Cubs vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 27

Odds updated as of 9:11 a.m.

The MLB's Wednesday slate includes the Chicago Cubs taking on the San Francisco Giants.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Giants Game Info

• Chicago Cubs (76-56) vs. San Francisco Giants (64-68)
• Date: Wednesday, August 27, 2025
• Time: 9:45 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and MARQ

Cubs vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-126) | SF: (+108)
• Spread: CHC: -1.5 (+136) | SF: +1.5 (-164)
• Total: 8.5 -- Over: (-108) | Under: (-112)

Cubs vs Giants Probable Starting Pitchers

Probable Pitchers: Colin Rea (Cubs) - 10-5, 3.96 ERA vs Carson Whisenhunt (Giants) - 1-1, 4.91 ERA

The probable pitchers are Colin Rea (10-5) for the Cubs and Carson Whisenhunt (1-1) for the Giants. Rea and his team have a record of 13-8-0 against the spread when he starts. Rea's team has a record of 8-5 this season when he starts and they are the favorite on the moneyline. The Giants have gone 2-2-0 ATS in Whisenhunt's four starts that had a set spread. The Giants were named the moneyline underdog for two Whisenhunt starts this season -- they split the games.

Cubs vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (58.9%)

Cubs vs Giants Moneyline

• Looking at the moneyline for Giants-Cubs, San Francisco is the underdog at +108, and Chicago is -126 playing on the road.

Cubs vs Giants Spread

• The Cubs are 1.5-run road favorites on the runline against the Giants. The Cubs are +136 to cover, and the Giants are -164.

Cubs vs Giants Over/Under

• The over/under for the Cubs versus Giants contest on Aug. 27 has been set at 8.5, with -108 odds on the over and -112 odds on the under.

Bet on Chicago Cubs vs. San Francisco Giants on FanDuel today!

Cubs vs Giants Betting Trends

• The Cubs have been chosen as favorites in 88 games this year and have walked away with the win 57 times (64.8%) in those games.
• Chicago has a record of 49-23 when favored by -126 or more this year.
• The Cubs and their opponents have gone over the total this season in 59 of their 128 opportunities.
• The Cubs have posted a record of 60-68-0 against the spread this season.
• The Giants have won 24 of the 52 games they were the underdog on the moneyline this season (46.2%).
• When playing as a moneyline underdog with odds of +108 or longer, San Francisco has a 17-20 record (winning 45.9% of its games).
• The Giants have played in 131 games with an over/under set, and have combined with their opponents to go over the total 60 times (60-65-6).
• The Giants have covered 43.5% of their games this season, going 57-74-0 against the spread.

Cubs Player Leaders

• Kyle Tucker leads Chicago in OBP (.374) this season, fueled by 122 hits. He has a .262 batting average and a slugging percentage of .462.
• Among all qualified hitters in baseball, he ranks 68th in batting average, 10th in on-base percentage, and 52nd in slugging.
• Tucker has picked up at least one hit in four straight games. In his last five games he is batting .300 with a double, three home runs, three walks and seven RBIs.
• Pete Crow-Armstrong leads Chicago with 127 hits. He is batting .256 this season and has 66 extra-base hits. He's also slugging .510 with an on-base percentage of .295.
• Among qualifiers, he is 87th in batting average, 142nd in on-base percentage and 15th in slugging percentage.
• Nico Hoerner leads Chicago in slugging percentage (.370) powered by 28 extra-base hits.
• Seiya Suzuki is batting .244 with a .319 OBP and 87 RBI for Chicago this season.
• Suzuki brings a three-game hitting streak into this game. In his last five games he is batting .167 with four walks and an RBI.

Giants Player Leaders

• Rafael Devers has racked up 124 hits with a .372 on-base percentage, leading the Giants in both statistics. He's batting .252 and slugging .460.
• Including all the qualified hitters in the big leagues, his batting average puts him 93rd, his on-base percentage ranks 13th, and he is 53rd in slugging.
• Jung Hoo Lee is batting .259 with 29 doubles, 10 triples, seven home runs and 41 walks. He's slugging .408 with an on-base percentage of .322.
• He ranks 77th in batting average, 92nd in on-base percentage and 98th in slugging percentage in the majors.
• Willy Adames is hitting .223 with 18 doubles, two triples, 22 home runs and 63 walks.
• Heliot Ramos leads his team with a .404 slugging percentage.

Cubs vs Giants Head to Head

• 8/26/2025: 5-2 SF (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 5/7/2025: 3-1 SF (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 5/6/2025: 14-5 SF (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 5/5/2025: 9-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/27/2024: 5-3 CHC (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/26/2024: 4-3 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/25/2024: 5-1 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 6/24/2024: 5-4 SF (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/19/2024: 6-5 CHC (Favorite: Cubs, Spread: -1.5, Total: 11, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 6/18/2024: 5-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

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