Diamondbacks vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for May 5

Odds updated as of 5:12 a.m.

In MLB action on Tuesday, the Arizona Diamondbacks play the Pittsburgh Pirates.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Diamondbacks vs Pirates Game Info

• Arizona Diamondbacks (16-17) vs. Pittsburgh Pirates (19-16)
• Date: Tuesday, May 5, 2026
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: Dbacks.TV and SportsNet PT

Diamondbacks vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-130) | PIT: (+110)
• Spread: ARI: -1.5 (+162) | PIT: +1.5 (-196)
• Total: 9 -- Over: (-105) | Under: (-115)

Diamondbacks vs Pirates Probable Starting Pitchers

Probable Pitchers: Eduardo Rodríguez (Diamondbacks) - 2-0, 3.03 ERA vs Bubba Chandler (Pirates) - 1-3, 4.97 ERA

This contest's pitching matchup is set, as the Diamondbacks will send Eduardo Rodriguez (2-0) to the mound, while Bubba Chandler (1-3) will take the ball for the Pirates. When Rodriguez starts, his team is 5-1-0 against the spread this season. Rodriguez's team won his only start as a favorite this season. The Pirates are 3-3-0 ATS in Chandler's six starts that had a set spread. The Pirates were the moneyline underdog for two Chandler starts this season -- they lost both.

Diamondbacks vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (50.9%)

Diamondbacks vs Pirates Moneyline

• Pittsburgh is a +110 underdog on the moneyline, while Arizona is a -130 favorite at home.

Diamondbacks vs Pirates Spread

• The Pirates are +1.5 on the spread (-196 to cover), and Arizona is +162 to cover the runline.

Diamondbacks vs Pirates Over/Under

• A total of 9 runs has been set for the Diamondbacks-Pirates contest on May 5, with the over available at -105 and the under at -115.

Bet on Arizona Diamondbacks vs. Pittsburgh Pirates on FanDuel today!

Diamondbacks vs Pirates Betting Trends

• The Diamondbacks have won in six of the nine contests they have been named as odds-on favorites in this year.
• This season Arizona has been victorious three times in five chances when named as a favorite of at least -130 on the moneyline.
• The Diamondbacks' games have gone over the total in 20 of their 33 opportunities.
• The Diamondbacks are 21-12-0 against the spread in their 33 games with a line set by sportsbooks this season.
• The Pirates have been the moneyline underdog 13 total times this season. They've finished 5-8 in those games.
• Pittsburgh has gone 4-4 when playing as a moneyline underdog with odds of +110 or longer (50%).
• In the 34 games bookmakers have set an over/under for the Pirates, they have combined with opponents to go over the total 19 times (19-15-0).
• The Pirates have collected an 18-16-0 record ATS this season (covering 52.9% of the time).

Diamondbacks Player Leaders

• Ildemaro Vargas has 39 hits and an OBP of .406 to go with a slugging percentage of .657. All three of those stats lead Arizona hitters this season. He has a .382 batting average, as well.
• Among qualified hitters in baseball, his batting average ranks first, his on-base percentage ranks 13th, and he is fourth in slugging.
• Corbin Carroll has seven doubles, four triples, four home runs and 17 walks. He's batting .273 and slugging .518 with an on-base percentage of .372.
• Among qualified hitters, he is 48th in batting average, 38th in on-base percentage and 26th in slugging percentage.
• Geraldo Perdomo is batting .245 with a .402 slugging percentage and nine RBI this year.
• Perdomo takes a three-game hitting streak into this game. During his last five outings he is batting .222 with a double, a home run, four walks and three RBIs.
• Nolan Arenado has been key for Arizona with 30 hits, an OBP of .310 plus a slugging percentage of .440.
• Arenado has safely hit in three straight games. In his last five games he is hitting .235 with a double, a home run, a walk and three RBIs.

Pirates Player Leaders

• Oneil Cruz is batting .264 with six doubles, nine home runs and 11 walks. He's slugging .500 with an on-base percentage of .322.
• He is 60th in batting average, 104th in on-base percentage and 30th in slugging percentage among all qualified hitters in MLB.
• Cruz enters this matchup on a four-game hitting streak. In his last five games he is hitting .261 with a double, two walks and three RBIs.
• Ryan O'Hearn is batting .308 with five doubles, five home runs and 16 walks. He's slugging .475 with an on-base percentage of .393.
• He ranks 20th in batting average, 17th in on-base percentage and 42nd in slugging percentage in the big leagues.
• Bryan Reynolds a has .404 on-base percentage to lead the Pirates.
• Brandon Lowe paces his team with 28 hits.

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