Diamondbacks vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 19

Odds updated as of 6:11 a.m.

The Arizona Diamondbacks are among the MLB squads busy on Tuesday, up against the Cleveland Guardians.

All the info you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Diamondbacks vs Guardians Game Info

• Arizona Diamondbacks (60-66) vs. Cleveland Guardians (64-60)
• Date: Tuesday, August 19, 2025
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: MLB Network, ARID, and CLEG

Diamondbacks vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-116) | CLE: (-102)
• Spread: ARI: +1.5 (-176) | CLE: -1.5 (+146)
• Total: 9 -- Over: (-105) | Under: (-115)

Diamondbacks vs Guardians Probable Starting Pitchers

Probable Pitchers: Eduardo Rodríguez (Diamondbacks) - 5-7, 5.40 ERA vs Tanner Bibee (Guardians) - 9-9, 4.48 ERA

This contest's pitching matchup is set, as the Diamondbacks will send Eduardo Rodriguez (5-7) to the mound, while Tanner Bibee (9-9) will get the nod for the Guardians. Rodríguez's team is 7-13-0 against the spread in his starts this season. Rodriguez's team has a record of 6-7 this season when he starts and they are the favorite on the moneyline. The Guardians are 14-9-0 ATS in Bibee's 23 starts that had a set spread. The Guardians have been the moneyline underdog in 10 of Bibee's starts this season, and they went 4-6 in those matchups.

Diamondbacks vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (60.9%)

Diamondbacks vs Guardians Moneyline

• Looking at the moneyline for Diamondbacks-Guardians, Arizona is the favorite at -116, and Cleveland is -102 playing on the road.

Diamondbacks vs Guardians Spread

• The Guardians are 1.5-run favorites against the spread for this matchup with the Diamondbacks. The Guardians are +146 to cover, while the Diamondbacks are -176 to cover as a 1.5-run underdog on the runline.

Diamondbacks vs Guardians Over/Under

• The Diamondbacks-Guardians game on Aug. 19 has been given an over/under of 9 runs. The over is set at -105 and the under at -115.

Bet on Arizona Diamondbacks vs. Cleveland Guardians on FanDuel today!

Diamondbacks vs Guardians Betting Trends

• The Diamondbacks have been chosen as favorites in 74 games this year and have walked away with the win 37 times (50%) in those games.
• This season Arizona has been victorious 32 times in 64 chances when named as a favorite of at least -116 on the moneyline.
• The Diamondbacks and their opponents have gone over the total this season in 60 of their 122 opportunities.
• The Diamondbacks are 57-65-0 against the spread in their 122 games with a line set by sportsbooks this season.
• The Guardians have been the moneyline underdog 66 total times this season. They've gone 29-37 in those games.
• Cleveland is 24-31 (winning 43.6% of its games) when it has played as a moneyline underdog of -102 or longer.
• The Guardians have played in 121 games with an over/under set, and have combined with opponents to go over the total 55 times (55-62-4).
• The Guardians have covered 52.1% of their games this season, going 63-58-0 against the spread.

Diamondbacks Player Leaders

• Geraldo Perdomo leads Arizona with a slugging percentage of .441, fueled by 42 extra-base hits. He has a .287 batting average and an on-base percentage of .388.
• Among qualifying hitters in MLB, he ranks 23rd in batting average, seventh in on-base percentage, and 74th in slugging.
• Perdomo has picked up at least one hit in three games in a row. During his last five outings he is batting .300 with a triple, four walks and an RBI.
• Corbin Carroll has 22 doubles, 14 triples, 27 home runs and 44 walks. He's batting .251 and slugging .550 with an on-base percentage of .327.
• Among all qualifying players, he ranks 99th in batting average, 81st in on-base percentage and seventh in slugging percentage.
• Carroll has picked up a hit in six games in a row. During his last 10 games he is hitting .286 with two doubles, three home runs, six walks and six RBIs.
• Ketel Marte leads Arizona with 103 hits and an OBP of .395 this season.
• Lourdes Gurriel Jr. has been key for Arizona with 112 hits, an OBP of .296 plus a slugging percentage of .412.
• Gurriel has safely hit in five games in a row. During his last five outings he is batting .300 with a double, two home runs, a walk and seven RBIs.

Guardians Player Leaders

• Jose Ramirez has racked up a team-best OBP (.363) and slugging percentage (.513), while leading the Guardians in hits (133, while batting .290).
• Including all qualified hitters, he is 18th in batting average, while his on-base percentage ranks 23rd and he is 15th in slugging.
• Steven Kwan has 22 doubles, a triple, 10 home runs and 42 walks while hitting .280. He's slugging .395 with an on-base percentage of .339.
• Including all qualified hitters, he ranks 29th in batting average, 59th in on-base percentage and 118th in slugging percentage.
• Carlos Santana has nine doubles, 11 home runs and 52 walks while batting .227.
• Kyle Manzardo has 14 doubles, two triples, 21 home runs and 40 walks while hitting .236.

Diamondbacks vs Guardians Head to Head

• 8/18/2025: 3-1 CLE (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/7/2024: 5-3 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/7/2024: 7-3 ARI (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/5/2024: 7-6 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/18/2023: 12-3 CLE (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/17/2023: 6-3 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 6/16/2023: 5-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!