Dodgers vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for May 20

Odds updated as of 4:11 a.m.

MLB action on Wednesday includes the Los Angeles Dodgers playing the San Diego Padres.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Dodgers vs Padres Game Info

• Los Angeles Dodgers (30-19) vs. San Diego Padres (29-19)
• Date: Wednesday, May 20, 2026
• Time: 8:40 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and SportsNet LA

Dodgers vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-178) | SD: (+150)
• Spread: LAD: -1.5 (+100) | SD: +1.5 (-120)
• Total: 7.5 -- Over: (-104) | Under: (-118)

Dodgers vs Padres Probable Starting Pitchers

Probable Pitchers: Shohei Ohtani (Dodgers) - 3-2, 0.82 ERA vs Randy Vasquez (Padres) - 5-1, 2.68 ERA

The Dodgers will give the nod to Shohei Ohtani (3-2) versus the Padres and Randy Vasquez (5-1). When Ohtani starts, his team is 3-4-0 against the spread this season. Ohtani's team has been victorious in 42.9% of the games he's started as the moneyline favorite with a record of 3-4. The Padres have a 7-2-0 record against the spread in Vasquez's starts. The Padres were the moneyline underdog for two Vasquez starts this season -- they won both.

Dodgers vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (60.1%)

Dodgers vs Padres Moneyline

• Los Angeles is the favorite, -178 on the moneyline, while San Diego is a +150 underdog despite being at home.

Dodgers vs Padres Spread

• The Padres are at +1.5 on the runline against the Dodgers. The Padres are -120 to cover the spread, and the Dodgers are +100.

Dodgers vs Padres Over/Under

• A combined run total of 7.5 has been set for Dodgers-Padres on May 20, with the over at -104 and the under at -118.

Bet on Los Angeles Dodgers vs. San Diego Padres on FanDuel today!

Dodgers vs Padres Betting Trends

• The Dodgers have won in 30, or 61.2%, of the 49 contests they have been named as odds-on favorites in this year.
• This season Los Angeles has been victorious 17 times in 29 chances when named as a favorite of at least -178 on the moneyline.
• Contests with the Dodgers have gone over the total set by bookmakers in 22 of 49 chances this season.
• The Dodgers are 24-25-0 against the spread in their 49 games with a line set by sportsbooks this season.
• The Padres have gone 12-9 in games they were the underdog on the moneyline (winning 57.1% of those games).
• San Diego has yet to play as a moneyline underdog of +150 or longer.
• The Padres have played in 48 games with an over/under set, and have combined with opponents to go over the total 21 times (21-26-1).
• The Padres have a 28-20-0 record ATS this season (covering 58.3% of the time).

Dodgers Player Leaders

• Andy Pages leads Los Angeles with a slugging percentage of .506, fueled by 18 extra-base hits. He has a .294 batting average and an on-base percentage of .343.
• Among the qualifying hitters in baseball, his batting average ranks 20th, his on-base percentage ranks 69th, and he is 23rd in slugging.
• Ohtani leads Los Angeles with an OBP of .399 this season while batting .272 with 33 walks and 31 runs scored. He's slugging .473.
• He is 46th in batting average, seventh in on-base percentage and 42nd in slugging among qualifying hitters.
• Ohtani brings a five-game streak with at least one hit into this one. In his last five games he is hitting .526 with four doubles, a triple, five walks and eight RBIs.
• Kyle Tucker has collected 43 base hits, an OBP of .347 and a slugging percentage of .393 this season.
• Max Muncy leads Los Angeles in total hits (41) this season while batting .261 with 17 extra-base hits.

Padres Player Leaders

• Xander Bogaerts has put up an on-base percentage of .324, a slugging percentage of .394, and has 43 hits, all club-highs for the Padres (while batting .253).
• Including all qualifying hitters in MLB, he ranks 82nd in batting average, 95th in on-base percentage and 93rd in slugging percentage.
• Gavin Sheets is hitting .254 with 10 doubles, nine home runs and 16 walks. He's slugging .538 with an on-base percentage of .340.
• Manny Machado is batting .182 with five doubles, seven home runs and 23 walks.
• Miguel Andujar is hitting .299 with 11 doubles, two triples, five home runs and four walks.

Dodgers vs Padres Head to Head

• 5/19/2026: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/18/2026: 1-0 SD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/24/2025: 8-2 LAD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/23/2025: 5-1 SD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/22/2025: 2-1 SD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/17/2025: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/16/2025: 6-0 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/15/2025: 3-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/19/2025: 5-3 SD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 6/18/2025: 4-3 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -198, Underdog Moneyline: +166)

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