Dodgers vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 6

Odds updated as of 4:14 a.m.

The Los Angeles Dodgers are among the MLB teams busy on Wednesday, versus the St. Louis Cardinals.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Dodgers vs Cardinals Game Info

• Los Angeles Dodgers (66-48) vs. St. Louis Cardinals (57-58)
• Date: Wednesday, August 6, 2025
• Time: 4:10 p.m. ET
• Venue: Dodger Stadium -- Los Angeles, California
• Coverage: MLB Network, SportsNet LA, and FDSMW

Dodgers vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-184) | STL: (+154)
• Spread: LAD: -1.5 (+104) | STL: +1.5 (-125)
• Total: 9 -- Over: (-114) | Under: (-106)

Dodgers vs Cardinals Probable Starting Pitchers

Probable Pitchers: Shohei Ohtani (Dodgers) - 0-0, 2.40 ERA vs Matthew Liberatore (Cardinals) - 6-9, 3.96 ERA

The Dodgers will give the ball to Shohei Ohtani and the Cardinals will turn to Matthew Liberatore (6-9, 3.96 ERA). Ohtani's team is 3-4-0 against the spread in his starts this season. Ohtani's team has won 57.1% of his starts when they are favored on the moneyline (4-3). The Cardinals are 9-11-0 against the spread when Liberatore starts. The Cardinals have a 5-2 record in Liberatore's seven starts this season when they were the underdog on the moneyline.

Dodgers vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (62.8%)

Dodgers vs Cardinals Moneyline

• Looking at the moneyline for Dodgers-Cardinals, Los Angeles is the favorite at -184, and St. Louis is +154 playing on the road.

Dodgers vs Cardinals Spread

• The Cardinals are at +1.5 on the runline against the Dodgers. The Cardinals are -125 to cover the spread, and the Dodgers are +104.

Dodgers vs Cardinals Over/Under

• A combined run total of 9 has been set for Dodgers-Cardinals on Aug. 6, with the over at -114 and the under at -106.

Bet on Los Angeles Dodgers vs. St. Louis Cardinals on FanDuel today!

Dodgers vs Cardinals Betting Trends

• The Dodgers have been victorious in 58, or 59.8%, of the 97 contests they have been chosen as favorites in this season.
• This year Los Angeles has won 30 of 44 games when listed as at least -184 on the moneyline.
• The Dodgers' games have gone over the total in 56 of their 112 opportunities.
• In 112 games with a line this season, the Dodgers have a mark of 47-65-0 against the spread.
• The Cardinals have won 29 of the 59 games they were the moneyline underdog this season (49.2%).
• When it has played as a moneyline underdog with odds of +154 or longer, St. Louis has a 1-5 record (winning only 16.7% of its games).
• The Cardinals have played in 112 games with a set over/under, and have combined with their opponents to go over the total 57 times (57-50-5).
• The Cardinals have put together a 58-54-0 record ATS this season (covering 51.8% of the time).

Dodgers Player Leaders

• Ohtani leads Los Angeles in slugging percentage (.601) and total hits (121) this season. He's batting .276 with an on-base percentage of .380.
• Among qualifying hitters in MLB, his batting average ranks 39th, his on-base percentage ranks 10th, and he is second in slugging.
• Ohtani hopes to build on a five-game hitting streak in this matchup. During his last five outings he is hitting .421 with two doubles and four walks.
• Mookie Betts is batting .236 with 16 doubles, a triple, 11 home runs and 43 walks. He's slugging .361 with an on-base percentage of .308.
• He is 123rd in batting average, 117th in on-base percentage and 142nd in slugging among qualified hitters.
• Will Smith leads Los Angeles with an OBP of .420 this season while batting .321 with 51 walks and 54 runs scored.
• Freddie Freeman has been key for Los Angeles with 116 hits, an OBP of .373 plus a slugging percentage of .489.

Cardinals Player Leaders

• Brendan Donovan has racked up an on-base percentage of .351 and a slugging percentage of .405. Both lead the Cardinals. He's batting .279.
• Including all the qualifying hitters in the big leagues, he ranks 32nd in batting average, 44th in on-base percentage and 101st in slugging percentage.
• Alec Burleson is batting .278 with 19 doubles, 14 home runs and 30 walks. He's slugging .450 with an on-base percentage of .332.
• Including all qualifying hitters, he is 35th in batting average, 68th in on-base percentage and 63rd in slugging percentage.
• Willson Contreras has totaled 103 hits, a team-high for the Cardinals.
• Masyn Winn has 24 doubles, eight home runs and 28 walks while hitting .267.

Dodgers vs Cardinals Head to Head

• 8/5/2025: 12-6 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 8/4/2025: 3-2 STL (Favorite: Dodgers, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 6/8/2025: 7-3 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/7/2025: 2-1 STL (Favorite: Dodgers, Spread: -1.5, Total: 8, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/6/2025: 5-0 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/18/2024: 2-1 LAD (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/17/2024: 5-2 STL (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/16/2024: 7-6 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 3/31/2024: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 3/30/2024: 6-5 STL (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -235, Underdog Moneyline: +194)

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