Guardians vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 25

Odds updated as of 6:13 p.m.

Wednesday's slate in the MLB includes a matchup between the Cleveland Guardians and the Cincinnati Reds.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Guardians vs Reds Game Info

• Cleveland Guardians (91-67) vs. Cincinnati Reds (76-82)
• Date: Wednesday, September 25, 2024
• Time: 6:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: BSGL

Guardians vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-146) | CIN: (+124)
• Spread: CLE: -1.5 (+146) | CIN: +1.5 (-176)
• Total: 8 -- Over: (-104) | Under: (-118)

Guardians vs Reds Probable Starting Pitchers

Probable Pitchers: Andrew Walters (Guardians) - 1-0, 0.00 ERA vs Jakob Junis (Reds) - 4-0, 2.61 ERA

The Guardians will give the ball to Andrew Walters (1-0, 0.00 ERA), who is eyeing win No. 2 on the season, and the Reds will counter with Jakob Junis (4-0, 2.61 ERA). Walters did not pitch as the moneyline favorite last season. The Reds have gone 1-3-0 against the spread when Junis starts. The Reds were the moneyline underdog for two Junis starts this season -- they lost both.

Guardians vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (52.6%)

Guardians vs Reds Moneyline

• Looking at the moneyline for Reds-Guardians, Cincinnati is the underdog at +124, and Cleveland is -146 playing at home.

Guardians vs Reds Spread

• The Guardians are hosting the Reds and are favored by 1.5 runs (+146 to cover) on the runline. Cincinnati is -176 to cover.

Guardians vs Reds Over/Under

• The over/under for the Guardians versus Reds contest on Sept. 25 has been set at 8, with -104 odds on the over and -118 odds on the under.

Bet on Cleveland Guardians vs. Cincinnati Reds on FanDuel today!

Guardians vs Reds Betting Trends

• The Guardians have come away with 62 wins in the 94 contests they have been listed as the favorites in this season.
• This year Cleveland has won 24 of 36 games when listed as at least -146 on the moneyline.
• The Guardians and their opponents have gone over the total this season in 70 of their 156 opportunities.
• In 156 games with a line this season, the Guardians have a mark of 84-72-0 against the spread.
• The Reds have been the underdog on the moneyline 83 total times this season. They've finished 38-45 in those games.
• In games it has played as a moneyline underdog with odds of +124 or longer, Cincinnati has gone 17-17 (50%).
• The Reds have combined with opponents to hit the over on the total 72 times this season for a 72-73-7 record against the over/under.
• The Reds have covered 55.9% of their games this season, going 85-67-0 ATS.

Guardians Player Leaders

• Jose Ramirez has 168 hits to go with a slugging percentage of .521, both of which are tops among Cleveland hitters this season. He has a .275 batting average and an on-base percentage of .332.
• Among qualifying hitters in baseball, his batting average ranks 31st, his on-base percentage ranks 50th, and he is 12th in slugging.
• Josh Naylor has 27 doubles, 31 home runs and 57 walks. He's batting .243 and slugging .460 with an on-base percentage of .319.
• His batting average ranks 95th among qualified players, his on-base percentage 81st, and his slugging percentage 39th.
• Steven Kwan leads Cleveland in OBP (.364) this season, fueled by 138 hits.
• Kwan enters this matchup with four games in a row with at least one hit. During his last five outings he is hitting .313 with seven walks.
• Andres Gimenez is batting .255 with a .302 OBP and 63 RBI for Cleveland this season.

Reds Player Leaders

• Elly De La Cruz has 156 hits with a .473 slugging percentage, both team-high numbers for the Reds. He's batting .260 and with an on-base percentage of .341.
• Including all the qualifying hitters in the majors, his batting average ranks 56th, his on-base percentage ranks 36th, and he is 26th in slugging.
• Spencer Steer has 34 doubles, four triples, 20 home runs and 71 walks while hitting .229. He's slugging .412 with an on-base percentage of .324.
• He ranks 116th in batting average, 69th in on-base percentage and 78th in slugging percentage in the majors.
• Jonathan India has put up an on-base percentage of .354, a team-high for the Reds.
• Tyler Stephenson is hitting .262 with 26 doubles, a triple, 19 home runs and 45 walks.

Guardians vs Reds Head to Head

• 9/24/2024: 6-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/12/2024: 4-2 CIN (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/11/2024: 5-3 CLE (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/27/2023: 4-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/26/2023: 11-7 CIN (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/16/2023: 7-2 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/15/2023: 3-0 CLE (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!