Cubs vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for July 22

Odds updated as of 7:11 p.m.

On Tuesday in MLB, the Chicago Cubs are playing the Kansas City Royals.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Cubs vs Royals Game Info

• Chicago Cubs (59-41) vs. Kansas City Royals (49-52)
• Date: Tuesday, July 22, 2025
• Time: 8:05 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and FDSKC

Cubs vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-255) | KC: (+210)
• Spread: CHC: -1.5 (-128) | KC: +1.5 (+106)
• Total: 9 -- Over: (-102) | Under: (-120)

Cubs vs Royals Probable Starting Pitchers

Probable Pitchers: Matthew Boyd (Cubs) - 10-3, 2.34 ERA vs Richard Hill (Royals) - 0-0, 0.00 ERA

The Cubs will give the nod to Matthew Boyd (10-3, 2.34 ERA), who is eyeing win No. 11 on the season, and the Royals will turn to Richard Hill. When Boyd starts, his team is 8-10-0 against the spread this season. Boyd's team has been victorious in 75% of the games he's started as the moneyline favorite with a record of 9-3. Hill and his team were moneyline underdogs each time he pitched a season ago.

Cubs vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (65.7%)

Cubs vs Royals Moneyline

• The Cubs vs Royals moneyline has Chicago as a -255 favorite, while Kansas City is a +210 underdog on the road.

Cubs vs Royals Spread

• The Cubs are hosting the Royals and are favored by 1.5 runs on the spread. The Cubs are -128 to cover the runline, with the Royals being +106.

Cubs vs Royals Over/Under

• An over/under of 9 has been set for Cubs-Royals on July 22, with the over being -102 and the under -120.

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Cubs vs Royals Betting Trends

• The Cubs have been favorites in 63 games this season and have come away with the win 44 times (69.8%) in those contests.
• Chicago has not lost in seven games when named as a moneyline favorite of -255 or better.
• Contests with the Cubs have gone over the total set by bookmakers in 49 of 97 chances this season.
• The Cubs are 48-49-0 against the spread in their 97 games that had a posted line this season.
• The Royals have gone 29-32 in games they were the underdog on the moneyline (winning 47.5% of those games).
• Kansas City has yet to play a game with moneyline odds of +210 or longer.
• In the 99 games bookmakers have set an over/under for the Royals, they have combined with opponents to go over the total 39 times (39-58-2).
• The Royals have covered 50.5% of their games this season, going 50-49-0 against the spread.

Cubs Player Leaders

• Kyle Tucker has 102 hits this season and a team-best OBP of .382. He has a .276 batting average and a slugging percentage of .496.
• He ranks 44th in batting average, ninth in on-base percentage, and 23rd in slugging among qualifying batters in MLB.
• Pete Crow-Armstrong has 104 hits to go with a slugging percentage of .556, both of which are tops among Chicago hitters this season. He's batting .270 with an on-base percentage of .306.
• Among all qualified, he is 55th in batting average, 124th in on-base percentage and eighth in slugging percentage.
• Crow-Armstrong enters this game looking to extend his four-game hit streak. In his last five games he is hitting .286 with three doubles, a home run and two RBIs.
• Seiya Suzuki has 99 hits this season and has a slash line of .258/.314/.539.
• Nico Hoerner leads Chicago in slugging percentage (.375) thanks to 24 extra-base hits.

Royals Player Leaders

• Bobby Witt Jr. has accumulated a team-high slugging percentage (.491) while pacing the Royals in hits (115). He's batting .288 and with an on-base percentage of .339.
• Including all qualified players, he ranks 20th in batting average, while his on-base percentage is 62nd and he is 26th in slugging.
• Maikel Garcia leads his team with a .347 on-base percentage. He has a batting average of .293 while slugging .446.
• Including all qualifying hitters, his batting average puts him 12th, his on-base percentage is 51st, and he is 63rd in slugging.
• Vinnie Pasquantino has 14 doubles, a triple, 15 home runs and 29 walks while batting .264.
• Salvador Perez has 26 doubles, 17 home runs and 18 walks while hitting .253.

Cubs vs Royals Head to Head

• 7/21/2025: 12-4 KC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/28/2024: 7-3 CHC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 7/27/2024: 9-4 CHC (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 7/26/2024: 6-0 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/20/2023: 4-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 8/19/2023: 6-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 8/18/2023: 4-3 KC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)

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