De'Von Achane Fantasy Football Week 10: Stats and Projections vs. Bills

Miami Dolphins running back De'Von Achane will match up with the 28th-ranked rushing defense of the Buffalo Bills (141.4 yards conceded per game) in Week 10, at 1 p.m. ET on Sunday.

Is Achane a DFS option for you this week, as he goes up against the Bills? More stats and information can be found below, so check it out.

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De'Von Achane Week 10 Fantasy Football Projection

• Matchup: Miami Dolphins vs. Buffalo Bills
• Game Date: November 9, 2025
• Game Time: 1 p.m.
• Projected Fantasy Points: 15.6
• PPR Projected Fantasy Points: 18.4
• Projected Rushing Yards: 73.32
• Projected Rushing TDs: 0.46
• Projected Receiving Yards: 38.41
• Projected Receiving TDs: 0.29

Projections provided by numberFire

Achane Fantasy Performance

• Achane has produced 130.0 fantasy points in 2025 (14.4 per game), which ranks him sixth at the RB position. Overall, he's the No. 22 player in fantasy football.
• During his last three games, Achane has 35.5 total fantasy points (11.8 per game), toting the ball 45 times for 216 yards and zero touchdowns. In the receiving game, he has added 79 yards on 14 catches (22 targets) with one TDs.
• Achane has generated 73.1 fantasy points (14.6 per game) in his last five games, as he's scampered for 360 yards with two touchdowns on 71 attempts. In the passing game, he has contributed 131 yards on 24 receptions (35 targets) with two TDs.
• The high point of Achane's fantasy season so far was Week 6 against the Los Angeles Chargers, when he caught four balls on six targets for 22 yards, good for 27.0 fantasy points.
• From a fantasy perspective, De'Von Achane delivered his lowest fantasy-point total of the season (9.1 points) in Week 3 against the Buffalo Bills, rushing for 62 yards on 12 carries with seven catches for 29 yards.

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Bills Defensive Performance

• No QBs have recorded more than 300 yards passing in a game versus Buffalo this season.
• The Bills have allowed at least one passing TD to five opposing QBs this year.
• Buffalo has allowed at least two passing TDs to two opposing QBs this year.
• The Bills have not allowed someone to throw for three or more touchdowns against them in a game this season.
• Buffalo has allowed three players to put up more than 100 yards receiving in a game this season.
• The Bills have allowed a TD catch by seven players this season.
• Buffalo has not allowed an opposing player to catch more than one touchdown pass in a game this year.
• Two players have put up more than 100 yards rushing in a game versus the Bills this season.
• Buffalo has allowed 10 players to score at least one rushing touchdown versus them this year.
• The Bills have given up at least two rushing TDs to two players this season.

Want more data and analysis on De'Von Achane? Check out FanDuel Research for all the latest and in-depth fantasy and betting coverage.