Cubs vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 27

Odds updated as of 9:11 p.m.

On Wednesday in MLB, the Chicago Cubs are playing the San Francisco Giants.

We've got you covered, in terms of the vital information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Giants Game Info

• Chicago Cubs (76-56) vs. San Francisco Giants (64-68)
• Date: Wednesday, August 27, 2025
• Time: 9:45 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and MARQ

Cubs vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-126) | SF: (+108)
• Spread: CHC: -1.5 (+128) | SF: +1.5 (-154)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Cubs vs Giants Probable Starting Pitchers

Probable Pitchers: Colin Rea (Cubs) - 10-5, 3.96 ERA vs Carson Whisenhunt (Giants) - 1-1, 4.91 ERA

The probable starters are Colin Rea (10-5) for the Cubs and Carson Whisenhunt (1-1) for the Giants. Rea's team is 13-8-0 against the spread this season in his starts. When Rea starts a game and his team is the favorite on the moneyline, they have a record of 8-5. The Giants have gone 2-2-0 ATS in Whisenhunt's four starts with a set spread. The Giants were the underdog on the moneyline for two Whisenhunt starts this season -- they split the games.

Cubs vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (58.9%)

Cubs vs Giants Moneyline

• Chicago is the favorite, -126 on the moneyline, while San Francisco is a +108 underdog despite being at home.

Cubs vs Giants Spread

• The Giants are hosting the Cubs, and are +1.5 on the runline. The Giants are +128 to cover the spread, and the Cubs are -154.

Cubs vs Giants Over/Under

• The over/under for the Cubs versus Giants contest on Aug. 27 has been set at 8.5, with -110 odds on the over and -110 odds on the under.

Bet on Chicago Cubs vs. San Francisco Giants on FanDuel today!

Cubs vs Giants Betting Trends

• The Cubs have been victorious in 57, or 64.8%, of the 88 contests they have been chosen as favorites in this season.
• Chicago has a record of 49-23 in contests when bookmakers favor them by -126 or more on the moneyline.
• Contests with the Cubs have gone over the total set by bookmakers in 59 of 128 chances this season.
• In 128 games with a line this season, the Cubs have a mark of 60-68-0 against the spread.
• The Giants have won 46.2% of the games this season they were the moneyline underdog (24-28).
• San Francisco has a record of 17-20 in games it has played as a moneyline underdog with odds of +108 or longer (45.9%).
• The Giants have had an over/under set by bookmakers 131 times, and have combined with opponents to go over the total in 60 of those games (60-65-6).
• The Giants have covered 43.5% of their games this season, going 57-74-0 ATS.

Cubs Player Leaders

• Kyle Tucker leads Chicago in OBP (.374) this season, fueled by 122 hits. He has a .262 batting average and a slugging percentage of .462.
• Among qualifying hitters in baseball, his batting average ranks 66th, his on-base percentage ranks ninth, and he is 50th in slugging.
• Tucker has recorded at least one hit in four straight games. During his last five outings he is batting .300 with a double, three home runs, three walks and seven RBIs.
• Pete Crow-Armstrong leads Chicago in total hits (127) this season while batting .256 with 66 extra-base hits. He's slugging .510 with an on-base percentage of .295.
• His batting average ranks 86th among qualified players, his on-base percentage 141st, and his slugging percentage 15th.
• Nico Hoerner has hit four homers with a team-high .370 SLG this season.
• Seiya Suzuki is batting .244 with a .319 OBP and 87 RBI for Chicago this season.
• Suzuki takes a three-game hitting streak into this matchup. During his last five outings he is batting .167 with four walks and an RBI.

Giants Player Leaders

• Rafael Devers has a team-high OBP (.372), and paces the Giants in hits (124). He's batting .252 and slugging.
• Including all qualified hitters, he is 92nd in batting average, while his on-base percentage is 12th and he is 51st in slugging.
• Jung Hoo Lee is hitting .259 with 29 doubles, 10 triples, seven home runs and 41 walks. He's slugging .408 with an on-base percentage of .322.
• Including all qualified hitters, he ranks 77th in batting average, 92nd in on-base percentage and 96th in slugging percentage.
• Willy Adames is hitting .223 with 18 doubles, two triples, 22 home runs and 63 walks.
• Heliot Ramos is slugging .404 to pace his team.

Cubs vs Giants Head to Head

• 8/26/2025: 5-2 SF (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 5/7/2025: 3-1 SF (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 5/6/2025: 14-5 SF (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 5/5/2025: 9-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/27/2024: 5-3 CHC (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/26/2024: 4-3 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/25/2024: 5-1 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 6/24/2024: 5-4 SF (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/19/2024: 6-5 CHC (Favorite: Cubs, Spread: -1.5, Total: 11, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 6/18/2024: 5-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

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