Cubs vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 5

Odds updated as of 2:11 a.m.

Tuesday's slate in the MLB includes a matchup between the Chicago Cubs and the Cincinnati Reds.

We've got you covered, in terms of the vital info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Reds Game Info

• Chicago Cubs (65-47) vs. Cincinnati Reds (59-54)
• Date: Tuesday, August 5, 2025
• Time: 8:05 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: TBS, MARQ, and FDSOH

Cubs vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-178) | CIN: (+150)
• Spread: CHC: -1.5 (+122) | CIN: +1.5 (-146)
• Total: 8 -- Over: (-105) | Under: (-115)

Cubs vs Reds Probable Starting Pitchers

Probable Pitchers: Shota Imanaga (Cubs) - 8-4, 3.25 ERA vs Zack Littell (Reds) - 8-8, 3.58 ERA

The Cubs will give the nod to Shota Imanaga (8-4, 3.25 ERA), who is eyeing win No. 9 on the season, and the Reds will counter with Zack Littell (8-8, 3.58 ERA). Imanaga and his team have a record of 8-7-0 against the spread when he starts. When Imanaga starts a game and his team is the favorite on the moneyline, they have a record of 6-3. The Reds have gone 9-13-0 ATS in Littell's 22 starts that had a set spread. The Reds are 6-6 in Littell's 12 starts this season that they were the moneyline underdog.

Cubs vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (58.7%)

Cubs vs Reds Moneyline

• The Cubs vs Reds moneyline has Chicago as a -178 favorite, while Cincinnati is a +150 underdog on the road.

Cubs vs Reds Spread

• The Cubs are 1.5-run home favorites on the runline against the Reds. The Cubs are +122 to cover, and the Reds are -146.

Cubs vs Reds Over/Under

• The over/under for the Cubs versus Reds game on Aug. 5 has been set at 8, with -105 odds on the over and -115 odds on the under.

Bet on Chicago Cubs vs. Cincinnati Reds on FanDuel today!

Cubs vs Reds Betting Trends

• The Cubs have won in 49, or 67.1%, of the 73 contests they have been named as odds-on favorites in this year.
• Chicago has a record of 15-3 when favored by -178 or more this year.
• The Cubs and their opponents have hit the over in 55 of their 109 games with a total set by oddsmakers this season.
• The Cubs are 52-57-0 against the spread in their 109 games with a line set by sportsbooks this season.
• The Reds have been the underdog on the moneyline 58 total times this season. They've finished 30-28 in those games.
• When playing as a moneyline underdog with odds of +150 or longer, Cincinnati has gone 3-7 (30%).
• The Reds have played in 106 games with a set over/under, and have combined with their opponents to go over the total 43 times (43-59-4).
• The Reds have put together a 57-49-0 record against the spread this season (covering 53.8% of the time).

Cubs Player Leaders

• Kyle Tucker leads Chicago with an OBP of .388 this season while batting .274 with 75 walks and 75 runs scored. He has a slugging percentage of .479.
• Among the qualified hitters in MLB, his batting average ranks 44th, his on-base percentage ranks sixth, and he is 31st in slugging.
• Pete Crow-Armstrong leads Chicago in total hits (114) this season while batting .266 with 62 extra-base hits. He's slugging .547 with an on-base percentage of .304.
• Among qualifying hitters, his batting average places him 65th, his on-base percentage 125th, and his slugging percentage ninth.
• Seiya Suzuki is batting .247 with a .504 slugging percentage and 82 RBI this year.
• Nico Hoerner leads Chicago with a slugging percentage of .382, fueled by 26 extra-base hits.

Reds Player Leaders

• Elly De La Cruz has put up a team-best slugging percentage (.483) while pacing the Reds in hits (122). He's batting .282 and with an on-base percentage of .359.
• Including all the qualifying players in the majors, he is 25th in batting average, 30th in on-base percentage and 29th in slugging percentage.
• TJ Friedl has a .373 OBP to lead his team. He has a batting average of .271 while slugging .397.
• Including all qualified hitters, he ranks 50th in batting average, 17th in on-base percentage and 109th in slugging percentage.
• Spencer Steer has 15 doubles, two triples, 12 home runs and 32 walks while hitting .236.
• Matt McLain is hitting .225 with 12 doubles, 11 home runs and 41 walks.

Cubs vs Reds Head to Head

• 8/4/2025: 3-2 CIN (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/1/2025: 7-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 5/31/2025: 2-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 5/30/2025: 6-2 CIN (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/25/2025: 11-8 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/24/2025: 6-4 CIN (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/23/2025: 13-6 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/29/2024: 3-0 CIN (Favorite: Reds, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/28/2024: 3-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/27/2024: 1-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -126, Underdog Moneyline: +108)

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