Giants vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 11

Odds updated as of 6:11 a.m.

On Monday in MLB, the San Francisco Giants are playing the San Diego Padres.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Giants vs Padres Game Info

• San Francisco Giants (59-59) vs. San Diego Padres (66-52)
• Date: Monday, August 11, 2025
• Time: 9:45 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and SDPA

Giants vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-142) | SD: (+120)
• Spread: SF: -1.5 (+138) | SD: +1.5 (-166)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Giants vs Padres Probable Starting Pitchers

Probable Pitchers: Logan Webb (Giants) - 10-8, 3.24 ERA vs Yu Darvish (Padres) - 1-3, 6.51 ERA

This contest's pitching matchup is set, as the Giants will send Logan Webb (10-8) to the mound, while Yu Darvish (1-3) will answer the bell for the Padres. Webb and his team have a record of 9-15-0 against the spread when he starts. Webb's team has been victorious in 45.5% of the games he's started as the moneyline favorite with a record of 10-12. The Padres have a 3-2-0 record against the spread in Darvish's starts. The Padres were named the moneyline underdog for two Darvish starts this season -- they split the games.

Giants vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (57.4%)

Giants vs Padres Moneyline

• San Diego is a +120 underdog on the moneyline, while San Francisco is a -142 favorite at home.

Giants vs Padres Spread

• The Padres are at the Giants, and are +1.5 on the runline. The Padres are +138 to cover the spread, and the Giants are -166.

Giants vs Padres Over/Under

• The Giants-Padres game on Aug. 11 has been given an over/under of 7.5 runs. The over is set at -110 and the under at -110.

Bet on San Francisco Giants vs. San Diego Padres on FanDuel today!

Giants vs Padres Betting Trends

• The Giants have won in 38, or 51.4%, of the 74 contests they have been named as odds-on favorites in this year.
• This season San Francisco has come away with a win 24 times in 46 chances when named as a favorite of at least -142 on the moneyline.
• The Giants and their opponents have gone over the total this season in 53 of their 118 opportunities.
• The Giants have posted a record of 50-68-0 against the spread this season.
• The Padres have won 49% of the games this season they were the moneyline underdog (25-26).
• San Diego is 12-15 (winning 44.4% of its games) when playing as a moneyline underdog of +120 or longer.
• The Padres have had an over/under set by oddsmakers 116 times, and have combined with opponents to go over the total in 50 of those games (50-63-3).
• The Padres have a 63-53-0 record ATS this season.

Giants Player Leaders

• Rafael Devers leads San Francisco in OBP (.382) and total hits (113) this season. He's batting .256 batting average while slugging .467.
• Among qualified hitters in MLB, he ranks 84th in batting average, 11th in on-base percentage, and 45th in slugging.
• Jung Hoo Lee has 27 doubles, nine triples, six home runs and 38 walks. He's batting .256 and slugging .405 with an on-base percentage of .322.
• He ranks 84th in batting average, 91st in on-base percentage and 99th in slugging among qualifying batters.
• Willy Adames has collected 100 base hits, an OBP of .316 and a slugging percentage of .404 this season.
• Heliot Ramos leads San Francisco in slugging percentage (.416) thanks to 35 extra-base hits.
• Ramos heads into this game on a two-game hitting streak. During his last five outings he is hitting .300 with three walks.

Padres Player Leaders

• Manny Machado has totaled 135 hits with a .492 slugging percentage, both team-high numbers for the Padres. He's batting .297 and with an on-base percentage of .358.
• Including all the qualifying hitters in MLB, he is 10th in batting average, 30th in on-base percentage and 24th in slugging percentage.
• Fernando Tatis Jr. is hitting .262 with 19 doubles, two triples, 17 home runs and 66 walks. He's slugging .431 with an on-base percentage of .365.
• He is currently 69th in batting average, 20th in on-base percentage and 75th in slugging percentage among all qualifying hitters.
• Luis Arraez has a team-best .403 slugging percentage.
• Xander Bogaerts is hitting .271 with 25 doubles, 10 home runs and 46 walks.

Giants vs Padres Head to Head

• 6/5/2025: 3-2 SF (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/4/2025: 6-5 SF (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/3/2025: 3-2 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/2/2025: 1-0 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 4/30/2025: 5-3 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/29/2025: 7-4 SD (Favorite: Giants, Spread: -1.5, Total: 6.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/15/2024: 4-3 SD (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/14/2024: 8-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 9/13/2024: 5-0 SD (Favorite: Padres, Spread: -1.5, Total: 6.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/8/2024: 7-6 SF (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!