Phillies vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for July 22

Odds updated as of 7:14 a.m.

The Philadelphia Phillies will face the Boston Red Sox in MLB action on Tuesday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding this game.

Phillies vs Red Sox Game Info

• Philadelphia Phillies (57-43) vs. Boston Red Sox (54-48)
• Date: Tuesday, July 22, 2025
• Time: 6:45 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: TBS, NBCS-PH, and NESN

Phillies vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-198) | BOS: (+166)
• Spread: PHI: -1.5 (-100) | BOS: +1.5 (-120)
• Total: 8.5 -- Over: (-112) | Under: (-108)

Phillies vs Red Sox Probable Starting Pitchers

Probable Pitchers: Cristopher Sanchez (Phillies) - 8-2, 2.43 ERA vs Richard Fitts (Red Sox) - 1-3, 4.28 ERA

This contest's pitching matchup is set, as the Phillies will send Cristopher Sanchez (8-2) to the mound, while Richard Fitts (1-3) will take the ball for the Red Sox. Sanchez's team is 11-8-0 against the spread in his starts this season. Sanchez's team has been victorious in 81.2% of the games he's started as the moneyline favorite with a record of 13-3. When Fitts starts, the Red Sox have gone 2-5-0 against the spread. The Red Sox were the moneyline underdog for three Fitts starts this season -- they lost every game.

Phillies vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (66.3%)

Phillies vs Red Sox Moneyline

• Philadelphia is the favorite, -198 on the moneyline, while Boston is a +166 underdog on the road.

Phillies vs Red Sox Spread

• The Red Sox are at +1.5 on the runline against the Phillies. The Red Sox are -120 to cover the spread, and the Phillies are -100.

Phillies vs Red Sox Over/Under

• An over/under of 8.5 has been set for Phillies-Red Sox on July 22, with the over being -112 and the under -108.

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Phillies vs Red Sox Betting Trends

• The Phillies have been favorites in 75 games this season and have come away with the win 49 times (65.3%) in those contests.
• This year Philadelphia has won 16 of 18 games when listed as at least -198 on the moneyline.
• The Phillies and their opponents have gone over in 37 of their 94 games with a total set by sportsbooks this season.
• The Phillies have posted a record of 47-47-0 against the spread this season.
• The Red Sox have been the underdog on the moneyline 33 total times this season. They've gone 14-19 in those games.
• Boston is 1-2 (winning just 33.3% of its games) when playing as a moneyline underdog of +166 or longer.
• The Red Sox have played in 101 games with an over/under set, and have combined with their opponents to go over the total 47 times (47-50-4).
• The Red Sox have collected a 55-46-0 record against the spread this season (covering 54.5% of the time).

Phillies Player Leaders

• Kyle Schwarber has 91 hits, which leads Philadelphia hitters this season, while batting .248 with 47 extra-base hits. He has an on-base percentage of .377 and a slugging percentage of .553.
• Among qualifying hitters in MLB, he ranks 105th in batting average, 14th in on-base percentage, and 10th in slugging.
• Trea Turner has hit 11 homers this season while driving in 41 runs. He's batting .286 this season and slugging .425 with an on-base percentage of .343.
• Among all qualified, he ranks 22nd in batting average, 59th in on-base percentage and 80th in slugging percentage.
• Bryce Harper has 73 hits this season and a team-best OBP of .379.
• Nick Castellanos is batting .270 with a .312 OBP and 53 RBI for Philadelphia this season.

Red Sox Player Leaders

• Jarren Duran has a .323 on-base percentage and a .433 slugging percentage, both team-high averages for the Red Sox. He's batting .257.
• Including all the qualified hitters in the big leagues, his batting average places him 84th, his on-base percentage is 92nd, and he is 73rd in slugging.
• Ceddanne Rafaela has collected 90 hits to lead his team. He has a batting average of .270 while slugging .471 with an on-base percentage of .311.
• Including all qualified players, he is 55th in batting average, 119th in on-base percentage and 41st in slugging percentage.
• Wilyer Abreu is hitting .253 with 11 doubles, 20 home runs and 31 walks.
• Trevor Story is hitting .252 with 13 doubles, 15 home runs and 19 walks.

Phillies vs Red Sox Head to Head

• 7/21/2025: 3-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 6/13/2024: 9-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/12/2024: 8-6 BOS (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 6/11/2024: 4-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/7/2023: 6-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 10, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/6/2023: 7-4 BOS (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/5/2023: 5-3 BOS (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -166, Underdog Moneyline: +140)

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