Giants vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 11

Odds updated as of 9:11 p.m.

Monday's slate in the MLB includes a matchup between the San Francisco Giants and the San Diego Padres.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Giants vs Padres Game Info

• San Francisco Giants (59-59) vs. San Diego Padres (66-52)
• Date: Monday, August 11, 2025
• Time: 9:45 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and SDPA

Giants vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-130) | SD: (+110)
• Spread: SF: -1.5 (+164) | SD: +1.5 (-200)
• Total: 7.5 -- Over: (-100) | Under: (-122)

Giants vs Padres Probable Starting Pitchers

Probable Pitchers: Logan Webb (Giants) - 10-8, 3.24 ERA vs Yu Darvish (Padres) - 1-3, 6.51 ERA

This contest's pitching matchup is set, as the Giants will send Logan Webb (10-8) to the mound, while Yu Darvish (1-3) will answer the bell for the Padres. Webb and his team have a record of 9-15-0 against the spread when he starts. Webb's team is 10-12 this season when he starts and they are the moneyline favorite. The Padres are 3-2-0 against the spread when Darvish starts. The Padres were the moneyline underdog for two Darvish starts this season -- they split the games.

Giants vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (57.1%)

Giants vs Padres Moneyline

• Looking at the moneyline for Giants-Padres, San Francisco is the favorite at -130, and San Diego is +110 playing on the road.

Giants vs Padres Spread

• The Padres are at the Giants, and are +1.5 on the runline. The Padres are +164 to cover the spread, and the Giants are -200.

Giants vs Padres Over/Under

• An over/under of 7.5 has been set for Giants-Padres on Aug. 11, with the over being -100 and the under -122.

Bet on San Francisco Giants vs. San Diego Padres on FanDuel today!

Giants vs Padres Betting Trends

• The Giants have been favorites in 74 games this season and have come away with the win 38 times (51.4%) in those contests.
• This season San Francisco has been victorious 30 times in 57 chances when named as a favorite of at least -130 on the moneyline.
• Contests with the Giants have gone over the total set by oddsmakers in 53 of 118 chances this season.
• The Giants are 50-68-0 against the spread in their 118 games that had a posted line this season.
• The Padres have won 25 of the 51 games they were the moneyline underdog this season (49%).
• San Diego is 19-20 (winning 48.7% of its games) when playing as a moneyline underdog of +110 or longer.
• In the 116 games oddsmakers have set an over/under for the Padres, they have combined with opponents to go over the total 50 times (50-63-3).
• The Padres have put together a 63-53-0 record ATS this season (covering 54.3% of the time).

Giants Player Leaders

• Rafael Devers leads San Francisco in OBP (.382) and total hits (113) this season. He's batting .256 batting average while slugging .467.
• He ranks 84th in batting average, 11th in on-base percentage, and 45th in slugging among all qualifying hitters in MLB.
• Jung Hoo Lee is batting .256 with 27 doubles, nine triples, six home runs and 38 walks. He's slugging .405 with an on-base percentage of .322.
• Among qualifying hitters, he ranks 84th in batting average, 91st in on-base percentage and 99th in slugging percentage.
• Willy Adames has 100 hits this season and has a slash line of .229/.316/.404.
• Heliot Ramos leads San Francisco in slugging percentage (.416) thanks to 35 extra-base hits.
• Ramos brings a two-game hitting streak into this game. In his last five games he is batting .300 with three walks.

Padres Player Leaders

• Manny Machado has accumulated a slugging percentage of .492 and has 135 hits, both team-best numbers for the Padres. He's batting .297 and with an on-base percentage of .358.
• Including all qualified hitters in the majors, he ranks 10th in batting average, 30th in on-base percentage and 24th in slugging percentage.
• Fernando Tatis Jr. has 19 doubles, two triples, 17 home runs and 66 walks while hitting .262. He's slugging .431 with an on-base percentage of .365.
• His batting average is 69th among all qualified players, his on-base percentage is 20th, and he is 75th in slugging.
• Luis Arraez has put up a slugging percentage of .403, a team-high for the Padres.
• Xander Bogaerts is hitting .271 with 25 doubles, 10 home runs and 46 walks.

Giants vs Padres Head to Head

• 6/5/2025: 3-2 SF (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/4/2025: 6-5 SF (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/3/2025: 3-2 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/2/2025: 1-0 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 4/30/2025: 5-3 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/29/2025: 7-4 SD (Favorite: Giants, Spread: -1.5, Total: 6.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/15/2024: 4-3 SD (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/14/2024: 8-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 9/13/2024: 5-0 SD (Favorite: Padres, Spread: -1.5, Total: 6.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/8/2024: 7-6 SF (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)

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