Dodgers vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for May 20

Odds updated as of 8:12 p.m.

On Wednesday in MLB, the Los Angeles Dodgers are up against the San Diego Padres.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Dodgers vs Padres Game Info

• Los Angeles Dodgers (30-19) vs. San Diego Padres (29-19)
• Date: Wednesday, May 20, 2026
• Time: 8:40 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and SportsNet LA

Dodgers vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-196) | SD: (+164)
• Spread: LAD: -1.5 (-110) | SD: +1.5 (-110)
• Total: 7.5 -- Over: (+104) | Under: (-128)

Dodgers vs Padres Probable Starting Pitchers

Probable Pitchers: Shohei Ohtani (Dodgers) - 3-2, 0.82 ERA vs Randy Vasquez (Padres) - 5-1, 2.68 ERA

This contest's pitching matchup is set, as the Dodgers will send Shohei Ohtani (3-2) to the mound, while Randy Vasquez (5-1) will answer the bell for the Padres. Ohtani's team is 3-4-0 against the spread this season in his starts. When Ohtani starts a game and his team is the favorite on the moneyline, they have a record of 3-4. The Padres are 7-2-0 against the spread when Vasquez starts. The Padres were the underdog on the moneyline for two Vasquez starts this season -- they won both.

Dodgers vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (60.3%)

Dodgers vs Padres Moneyline

• Los Angeles is the favorite, -196 on the moneyline, while San Diego is a +164 underdog despite being at home.

Dodgers vs Padres Spread

• The Dodgers are at the Padres and are favored by 1.5 runs (-110 to cover) on the runline. San Diego is -110 to cover.

Dodgers vs Padres Over/Under

• The Dodgers-Padres contest on May 20 has been given an over/under of 7.5 runs. The over is set at +104 and the under at -128.

Bet on Los Angeles Dodgers vs. San Diego Padres on FanDuel today!

Dodgers vs Padres Betting Trends

• The Dodgers have won in 30, or 61.2%, of the 49 contests they have been named as odds-on favorites in this year.
• This season Los Angeles has been victorious 14 times in 22 chances when named as a favorite of at least -196 on the moneyline.
• The Dodgers and their opponents have gone over the total this season in 22 of their 49 opportunities.
• The Dodgers are 24-25-0 against the spread in their 49 games with a line set by sportsbooks this season.
• The Padres have been the underdog on the moneyline 21 total times this season. They've finished 12-9 in those games.
• San Diego has not yet played as a moneyline underdog of +164 or longer.
• The Padres have played in 48 games with an over/under set, and have combined with opponents to go over the total 21 times (21-26-1).
• The Padres have collected a 28-20-0 record ATS this season (covering 58.3% of the time).

Dodgers Player Leaders

• Andy Pages leads Los Angeles with a slugging percentage of .506, fueled by 18 extra-base hits. He has a .294 batting average and an on-base percentage of .343.
• Among all qualified hitters in the majors, he ranks 19th in batting average, 70th in on-base percentage, and 23rd in slugging.
• Ohtani has 46 hits this season and a team-best OBP of .399. He's batting .272 and slugging .473.
• He ranks 49th in batting average, seventh in on-base percentage and 44th in slugging in MLB.
• Ohtani heads into this matchup looking to extend his five-game hit streak. During his last five outings he is batting .526 with four doubles, a triple, five walks and eight RBIs.
• Kyle Tucker has 43 hits this season and has a slash line of .249/.347/.393.
• Max Muncy leads Los Angeles in total hits (41) this season while batting .261 with 17 extra-base hits.

Padres Player Leaders

• Xander Bogaerts has racked up 43 hits with a .324 on-base percentage and a .394 slugging percentage, all club-highs for the Padres. He's batting .253.
• Including all qualified players in the big leagues, he is 83rd in batting average, 94th in on-base percentage and 94th in slugging percentage.
• Gavin Sheets is batting .254 with 10 doubles, nine home runs and 16 walks. He's slugging .538 with an on-base percentage of .340.
• Manny Machado is hitting .182 with five doubles, seven home runs and 23 walks.
• Miguel Andujar is batting .299 with 11 doubles, two triples, five home runs and four walks.

Dodgers vs Padres Head to Head

• 5/19/2026: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/18/2026: 1-0 SD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/24/2025: 8-2 LAD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/23/2025: 5-1 SD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/22/2025: 2-1 SD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/17/2025: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/16/2025: 6-0 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/15/2025: 3-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/19/2025: 5-3 SD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 6/18/2025: 4-3 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -198, Underdog Moneyline: +166)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!