games he is batting .324 with two doubles, three home runs, four walks and 10 RBIs.

Rockies Player Leaders

• Hunter Goodman has racked up a team-high OBP (.326) and slugging percentage (.513), while pacing the Rockies in hits (98, while batting .281).
• Including all qualifying hitters in the majors, his batting average places him 34th, his on-base percentage ranks 75th, and he is 15th in slugging.
• Mickey Moniak is batting .273 with 11 doubles, six triples, 16 home runs and 18 walks. He's slugging .542 with an on-base percentage of .323.
• Jordan Beck has put up a team-high .326 on-base percentage.
• Tyler Freeman is batting .302 with 14 doubles, a triple, a home run and 22 walks.

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