Cubs vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for July 22

Odds updated as of 3:12 p.m.

MLB action on Tuesday includes the Chicago Cubs taking on the Kansas City Royals.

We've got you covered, in terms of the vital info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Royals Game Info

• Chicago Cubs (59-41) vs. Kansas City Royals (49-52)
• Date: Tuesday, July 22, 2025
• Time: 8:05 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and FDSKC

Cubs vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-240) | KC: (+198)
• Spread: CHC: -1.5 (-111) | KC: +1.5 (-108)
• Total: 9 -- Over: (-102) | Under: (-120)

Cubs vs Royals Probable Starting Pitchers

Probable Pitchers: Matthew Boyd (Cubs) - 10-3, 2.34 ERA vs Richard Hill (Royals) - 0-0, 0.00 ERA

This contest's pitching matchup is set, as the Cubs will send Matthew Boyd (10-3) to the mound, while Richard Hill will answer the bell for the Royals. Boyd and his team are 8-10-0 ATS this season when he starts. When Boyd starts a game and his team is the favorite on the moneyline, they have a record of 9-3. Hill did not pitch as a moneyline underdog a season ago.

Cubs vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (65.7%)

Cubs vs Royals Moneyline

• Chicago is a -240 favorite on the moneyline, while Kansas City is a +198 underdog on the road.

Cubs vs Royals Spread

• The Cubs are 1.5-run home favorites on the runline against the Royals. The Cubs are -111 to cover, and the Royals are -108.

Cubs vs Royals Over/Under

• The over/under for Cubs-Royals on July 22 is 9. The over is -102, and the under is -120.

Bet on Chicago Cubs vs. Kansas City Royals on FanDuel today!

Cubs vs Royals Betting Trends

• The Cubs have been victorious in 44, or 69.8%, of the 63 contests they have been chosen as favorites in this season.
• Chicago has not lost in seven games when named as a moneyline favorite of -240 or better.
• The Cubs and their opponents have hit the over in 49 of their 97 games with a total set by oddsmakers this season.
• The Cubs have posted a record of 48-49-0 against the spread this season.
• The Royals have compiled a 29-32 record in games they were listed as the moneyline underdog (winning 47.5% of those games).
• Kansas City has played as a moneyline underdog of +198 or longer in just one game this season, which it lost.
• The Royals have had an over/under set by bookmakers 99 times, and have combined with opponents to go over the total in 39 of those games (39-58-2).
• The Royals have collected a 50-49-0 record against the spread this season (covering 50.5% of the time).

Cubs Player Leaders

• Kyle Tucker leads Chicago in OBP (.382) this season, fueled by 102 hits. He has a .276 batting average and a slugging percentage of .496.
• Among qualified hitters in MLB, his batting average ranks 44th, his on-base percentage ranks ninth, and he is 23rd in slugging.
• Pete Crow-Armstrong leads Chicago in slugging percentage (.556) and total hits (104) this season. He's batting .270 with an on-base percentage of .306.
• He is 55th in batting average, 124th in on-base percentage and eighth in slugging in the majors.
• Crow-Armstrong takes a four-game streak with at least one hit into this one. In his last five games he is batting .286 with three doubles, a home run and two RBIs.
• Seiya Suzuki has collected 99 base hits, an OBP of .314 and a slugging percentage of .539 this season.
• Nico Hoerner has an OPS of .708, fueled by an OBP of .332 and a team-best slugging percentage of .375 this season.

Royals Player Leaders

• Bobby Witt Jr. has put up a slugging percentage of .491 and has 115 hits, both team-best numbers for the Royals. He's batting .288 and with an on-base percentage of .339.
• Including all the qualified hitters in the majors, he ranks 20th in batting average, 62nd in on-base percentage and 26th in slugging percentage.
• Maikel Garcia leads his team with a .347 OBP. He has a batting average of .293 while slugging .446.
• Including all qualified hitters, he ranks 12th in batting average, 51st in on-base percentage and 63rd in slugging percentage.
• Vinnie Pasquantino has 14 doubles, a triple, 15 home runs and 29 walks while batting .264.
• Salvador Perez is hitting .253 with 26 doubles, 17 home runs and 18 walks.

Cubs vs Royals Head to Head

• 7/21/2025: 12-4 KC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/28/2024: 7-3 CHC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 7/27/2024: 9-4 CHC (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 7/26/2024: 6-0 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/20/2023: 4-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 8/19/2023: 6-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 8/18/2023: 4-3 KC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)

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