Cubs vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for May 4

Odds updated as of 6:13 p.m.

On Monday in MLB, the Chicago Cubs are playing the Cincinnati Reds.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information about this matchup.

Cubs vs Reds Game Info

• Chicago Cubs (22-12) vs. Cincinnati Reds (20-14)
• Date: Monday, May 4, 2026
• Time: 7:10 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and Reds.TV

Cubs vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-215) | CIN: (+180)
• Spread: CHC: -1.5 (-115) | CIN: +1.5 (-104)
• Total: 11.5 -- Over: (-110) | Under: (-110)

Cubs vs Reds Probable Starting Pitchers

Probable Pitchers: Edward Cabrera (Cubs) - 3-0, 3.06 ERA vs Chase Petty (Reds) - 0-0, 0.00 ERA

This contest's pitching matchup is set, as the Cubs will send Edward Cabrera (3-0) to the mound, while Chase Petty will get the nod for the Reds. Cabrera's team is 4-2-0 against the spread in his starts this season. Cabrera's team is 4-1 this season when he starts and they are the moneyline favorite. Last season Petty's team did not cover in either of his two games pitched with a spread. Petty's team was the moneyline underdog just once in a game he pitched a season ago, and lost.

Cubs vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (67.4%)

Cubs vs Reds Moneyline

• Looking at the moneyline for Cubs-Reds, Chicago is the favorite at -215, and Cincinnati is +180 playing on the road.

Cubs vs Reds Spread

• The Cubs are favored by 1.5 runs at home against the Reds. The Cubs are -115 to cover the spread, while the Reds are -104.

Cubs vs Reds Over/Under

• The over/under for the Cubs versus Reds game on May 4 has been set at 11.5, with -110 odds on the over and -110 odds on the under.

Bet on Chicago Cubs vs. Cincinnati Reds on FanDuel today!

Cubs vs Reds Betting Trends

• The Cubs have won in 15, or 68.2%, of the 22 contests they have been named as odds-on favorites in this year.
• Chicago has been listed as a favorite of -215 or more on two occasions this season and split those games.
• Contests with the Cubs have gone over the total set by sportsbooks in 22 of 34 chances this season.
• The Cubs are 17-17-0 against the spread in their 34 games that had a posted line this season.
• The Reds have compiled a 14-8 record in games they were listed as the moneyline underdog (winning 63.6% of those games).
• Cincinnati has yet to play as a moneyline underdog of +180 or longer.
• The Reds have played in 33 games with an over/under set, and have combined with their opponents to go over the total 20 times (20-12-1).
• The Reds have a 20-13-0 record against the spread this season (covering 60.6% of the time).

Cubs Player Leaders

• Nico Hoerner leads Chicago with a slugging percentage of .466, fueled by 14 extra-base hits. He has a .301 batting average and an on-base percentage of .375.
• Among all qualified batters in MLB, he is 26th in batting average, 38th in on-base percentage, and 48th in slugging.
• Hoerner hopes to build on a four-game hitting streak in this matchup. During his last five outings he is hitting .263 with three doubles, a walk and three RBIs.
• Dansby Swanson has two doubles, a triple, six home runs and 21 walks. He's batting .213 and slugging .417 with an on-base percentage of .338.
• His batting average ranks 146th among qualified players, his on-base percentage 78th, and his slugging percentage 78th.
• Ian Happ leads his team in OBP (.381) and total hits (30) this season.
• Happ enters this game with two games in a row with at least one hit. In his last five games he is hitting .333 with two doubles, a triple, a home run, seven walks and an RBI.
• Moises Ballesteros is batting .317 with a .380 OBP and 18 RBI for Chicago this season.

Reds Player Leaders

• Sal Stewart has six doubles, nine home runs and 18 walks while hitting .252. He's slugging .512 with an on-base percentage of .340.
• Including all the qualified hitters in MLB, he ranks 81st in batting average, 74th in on-base percentage and 26th in slugging percentage.
• Elly De La Cruz's 36 hits, .349 on-base percentage and .541 slugging percentage are all team-highs. He has a batting average of .271.
• He ranks 50th in batting average, 67th in on-base percentage and 17th in slugging percentage in the big leagues.
• Nathaniel Lowe is hitting .274 with five doubles, five home runs and seven walks.
• Spencer Steer is batting .245 with six doubles, five home runs and 10 walks.

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