Cubs vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 6

Odds updated as of 2:11 p.m.

The Wednesday slate in MLB includes a matchup between the Chicago Cubs and the Cincinnati Reds.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information about this matchup.

Cubs vs Reds Game Info

• Chicago Cubs (65-48) vs. Cincinnati Reds (60-54)
• Date: Wednesday, August 6, 2025
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and FDSOH

Cubs vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-184) | CIN: (+154)
• Spread: CHC: -1.5 (+120) | CIN: +1.5 (-144)
• Total: 7.5 -- Over: (-100) | Under: (-122)

Cubs vs Reds Probable Starting Pitchers

Probable Pitchers: Cade Horton (Cubs) - 5-3, 3.42 ERA vs Andrew Abbott (Reds) - 8-1, 2.15 ERA

The probable pitchers are Cade Horton (5-3) for the Cubs and Andrew Abbott (8-1) for the Reds. Horton's team is 5-8-0 against the spread this season in his starts. When Horton starts a game and his team is the favorite on the moneyline, they have a record of 8-1. The Reds are 12-6-0 against the spread when Abbott starts. The Reds have been the underdog on the moneyline in seven of Abbott's starts this season, and they went 5-2 in those games.

Cubs vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (58.6%)

Cubs vs Reds Moneyline

• Chicago is a -184 favorite on the moneyline, while Cincinnati is a +154 underdog on the road.

Cubs vs Reds Spread

• The Cubs are favored by 1.5 runs at home versus the Reds. The Cubs are +120 to cover the spread, while the Reds are -144.

Cubs vs Reds Over/Under

• A total of 7.5 runs has been set for the Cubs-Reds game on Aug. 6, with the over available at -100 and the under at -122.

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Cubs vs Reds Betting Trends

• The Cubs have won in 49, or 66.2%, of the 74 contests they have been named as odds-on favorites in this year.
• Chicago has a record of 14-4 in contests when sportsbooks favor them by -184 or more on the moneyline.
• The Cubs and their opponents have gone over in 55 of their 110 games with a total set by sportsbooks this season.
• In 110 games with a line this season, the Cubs have a mark of 52-58-0 against the spread.
• The Reds have been the moneyline underdog 59 total times this season. They've gone 31-28 in those games.
• Cincinnati has a 1-6 record (winning only 14.3% of its games) when it has played as a moneyline underdog of +154 or longer.
• The Reds have played in 107 games with a set over/under, and have combined with opponents to go over the total 43 times (43-60-4).
• The Reds have gone 58-49-0 ATS this season.

Cubs Player Leaders

• Kyle Tucker leads Chicago in OBP (.384) this season, fueled by 111 hits. He has a .271 batting average and a slugging percentage of .474.
• Among qualifying hitters in the majors, his batting average ranks 52nd, his on-base percentage ranks sixth, and he is 33rd in slugging.
• Pete Crow-Armstrong has 115 hits, which leads Chicago batters this season. He's batting .266 with 62 extra-base hits. He's also slugging .544 with an on-base percentage of .304.
• Among qualified hitters, his batting average ranks him 65th, his on-base percentage 126th, and his slugging percentage ninth.
• Seiya Suzuki has collected 105 base hits, an OBP of .314 and a slugging percentage of .504 this season.
• Nico Hoerner leads Chicago in slugging percentage (.379) thanks to 26 extra-base hits.

Reds Player Leaders

• Elly De La Cruz has accumulated a team-high slugging percentage (.478) and leads the Reds in hits (122). He's batting .279 and with an on-base percentage of .356.
• Including all qualified hitters in MLB, he ranks 32nd in batting average, 32nd in on-base percentage and 30th in slugging percentage.
• TJ Friedl has a .374 on-base percentage to lead his team. He has a batting average of .273 while slugging .398.
• He is currently 47th in batting average, 14th in on-base percentage and 106th in slugging percentage among all qualified hitters.
• Spencer Steer is hitting .239 with 15 doubles, two triples, 13 home runs and 32 walks.
• Matt McLain is batting .223 with 12 doubles, 11 home runs and 41 walks.

Cubs vs Reds Head to Head

• 8/5/2025: 5-1 CIN (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 8/4/2025: 3-2 CIN (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/1/2025: 7-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 5/31/2025: 2-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 5/30/2025: 6-2 CIN (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/25/2025: 11-8 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/24/2025: 6-4 CIN (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/23/2025: 13-6 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/29/2024: 3-0 CIN (Favorite: Reds, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/28/2024: 3-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -130, Underdog Moneyline: +110)

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