Cubs vs Diamondbacks Prediction, Odds, Moneyline, Spread & Over/Under for May 1

Odds updated as of 10:11 p.m.

MLB action on Friday includes the Chicago Cubs facing the Arizona Diamondbacks.

We've got you covered, in terms of the vital info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Diamondbacks Game Info

• Chicago Cubs (19-12) vs. Arizona Diamondbacks (16-14)
• Date: Friday, May 1, 2026
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and Dbacks.TV

Cubs vs Diamondbacks Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-134) | ARI: (+116)
• Spread: CHC: -1.5 (+158) | ARI: +1.5 (-192)
• Total: 7.5 -- Over: (+102) | Under: (-124)

Cubs vs Diamondbacks Probable Starting Pitchers

Probable Pitchers: Colin Rea (Cubs) - 3-1, 4.61 ERA vs Zac Gallen (Diamondbacks) - 1-1, 3.14 ERA

The Cubs will call on Colin Rea (3-1) against the Diamondbacks and Zac Gallen (1-1). Rea and his team are 2-1-0 ATS this season when he starts. Rea's team won his only start as a favorite this season. The Diamondbacks are 4-2-0 against the spread when Gallen starts. The Diamondbacks have a 2-2 record in Gallen's four starts this season when they were the underdog on the moneyline.

Cubs vs Diamondbacks Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (63.9%)

Cubs vs Diamondbacks Moneyline

• Looking at the moneyline for Diamondbacks-Cubs, Arizona is the underdog at +116, and Chicago is -134 playing at home.

Cubs vs Diamondbacks Spread

• The Diamondbacks are at the Cubs, and are +1.5 on the runline. The Diamondbacks are +158 to cover the spread, and the Cubs are -192.

Cubs vs Diamondbacks Over/Under

• An over/under of 7.5 has been set for Cubs-Diamondbacks on May 1, with the over being +102 and the under -124.

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Cubs vs Diamondbacks Betting Trends

• The Cubs have been favorites in 19 games this season and have come away with the win 12 times (63.2%) in those contests.
• This season Chicago has come away with a win seven times in 12 chances when named as a favorite of at least -134 on the moneyline.
• The Cubs and their opponents have gone over in 20 of their 31 games with a total set by sportsbooks this season.
• The Cubs are 15-16-0 against the spread in their 31 games that had a posted line this season.
• The Diamondbacks have won nine of the 20 games they were the moneyline underdog this season (45%).
• Arizona has gone 6-4 when playing as a moneyline underdog with odds of +116 or longer (60%).
• The Diamondbacks have combined with opponents to go over the total 18 times this season for an 18-11-1 record against the over/under.
• The Diamondbacks have a 20-10-0 record against the spread this season (covering 66.7% of the time).

Cubs Player Leaders

• Nico Hoerner leads Chicago OPS (.819) this season. He has a .291 batting average, an on-base percentage of .370, and a slugging percentage of .449.
• Among qualifying hitters in baseball, he is 30th in batting average, 35th in on-base percentage, and 58th in slugging.
• Hoerner will look for his third straight game with a hit in this contest. In his last five games he is hitting .250 with a double, two walks and three RBIs.
• Dansby Swanson has two doubles, a triple, six home runs and 20 walks. He's batting .214 and slugging .439 with an on-base percentage of .344.
• Among qualifying hitters, he is 141st in batting average, 68th in on-base percentage and 66th in slugging percentage.
• Swanson has picked up at least one hit in two games in a row. During his last five outings he is hitting .333 with a double, a triple, a home run, a walk and six RBIs.
• Ian Happ has 26 hits and is batting .230 this season.
• Moises Ballesteros has been key for Chicago with 24 hits, an OBP of .392 plus a slugging percentage of .620.

Diamondbacks Player Leaders

• Ildemaro Vargas has a team-high OBP (.398) and slugging percentage (.689), and leads the Diamondbacks in hits (34, while batting .378).
• Including all qualified hitters in the big leagues, his batting average places him first, his on-base percentage is 15th, and he is third in slugging.
• Vargas takes a 23-game hitting streak into this matchup. In his last 10 games he is batting .375 with a double, a triple, four home runs, a walk and 12 RBIs.
• Corbin Carroll is batting .296 with seven doubles, four triples, four home runs and 16 walks. He's slugging .571 with an on-base percentage of .397.
• He is 24th in batting average, 17th in on-base percentage and ninth in slugging percentage in the majors.
• Nolan Arenado is batting .276 with two doubles, five home runs and six walks.
• Geraldo Perdomo is hitting .236 with three doubles, three triples, a home run and 18 walks.

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