Diamondbacks vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for May 26

Odds updated as of 8:15 p.m.

On Monday in MLB, the Arizona Diamondbacks are playing the Pittsburgh Pirates.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Diamondbacks vs Pirates Game Info

• Arizona Diamondbacks (26-27) vs. Pittsburgh Pirates (19-35)
• Date: Monday, May 26, 2025
• Time: 8:10 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: MLB Network, ARID, and SportsNet PT

Diamondbacks vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-190) | PIT: (+160)
• Spread: ARI: -1.5 (+102) | PIT: +1.5 (-122)
• Total: 9.5 -- Over: (-100) | Under: (-122)

Diamondbacks vs Pirates Probable Starting Pitchers

Probable Pitchers: Ryne Nelson (Diamondbacks) - 1-1, 4.60 ERA vs Andrew Heaney (Pirates) - 3-3, 2.91 ERA

The Diamondbacks will look to Ryne Nelson (1-1) against the Pirates and Andrew Heaney (3-3). Nelson has a record of 2-0-0 ATS in two starts with a spread this season. Nelson's team lost his only start as a favorite this season. The Pirates have gone 4-5-0 against the spread when Heaney starts. The Pirates have a 3-4 record in Heaney's seven starts this season when they were the underdog on the moneyline.

Diamondbacks vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (71.9%)

Diamondbacks vs Pirates Moneyline

• Arizona is the favorite, -190 on the moneyline, while Pittsburgh is a +160 underdog on the road.

Diamondbacks vs Pirates Spread

• The Pirates are at +1.5 on the runline against the Diamondbacks. The Pirates are -122 to cover the spread, and the Diamondbacks are +102.

Diamondbacks vs Pirates Over/Under

• The over/under for the Diamondbacks versus Pirates game on May 26 has been set at 9.5, with -100 odds on the over and -122 odds on the under.

Bet on Arizona Diamondbacks vs. Pittsburgh Pirates on FanDuel today!

Diamondbacks vs Pirates Betting Trends

• The Diamondbacks have won in 17, or 53.1%, of the 32 contests they have been named as odds-on favorites in this year.
• This season Arizona has been victorious two times in three chances when named as a favorite of at least -190 on the moneyline.
• Contests with the Diamondbacks have gone over the total set by oddsmakers in 23 of 52 chances this season.
• The Diamondbacks are 24-28-0 against the spread in their 52 games that had a posted line this season.
• The Pirates are 13-23 in games they were listed as the moneyline underdog (winning 36.1% of those games).
• Pittsburgh has a 3-4 record (winning 42.9% of its games) when playing as a moneyline underdog of +160 or longer.
• The Pirates have had an over/under set by bookmakers 52 times, and have combined with opponents to go over the total in 20 of those games (20-29-3).
• The Pirates have a 22-30-0 record against the spread this season.

Diamondbacks Player Leaders

• Geraldo Perdomo leads Arizona in OBP (.401) this season, fueled by 55 hits. He has a .304 batting average and a slugging percentage of .475.
• Among qualified hitters, he ranks 14th in batting average, his on-base percentage ranks seventh, and he is 38th in slugging.
• Corbin Carroll leads Arizona with 58 hits and a team-best slugging percentage of .566. He's batting .265 with an on-base percentage of .337.
• Among qualified hitters, he is 67th in batting average, 68th in on-base percentage and seventh in slugging percentage.
• Josh Naylor has collected 57 base hits, an OBP of .350 and a slugging percentage of .439 this season.
• Naylor enters this game with four games in a row with at least one hit. During his last five outings he is hitting .190 with a double, a triple and two RBIs.
• Eugenio Suarez is batting .230 with a .312 OBP and 40 RBI for Arizona this season.
• Suarez takes a four-game hitting streak into this matchup. During his last five outings he is batting .368 with a double and two RBIs.

Pirates Player Leaders

• Oneil Cruz has racked up 38 hits, a team-best for the Pirates. He's batting .236 and slugging .491 with an on-base percentage of .362.
• Including all qualified hitters in the majors, he is 112th in batting average, 37th in on-base percentage and 32nd in slugging percentage.
• Cruz heads into this game on a five-game hitting streak. In his last five games he is batting .350 with a double, a triple, three home runs, three walks and five RBIs.
• Andrew McCutchen's .368 on-base percentage leads his team. He has a batting average of .260 while slugging .370.
• He is 71st in batting average, 32nd in on-base percentage and 121st in slugging percentage in MLB.
• Bryan Reynolds is batting .212 with seven doubles, six home runs and 19 walks.
• Adam Frazier has six doubles, two home runs and 14 walks while hitting .253.

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