Cubs vs Phillies Prediction, Odds, Moneyline, Spread & Over/Under for April 25

Odds updated as of 1:13 p.m.

The Chicago Cubs versus the Philadelphia Phillies is on the MLB schedule for Friday.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Cubs vs Phillies Game Info

• Chicago Cubs (16-10) vs. Philadelphia Phillies (13-12)
• Date: Friday, April 25, 2025
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MLB Network, MARQ, and NBCS-PH

Cubs vs Phillies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-158) | PHI: (+134)
• Spread: CHC: -1.5 (+130) | PHI: +1.5 (-156)
• Total: 8 -- Over: (-118) | Under: (-104)

Cubs vs Phillies Probable Starting Pitchers

Probable Pitchers: Colin Rea (Cubs) - 0-0, 1.32 ERA vs Taijuan Walker (Phillies) - 1-1, 2.29 ERA

The probable pitchers are Colin Rea for the Cubs and Taijuan Walker (1-1) for the Phillies. Rea has a record of 2-0-0 ATS in two starts with a spread this season. Rea has yet to start a game this season when his team was the moneyline favorite. The Phillies have a 2-2-0 record against the spread in Walker's starts. The Phillies were the moneyline underdog for one Walker start this season -- they won.

Cubs vs Phillies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (57.1%)

Cubs vs Phillies Moneyline

• Chicago is the favorite, -158 on the moneyline, while Philadelphia is a +134 underdog on the road.

Cubs vs Phillies Spread

• The Phillies are +1.5 on the spread (-156 to cover), and Chicago is +130 to cover the runline.

Cubs vs Phillies Over/Under

• A combined run total of 8 has been set for Cubs-Phillies on April 25, with the over at -118 and the under at -104.

Bet on Chicago Cubs vs. Philadelphia Phillies on FanDuel today!

Cubs vs Phillies Betting Trends

• The Cubs have been victorious in nine, or 81.8%, of the 11 contests they have been chosen as favorites in this season.
• This year Chicago has won two of three games when listed as at least -158 on the moneyline.
• The Cubs' games have gone over the total in 17 of their 25 opportunities.
• The Cubs have an against the spread record of 14-11-0 in 25 games with a line this season.
• The Phillies have won 50% of the games this season they were the moneyline underdog (3-3).
• Philadelphia has not played a game this season with moneyline odds of +134 or longer.
• In the 25 games oddsmakers have set an over/under for the Phillies, they have combined with opponents to go over the total 12 times (12-13-0).
• The Phillies have covered 52% of their games this season, going 13-12-0 against the spread.

Cubs Player Leaders

• Kyle Tucker leads Chicago with 32 hits and an OBP of .423, plus a team-best slugging percentage of .637. He's batting .314.
• Among all qualified hitters, he ranks 18th in batting average, his on-base percentage ranks seventh, and he is fifth in slugging.
• Pete Crow-Armstrong is hitting .294 with nine doubles, a triple, five home runs and six walks. He's slugging .549 with an on-base percentage of .339.
• He ranks 34th in batting average, 65th in on-base percentage and 18th in slugging in the majors.
• Crow-Armstrong has picked up at least one hit in two games in a row. During his last five outings he is hitting .429 with three doubles, two home runs, a walk and seven RBI.
• Carson Kelly has 13 hits this season and has a slash line of .342/.519/.895.
• Ian Happ has been key for Chicago with 30 hits, an OBP of .352 plus a slugging percentage of .366.
• Happ has hit safely in three straight games. During his last five outings he is batting .409 with a double, a home run, three walks and five RBI.

Phillies Player Leaders

• Kyle Schwarber has racked up 23 hits with a .411 on-base percentage, leading the Phillies in both categories. He's batting .258 and slugging .528.
• He ranks 72nd in batting average, 13th in on-base percentage and 27th in slugging percentage among all qualified hitters in the big leagues.
• Bryce Harper is hitting .250 with four doubles, five home runs and 21 walks. He's slugging .457 with an on-base percentage of .389.
• Including all qualified hitters, his batting average places him 78th, his on-base percentage ranks 27th, and he is 53rd in slugging.
• Bryson Stott has a .440 slugging percentage, which leads the Phillies.
• Nicholas Alexander Castellanos is slugging .440 to pace his team.

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